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Improved Cas9 enzyme reduces chance of off-target CRISPR mutations

Genomics experts have discovered that when guide RNAs (gRNA) are designed properly, the risk of off-target mutations induced by the cas9 enzyme is very rare.

30 Oct 2019

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

November is National Pancreatic Cancer Awareness month. This year alone, more than 56,000 Americans will be diagnosed with pancreatic cancer. Pancreatic tumors are particularly aggressive and hard to treat "due to a mutational profile that makes it resistant to therapies that work better for other tumor types," explains Angela Alistar, MD, medical director of GI Oncology at Morristown Medical Center.

30 Oct 2019

Youth with psychosis spectrum disorders have distinct brain region alterations

Psychotic spectrum (PS) disorders are characterized by abnormalities in beliefs, perceptions and behavior, but how these disorders manifest themselves in earlier development stages is largely unknown.

30 Oct 2019

New TB vaccine: mid-phase trials confirm safety, long-term prevention

A new study published on October 29, 2019, in the New England Journal of Medicine, reports a new vaccine which could change the face of tuberculosis prevention. The disease kills 1.5 million people worldwide each year.

30 Oct 2019

Homeopathy quackery - NHS leaders urge caution

A new controversy is ripe, what with the head of the UK National Health Service (NHS), Simon Stevens, publicly expressing his “serious concerns” about the “fundamentally flawed” practice of homeopathy.

29 Oct 2019

Bortezomib drug helps re-balance disrupted muscle growth, prevent contractures

When children experience brachial plexus injury at birth, or are born with cerebral palsy, some of the most disabling problems that follow are muscle contractures, or tightness of muscles, that severely restrict limb function.

29 Oct 2019

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Researchers are making great strides toward developing gene-based strategies to treat a variety of inherited neurometabolic diseases characterized by severe neurological involvement.

29 Oct 2019

Gabapentinoid medications increasingly prescribed off-label for adults with cancer

Between 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications -- gabapentin and pregabalin -- to adults with cancer saw a two-fold increase, a University of Michigan Rogel Cancer Center study has found.

29 Oct 2019

KAUST researchers one step closer to understanding brain function

Researchers at King Abdullah University of Science and Technology (KAUST) are officially one-step closer to understanding the brain and its function.

29 Oct 2019

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate payloads, today announced data demonstrating the potent efficacy and favorable toxicity profile of a reduced potency analogue from its Pyridinobenzodiazepine ADC payload platform in solid tumor models.

From Pheon Therapeutics 29 Oct 2019

NYU researcher awarded $1.7 million NIH grant to optimize cancer treatment

Weiqiang Chen, assistant professor of biomedical engineering and mechanical and aerospace engineering at the NYU Tandon School of Engineering, has been awarded the Maximizing Investigators' Research Award (R35) from the National Institute of General Medical Sciences, a division of the National Institutes of Health.

29 Oct 2019

Novel antibodies could provide a universal flu vaccine

Now, a new study published in the journal Science on October 25, 2019, reports on a set of three novel antibodies that bind to another type of viral cell surface antigen called neuraminidase (NA) that is necessary for viral replication.

28 Oct 2019

WHO expert panel discusses digital technology in public health

For the first time ever, the World Health Organization (WHO) has brought together experts in the domain of public health to discuss how digital health technologies can help achieve its goals of global health. The panel, called the Digital Health Technical Advisory Group, discussed a wide range of topics from how data is dealt with, through issues of cost-effectiveness and evidence-based decision making, to making digital health a widely available and ethically bound solution.

28 Oct 2019

Work in progress on medicine for treatment of ulcerative colitis

IKBFU center for clinical research scientists have participated in the international VARSITY clinical research. It's the world's first research aimed at finding the most effective drug among anti-inflammatory ones for the treatment of ulcerative colitis.

28 Oct 2019

Non-biologic simulators could prove to be better alternative for training plastic surgeons in microsurgery

Microsurgery is an intricate and challenging surgical technique that involves using miniature instruments and sutures as fine as a hair strand aided by sophisticated microscopes.

25 Oct 2019

New injectable formula to treat joint inflammation has sustained effect for ten days

Thanks to a new injectable formula, Brazilian researchers have succeeded in enhancing the efficacy and prolonging the duration of action of a drug commonly used to treat joint inflammation.

25 Oct 2019

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Atlantic Health System is treating patients in a new Phase 2 clinical trial of CAR T-cell therapy at Morristown Medical Center. A select number of sites across the U.S. are involved in this study, which is done on an outpatient basis.

25 Oct 2019

Survey shows positive link between infection prevention certification and ASP comprehensiveness

Nearly half of all nursing homes do not have adequately trained infection prevention staff and their efforts to combat the over prescription of antibiotics are suffering as a result, according to a new study in the American Journal of Infection Control, the journal of the Association for Professionals in Infection Control and Epidemiology, published by Elsevier.

25 Oct 2019

Optimal implementation of existing, new interventions essential to end HIV pandemic

Optimal implementation of existing HIV prevention and treatment tools and continued development of new interventions are essential to ending the HIV pandemic, National Institutes of Health experts write in a commentary Clinical Infectious Diseases.

24 Oct 2019

Universal influenza vaccine developed at Cornell is set for human clinical trials

A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Efficacy News and Research

Improved Cas9 enzyme reduces chance of off-target CRISPR mutations

Atlantic Health System Cancer Care enrolling patients in five pancreatic cancer studies

Youth with psychosis spectrum disorders have distinct brain region alterations

New TB vaccine: mid-phase trials confirm safety, long-term prevention

Homeopathy quackery - NHS leaders urge caution

Bortezomib drug helps re-balance disrupted muscle growth, prevent contractures

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Gabapentinoid medications increasingly prescribed off-label for adults with cancer

KAUST researchers one step closer to understanding brain function

Femtogenix announces new data on ADCs containing reduced potency payloads in solid tumor models

NYU researcher awarded $1.7 million NIH grant to optimize cancer treatment

Novel antibodies could provide a universal flu vaccine

WHO expert panel discusses digital technology in public health

Work in progress on medicine for treatment of ulcerative colitis

Non-biologic simulators could prove to be better alternative for training plastic surgeons in microsurgery

New injectable formula to treat joint inflammation has sustained effect for ten days

Phase 2 clinical trial of CAR T-cell therapy starts at Atlantic Health System

Survey shows positive link between infection prevention certification and ASP comprehensiveness

Optimal implementation of existing, new interventions essential to end HIV pandemic

Universal influenza vaccine developed at Cornell is set for human clinical trials

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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