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Clinical trial to evaluate effectiveness of biologic augmentation in ACL reconstruction surgery

Marshall University Joan C. Edwards School of Medicine is initiating a new clinical trial to evaluate the efficacy and safety of using biologic augmentation during anterior cruciate ligament, or ACL, reconstruction surgery.

5 Nov 2019

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

The Human Immune Monitoring Center at the Icahn School of Medicine at Mount Sinai will apply cutting-edge high-throughput technologies to evaluate the therapeutic effects of Libtayo (cemiplimab-rwlc), a PD-1 antibody blockade developed by biotechnology company Regeneron Pharmaceuticals, Inc and Sanofi.

5 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

The use of nanoparticles to deliver a drug into specific nerve cells has resulted in significantly improved pain relief.

5 Nov 2019

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

The University of Texas MD Anderson Cancer Center and Takeda Pharmaceutical Company Limited today announced an exclusive license agreement and research agreement to develop cord blood-derived chimeric antigen receptor-directed natural killer (CAR NK)-cell therapies, 'armored' with IL-15, for the treatment of B-cell malignancies and other cancers.

5 Nov 2019

Humanizing cell cultures

Today we know the function and metabolism of any mammalian cell depends on its environment. Such cells have long been cultured under conditions consisting of a basal medium with added nutritional serum. This, however, is not an accurate replica of the cell’s environment within the human body.

5 Nov 2019

Researchers develop new type of transposase protein with improved biochemical properties

The team, comprising researchers from the European Molecular Biology Laboratory, the Universitätsklinikum Würzburg and the Paul-Ehrlich-Institut, managed to design a new variant of the Sleeping Beauty transposase with dramatically improved biochemical properties.

4 Nov 2019

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

An international team of researchers has used nanoparticles to deliver a drug- one that previously failed in clinical trials for pain- into specific compartments of nerve cells, dramatically increasing its ability to treat pain in mice and rats.

4 Nov 2019

UK aims to lead with cutting-edge radiation therapy

The UK is all set to launch its run into the future as the undisputed leader in the field of personalized and effective radiation therapy. The proposal is undergirded by a whopping £56 million, which will be used to set up and fund advanced radiation therapy research by a new collaborative setup, Cancer Research UK RadNet, over five years. This is the largest sum ever invested by this organization into radiotherapy research.

4 Nov 2019

Latest stroke prevention strategies to be showcased at SVIN 2019 Annual Meeting

The Society of Vascular and Interventional Neurology is committed to improving stroke prevention strategies as well as expanding access to the most impactful and modern acute stroke treatments to our patients worldwide.

4 Nov 2019

Moffitt study discovers cellular mechanism controlling tumor cell recognition by immune cells

Immunotherapy has become a standard treatment approach for several types of cancer, including melanoma.

1 Nov 2019

Correlates of HIV risk associated with decrease in disease transmission, study confirms

Immune responses that are associated with a decreased risk of infection are called correlates of protection.

1 Nov 2019

Switching to greener asthma inhalers would reduce carbon footprint

Environmentalists now have a new cause to take up – the metered dose inhalers (MDIs) used by asthmatic patients to control their airway spasm.

31 Oct 2019

Increasing anti-tumor activity of compound extracted from an Amazon plant

Researchers in Brazil have prepared modified forms of the alkaloids produced by Uncaria guianensis, a woody vine native to the Amazon Rainforest.

31 Oct 2019

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Sometimes vaccines need a little help to protect people against infectious diseases.

31 Oct 2019

Research forum to present results of novel anti-obesity medications

Rhythm Pharmaceuticals and Novartis will present findings from the latest stages of clinical evaluation of new anti-obesity medications during a special late-breaking research forum titled "Emerging Pharmacological Anti-obesity Therapies."

31 Oct 2019

New contrast agent improves MRI diagnosis of early liver fibrosis

A new compound has been invented to bind to liver cells that are in the early stages of damage, thus making it easier to pick them up using MRI (magnetic resonance imaging).

30 Oct 2019

Avocados may hold the key to managing obesity and preventing diabetes

Your guacamole may hold the key to managing obesity and helping delay or prevent diabetes, according to a new study by a University of Guelph research team.

30 Oct 2019

New grant funds innovative approach to bladder cancer treatment

The San Antonio Medical Foundation has awarded Texas Biomedical Research Institute Professor Jordi B. Torrelles, Ph.D., with a $173,000 grant to study a modified Mycobacterium bovis Bacillus Calmette et Guérin (BCG) vaccine shown to have promise for treating bladder cancer.

30 Oct 2019

Congressional briefing on moving away from dog studies in the development of new medicines

At a congressional briefing Tuesday, Vanda Pharmaceuticals, the Physicians Committee for Responsible Medicine, and the Humane Society of the United States urged Congress to task the U.S. Food and Drug Administration with moving away from dog studies and other animal testing in the development of new medicines.

30 Oct 2019

Efficacy News and Research

Clinical trial to evaluate effectiveness of biologic augmentation in ACL reconstruction surgery

HIMC at Mount Sinai to evaluate therapeutic effects of novel cancer immunotherapy

The Achilles heel of APC-mutated colon tumors identified

Researchers successfully treat pain using nanoparticles to deliver a non-opioid medication

MD Anderson and Takeda announce agreement to develop off-the-shelf CAR NK-cell therapy platform

Humanizing cell cultures

Researchers develop new type of transposase protein with improved biochemical properties

Nanoparticle drug delivery enhances and prolongs pain relief in animal models

UK aims to lead with cutting-edge radiation therapy

Latest stroke prevention strategies to be showcased at SVIN 2019 Annual Meeting

Moffitt study discovers cellular mechanism controlling tumor cell recognition by immune cells

Correlates of HIV risk associated with decrease in disease transmission, study confirms

Switching to greener asthma inhalers would reduce carbon footprint

Increasing anti-tumor activity of compound extracted from an Amazon plant

OHSU receives $2.1 million to develop new vaccine additives for tropical viruses

Research forum to present results of novel anti-obesity medications

New contrast agent improves MRI diagnosis of early liver fibrosis

Avocados may hold the key to managing obesity and preventing diabetes

New grant funds innovative approach to bladder cancer treatment

Congressional briefing on moving away from dog studies in the development of new medicines

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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