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New understanding of fetal hemoglobin regulation in patients with sickle cell disease

Although sickle cell disease is a single-gene disorder, its symptoms are highly variable. In a study published online July 14 by the Proceedings of the National Academy of Sciences, scientists at Children's Hospital Boston and the Dana Farber Cancer Institute (DFCI), in collaboration with the Broad Institute of MIT and Harvard, report five gene variants that could potentially be helpful in predicting sickle cell disease severity, perhaps even leading to better treatment approaches in the future.

15 Jul 2008

"Smothered" genes combine with mutations to yield poor out come in cancer patients

Johns Hopkins Kimmel Cancer Center researchers have identified a set of genes in breast and colon cancers with a deadly combination of traditional mutations and "smothered" gene activity that may result in poor outcomes for patients.

15 Jul 2008

Low-sodium advice for asthmatics should be taken with a pinch of salt

Following a low-sodium diet does not appear to have any appreciable impact on asthma control, according to new research.

15 Jul 2008

Diabetes could be a hidden condition for heart disease patients

Researchers at the University of Warwick have discovered diabetes could be a hidden condition for some patients with coronary heart disease.

15 Jul 2008

New technology revolutionizing drug discovery

The National Science Foundation has awarded Weill Cornell Medical College researcher Dr. Scott Blanchard its prestigious Career Award, recognizing his groundbreaking work in cell biology -- work that is poised to revolutionize research for the next generation of young scientists.

15 Jul 2008

New ways of exploiting medicinal uses of cannabis

Research exploring new ways of exploiting the full medicinal uses of cannabis while avoiding unwanted side-effects will be presented to pharmacologists Tuesday, 15 July by leading scientists attending the Federation of European Pharmacological Societies Congress, EPHAR 2008.

From The University of Manchester 15 Jul 2008

Quick formula could forecast which cancers chemo could kill

Researchers at the University of Rochester Medical Center have coined a simple formula that predicts how well a certain chemotherapy will work for targeting brain and other nervous system cancers. The formula, which publishes mid-July in Cancer Chemotherapy and Pharmacology, is pegged to two important proteins that compose such hard-to-kill tumors - one of which, ironically, makes them so drug-resistant in the first place.

15 Jul 2008

Variations in the serotonin transporter gene may determine who responds best to antidepressant

A new Mayo Clinic study shows that variations in the serotonin transporter gene could explain why some people with depression respond better than others to treatment with citalopram (Celexa), an antidepressant medication.

14 Jul 2008

Hip or knee replacement surgery may improve osteoarthritis symptoms in older adults

Older adults who have hip or knee replacement surgery for severe osteoarthritis may take several weeks to recover but appear to have excellent long-term outcomes, according to a report in the July 14 issue of Archives of Internal Medicine.

14 Jul 2008

Certain communication skills can help physicians increase the efficiency of their time with patients during office visits

With their waiting rooms crowded and exam rooms full, many physicians say they are too busy to be good communicators. Those who study physician time-management think otherwise. Certain communication skills can foster efficiency and effectiveness during an office visit without sacrificing rapport with patients, according to researchers at the University of Washington (UW) and the University of Rochester.

14 Jul 2008

Huntington's disease brain damage linked to overactive immune response in the bloodstream

The damage to brain tissue seen in Huntington's disease may be caused by an overactive immune response in the bloodstream and the brain, according to new findings from two teams of researchers at the University of Washington in Seattle and University College London. The findings will be published online July 14 in the Journal of Experimental Medicine.

14 Jul 2008

Prehypertension in adults aged 18 to 30 common and associated with coronary atherosclerosis

Prehypertension during young adulthood is common and is associated with subsequent coronary atherosclerosis, according to a study published in today's issue of Annals of Internal Medicine.

14 Jul 2008

Researchers step closer to delivering cancer-killing drugs to pediatric brain tumors

An interdisciplinary team of researchers at Washington University in St. Louis, led by Karen L. Wooley, Ph.D., James S. McDonnell Distinguished University Professor in Arts & Sciences, is a step closer to delivering cancer-killing drugs to pediatric brain tumors, similar to the tumor that Senator Ted Kennedy is suffering from.

14 Jul 2008

Nuclear stress test detects problems in left ventricle

A less invasive test commonly used to diagnose coronary disease also may be used to detect one of the leading causes of heart failure, say researchers at the Medical College of Georgia.

14 Jul 2008

Physical exercise may prevent brain shrinkage in early Alzheimer's

Mild Alzheimer's disease patients with higher physical fitness had larger brains compared to mild Alzheimer's patients with lower physical fitness, according to a study published in the July 15, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2008

Older patients more satisfied with care when accompanied to medical visits

A study by researchers at the Johns Hopkins Bloomberg School of Public Health found that 38 percent of Medicare beneficiaries are accompanied to routine medical visits.

14 Jul 2008

Allergy to road traffic

Allergic diseases appear more often in children who grow up near busy roads. This is the result of a study of several thousand children, now published in the American Journal of Respiratory and Critical Care Medicine.

14 Jul 2008

Heart death risk cut by early warning drugs tests

The likelihood of people dying because their medication has a side effect that affects the electrical activity of the heart is being reduced - thanks to a better understanding of why this happens and the development of tests to predict it.

From The University of Manchester 14 Jul 2008

Obesity ranks as top health concern for kids, poll finds

As children's waistlines continue to grow, so have concerns about childhood obesity. According to a report released today by the University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health, childhood obesity is now the No. 1 health concern for kids in 2008, topping smoking and drug abuse. In 2007, childhood obesity ranked third among parents' top 10 overall health concerns for kids.

14 Jul 2008

Nicotine clues for dementia treatment

A team of London scientists have found clues for the potentially therapeutic benefits of nicotine on learning, memory and attention while minimising the risk of addiction. The research announced in Geneva Monday will assist the search for new drugs for dementia.

14 Jul 2008

Medicine News and Research

New understanding of fetal hemoglobin regulation in patients with sickle cell disease

"Smothered" genes combine with mutations to yield poor out come in cancer patients

Low-sodium advice for asthmatics should be taken with a pinch of salt

Diabetes could be a hidden condition for heart disease patients

New technology revolutionizing drug discovery

New ways of exploiting medicinal uses of cannabis

Quick formula could forecast which cancers chemo could kill

Variations in the serotonin transporter gene may determine who responds best to antidepressant

Hip or knee replacement surgery may improve osteoarthritis symptoms in older adults

Certain communication skills can help physicians increase the efficiency of their time with patients during office visits

Huntington's disease brain damage linked to overactive immune response in the bloodstream

Prehypertension in adults aged 18 to 30 common and associated with coronary atherosclerosis

Researchers step closer to delivering cancer-killing drugs to pediatric brain tumors

Nuclear stress test detects problems in left ventricle

Physical exercise may prevent brain shrinkage in early Alzheimer's

Older patients more satisfied with care when accompanied to medical visits

Allergy to road traffic

Heart death risk cut by early warning drugs tests

Obesity ranks as top health concern for kids, poll finds

Nicotine clues for dementia treatment

Everything there is to know about biosimilars eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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