Kidney News and Research

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Affymax, Takeda's peginesatide Phase 3 data in dialysis patient to be presented at NKF meeting

Affymax, Inc. and Takeda Global Research & Development Center, Inc., U.S., today announced multiple posters on peginesatide have been accepted for presentation at the National Kidney Foundation 2011 Spring Clinical Meeting taking place April 26-30, 2011 in Las Vegas, Nevada.

24 Mar 2011

Sequencing mouse cancer genome reveals mutations driving cancer in humans

Scientists who pioneered sequencing the genomes of cancer patients to find novel genetic changes at the root of the disease now have turned their attention to a laboratory workhorse — a mouse.

24 Mar 2011

New study: Prostate and breast cancer usually recur in bone

Like bad neighbors who decide to go wreck another community, prostate and breast cancer usually recur in the bone, according to a new University of Michigan study.

24 Mar 2011

MicroRNAs may play a key role in future medicine

Since their discovery in the 1990s, microRNAs have proven to play a complex role in normal and abnormal functioning of many organ systems. In the April issue of Translational Research, entitled "MicroRNAs: A Potential New Frontier for Medicine," an international group of medical experts explores several themes related to our current understanding of microRNAs and the role they may play in the future of medicine.

24 Mar 2011

New insights into cancer genome may lead to designer drugs for myeloma

Patients with myeloma could benefit from ‘designer’ drugs in the future after new genome-mapping technology has allowed scientists to identify a full genetic blueprint of the mutations which drive the bone marrow cancer.

23 Mar 2011

Genetic errors in women linked to increased risk of preeclampsia

Scientists have identified genetic errors in women with autoimmune diseases that increase the risk of preeclampsia, a potentially life-threatening condition that occurs in 10 percent of all pregnancies.

23 Mar 2011

NeoTract initiates patient enrollment for UroLift System trial to treat prostrate cancer

NeoTract, Inc. a medical device company focused on developing urology devices, today announced that the first U.S. patients have been enrolled in a multinational trial of its UroLift® System at Western Urological Clinic in Salt Lake City, Utah.

23 Mar 2011

Study to measure lower pressure's impact on kidney disease, cognitive function

Georgia Health Sciences University is enrolling patients in a federally funded study to determine if a lower blood pressure reduces the progression of kidney disease.

22 Mar 2011

High sodium intake may increase risk of heart disease, stroke, kidney problem

Taking in too much sodium may turn out to be quite a salty situation. In fact, according to the Centers for Disease Control and Prevention, in 2010 high blood pressure cost the United States $76.6 billion in health care services, medications, and missed days of work.

22 Mar 2011

NYC expands YMCA's Diabetes Prevention Program to help adults avoid disease consequences

The YMCA of Greater New York today announced the New York City expansion of the YMCA's Diabetes Prevention Program, a 16-session group behavior change class that helps people at high risk for developing type 2 diabetes prevent the disease through healthy eating, increased activity and other positive lifestyle changes.

22 Mar 2011

ACE, ARB combination therapy may increase risk of kidney failure, death

Elderly patients prescribed combination angiotensin converting enzyme inhibitors and angiotensin receptor blockers had a higher risk of kidney failure and death, according to a study published in CMAJ.

22 Mar 2011

Researchers review patient outcomes from full, partial organ removal for kidney cancer

Patients with kidney cancer who had their entire organ removed were more likely to have more renal complications and poorer health after surgery, compared to those who had only part of their kidney removed, a study has shown.

19 Mar 2011

Olympus offers new stones retrieval products

Over the last years, the equipment for endoscopy and training of ureteroscopy has improved significantly. The shift from ESWL to ureteroscopy is evident.

From Evident Corporation - Life Sciences 18 Mar 2011

Medicare officials signal no payment changes on anemia drugs

Medicare officials signaled Wednesday that they will not change a payment policy for biotech drugs made by Amgen and Johnson & Johnson when they are used to treat anemia in kidney disease patients, despite data suggesting heart risks for those patients.

18 Mar 2011

U-M researcher endorses new concepts designed to improve kidney allocation

Providing kidney transplants to patients with the best probability of longer survival would reduce repeat transplant operations and improve life span after kidney transplant, says a U-M researcher in a commentary published in the New England Journal of Medicine March 16.

18 Mar 2011

Scientists receive £5million EU grant to identify gene targets for kidney cancer treatment

An international consortium led by scientists from the Cancer Research UK London Research Institute, The Royal Marsden Hospital and the Technical University of Denmark has been granted nearly £5million by the European Union to identify gene targets for personalised treatment for kidney cancer patients.

18 Mar 2011

FibroGen, Astellas advance FG-4592 to phase 2b development for treatment of anemia in chronic kidney disease

FibroGen, Inc., today announced that FibroGen and partner Astellas Pharma Inc. advanced FG-4592 (Astellas designation ASP1517), an investigational anemia therapy, to phase 2b development for treatment of anemia in chronic kidney disease (CKD) patients on dialysis and not on dialysis.

18 Mar 2011

Researchers discover 3-D structure of key biological receptor

Researchers have solved the three-dimensional structure of a key biological receptor. The finding has the potential to speed drug discovery in many areas, from arthritis to respiratory disorders to wound healing, because it enables chemists to better examine and design molecules for use in experimental drugs.

16 Mar 2011

New study on how epoxyeicosatrienoic acids protect kidneys

Researchers at Georgia Health Sciences University are studying whether inhibiting an enzyme that reduces levels of a protective metabolite could halt the progression of diabetic nephropathy, or kidney disease resulting from diabetes.

16 Mar 2011

Hospitals with higher diagnosis frequency for chronic conditions have lower case-fatality rate

An examination of data for more than 5 million Medicare beneficiaries finds that hospital regions that have a greater frequency of diagnoses have a lower case-fatality rate for chronic conditions such as coronary artery disease and kidney failure, according to a study in the March 16 issue of JAMA.

16 Mar 2011