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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

A new study by Washington State University researchers suggests that a protein called CDK2 plays a critical role in heart damage caused by doxorubicin, a commonly used chemotherapy drug.

8 Nov 2018

New open source decision support tool could help clinicians chose chemotherapy drugs

The selection of a first-line chemotherapy drug to treat many types of cancer is often a clear-cut decision governed by standard-of-care protocols, but what drug should be used next if the first one fails?

8 Nov 2018

Study elucidates genetic causes of severe cardiomyopathies in children

Cardiac muscle degeneration (cardiomyopathy) is the most common cause of severe cardiac dysfunction and life-threatening cardiac arrhythmias in children. These severe disorders often lead to consideration of heart transplant. However, their actual cause - the genetic basis - has been poorly characterized.

7 Nov 2018

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Melbourne scientists have discovered how tumor development is driven by mutations in the most important gene in preventing cancer, p53.

7 Nov 2018

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong, in collaboration with scientists from Tsinghua University in China, The Rockefeller University, and The University of Texas MD Anderson Cancer Center in the United States, developed the first chemical inhibitors against a novel therapeutic target for treatment of acute myeloid leukemia, a fast-growing cancer of bone marrow and blood cells.

7 Nov 2018

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Scientists are making strides in developing liquid biopsies for brain tumors by detecting tumor DNA in the fluid from around the brain and spine.

7 Nov 2018

Experts study antibiotic resistance in recycled water

Bacteria that become resistant to antibiotics lead to an estimated 23,000 deaths and 2 million illnesses per year in the U.S. The Centers for Disease Control is launching an expansive effort to study various facets of the growing threat by funding researchers across the nation, including two prominent water experts at Virginia Tech.

7 Nov 2018

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

The U.S. Department of Defense has granted the "Impact Award" to explore new therapeutic options against advanced prostate cancer - scientifically known as castration-resistant or hormone therapy resistant prostate cancer- to a multidisciplinary team of researchers made up of the Prostate Cancer Clinical Research Unit of the Spanish National Cancer Research Center, led by David Olmos, the Prostate Cancer Translational Research Group of the Vall d'Hebron Institute of Oncology, led by Joaquín Mateo, and the Genetics and Solid Tumors Laboratory of the University of Washington, led by Colin Pritchard.

7 Nov 2018

Scientists discover new details about UHRF1 protein

Epigenetic changes often play an important role in cancer, because they cause the genetic material to be read incorrectly at certain locations. Genes that are especially critical are those that control the growth and death of cells.

7 Nov 2018

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

The human gut is teeming with billions of beneficial bacteria. Therapies that use antibiotics often destroy most of them.

7 Nov 2018

Researchers identify pathway to resolve allergic asthma

A group of Brazilian researchers succeeded in preventing allergic asthma from progressing in experimental models by increasing the amount of a protein. This increase, in turn, blocked the CD4+ T lymphocytes responsible for producing a cytokine that triggers a cascade of events resulting in the onset and progression of the disease.

6 Nov 2018

Cancer risk linked to mobile phone radiation in rats but cannot be extrapolated to humans

A new study on laboratory rats has shown that mobile phone radiation exposure is linked to cancers of the brain, heart and the adrenal glands. The rats however were exposed to very high amounts of radiation which is much more than what humans are exposed when they use cell phones.

5 Nov 2018

New research explains how large virus shells are formed

A virus, the simplest physical object in biology, consists of a protein shell called the capsid, which protects its nucleic acid genome -- RNA or DNA. The capsid can be cylindrical or conical in shape, but more commonly it assumes an icosahedral structure, like a soccer ball.

5 Nov 2018

Slime in showerheads could harbour dangerous lung bacteria finds study

A study has shown that the showerheads contain slime that can be home to potentially dangerous bacteria which lead to severe lung disease. Mycobacterial bacteria are responsible for lung diseases explain experts.

4 Nov 2018

Study offers new hope to patients with rare brain cancer

sGBM is a rare type of brain cancer in adults. The incidence varies from 2 to 5 per million people per year. For example, if Hong Kong's base population of 7.5 million people is taken as a reference, over 15 people will be diagnosed with sGBM tumors annually.

2 Nov 2018

Genetic factors linked to obesity may lower metabolic risk

Experts believe that where on the body people store surplus fat, whether round their middle or round the liver, may be genetically determined.

2 Nov 2018

New way of identifying potential cancer drugs could streamline development of therapies

A new way of identifying potential cancer drugs could streamline the development of therapies, following a discovery by scientists.

2 Nov 2018

Male rats exposed to high levels of radio frequency radiation develop cancer, finds study

The National Toxicology Program concluded there is clear evidence that male rats exposed to high levels of radio frequency radiation like that used in 2G and 3G cell phones developed cancerous heart tumors, according to final reports released today.

2 Nov 2018

Illumina signs agreement to acquire Pacific Biosciences

Illumina, Inc. and Pacific Biosciences today announced they have signed an agreement for Illumina to acquire Pacific Biosciences at a price of $8.00 per Pacific Biosciences share in an all-cash transaction.

2 Nov 2018

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

The Huntington's Disease Regulatory Science Consortium, launched in March 2018 by the Critical Path Institute and CHDI Foundation, today, along with the Clinical Data Interchange Standards Consortium, announce the open availability of a newly developed Huntington's Disease Therapeutic Area User Guide

2 Nov 2018

DNA News and Research

Further Reading

CDK2 protein plays key role in heart damage caused by doxorubicin, finds study

New open source decision support tool could help clinicians chose chemotherapy drugs

Study elucidates genetic causes of severe cardiomyopathies in children

Mutant p53 protein 'tackles' DNA guardian to drive tumor development

Researchers develop first chemical inhibitors for treatment of acute myeloid leukemia

Scientists make strides in developing liquid biopsies for detecting brain tumor DNA

Experts study antibiotic resistance in recycled water

U.S. Department of Defense grants 'Impact Award' to explore therapeutic options against advanced prostate cancer

Scientists discover new details about UHRF1 protein

Scientists investigate how broad-spectrum antibiotic therapy affects interaction of gut bacteria

Researchers identify pathway to resolve allergic asthma

Cancer risk linked to mobile phone radiation in rats but cannot be extrapolated to humans

New research explains how large virus shells are formed

Slime in showerheads could harbour dangerous lung bacteria finds study

Study offers new hope to patients with rare brain cancer

Genetic factors linked to obesity may lower metabolic risk

New way of identifying potential cancer drugs could streamline development of therapies

Male rats exposed to high levels of radio frequency radiation develop cancer, finds study

Illumina signs agreement to acquire Pacific Biosciences

C-Path, CHDI and CDISC announce availability of Huntington's Disease Therapeutic Area User Guide

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