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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Blood methylome offers clues to schizophrenia

Researchers show that a methylome-wide association study of the blood can provide a glimpse of past environmental insults that may contribute to the development of schizophrenia.

22 Jan 2014

Study ultimately could lead to development of screening test for diagnosing bladder cancer

Findings from a Loyola University Medical Center study ultimately could lead to tests to screen for and diagnose bladder cancer.

22 Jan 2014

Italian biochemist receives Louis-Jeantet Prize for Medicine for the year 2014

The 2014 LOUIS-JEANTET PRIZE FOR MEDICINE is awarded to the Italian biochemist Elena Conti, Director of the Department of Structural Cell Biology at the Max-Planck Institute of Biochemistry in Munich (Germany) and to Denis Le Bihan, the French medical doctor, physicist and Director of NeuroSpin, an institute at the French Nuclear and Renewable Energy Commission (CEA) at Saclay near Paris.

22 Jan 2014

Researchers suggest new targets may provide druggable alternatives to Ewing's Sarcoma

Ewing's Sarcoma is an aggressive pediatric cancer, most commonly caused by the improper fusion of the gene EWS with the gene FLI1. Though the cause has long been known, therapeutic targeting of this fusion has to date proven very difficult.

22 Jan 2014

European Commission approves ViiV Healthcare's Tivicay for treatment of HIV infected adults

ViiV Healthcare today announced that the European Commission has approved Tivicay (dolutegravir), an integrase inhibitor, for use in combination with other anti-retroviral medicinal products for the treatment of HIV infected adults and adolescents above 12 years of age.

21 Jan 2014

Illumina inks multi-year supply agreement with LabCorp

Illumina, Inc. today announced it has entered into a multi-year supply agreement with Laboratory Corporation of America Holdings. The agreement gives LabCorp expanded rights to use Illumina next-generation sequencing and microarray equipment and supplies to develop, validate and introduce laboratory-developed tests to clinicians in the United States and Canada.

From Illumina, Inc. 21 Jan 2014

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Normally, tissue injury triggers a mechanism in cells that tries to repair damaged tissue and restore the skin to a normal, or homeostatic state. Errors in this process can give rise to various problems, such as chronic inflammation, which is a known cause of certain cancers.

21 Jan 2014

Breakthrough technology could provide new approach for treatment of chronic wounds

A team of researchers led by an NIBIB grantee at Vanderbilt University has created a biodegradable scaffold that enables sustained, local delivery of gene-silencing factors called siRNA to promote tissue regeneration. The team recently used the scaffold to successfully deliver siRNA to mice in order to locally silence a gene normally responsible for inhibiting blood vessel formation.

20 Jan 2014

Tumor profiling study of colorectal cancer to be presented at 2014 Gastrointestinal Cancers Symposium

Caris Life Sciences, a leading biosciences company focused on fulfilling the promise of personalized medicine, will present a large international tumor profiling study of colorectal cancer at the 2014 Gastrointestinal Cancers Symposium this week in San Francisco, Calif. With more than 7,000 patients comprehensively profiled by Caris Molecular Intelligence, this study represents the largest, multi-national analysis in a single laboratory setting of the main molecular anomalies in colorectal cancer.

18 Jan 2014

Researchers managed to replicate human pancreatic beta cells in mouse model

Klaus Kaestner, PhD, professor of Genetics and postdoctoral fellow Dana Avrahami, PhD, from the Perelman School of Medicine, University of Pennsylvania, published a study this week in the Journal of Clinical Investigation, with colleague Benjamin Glaser, MD, from the Hadassah-Hebrew University Medical Center, Jerusalem, and colleagues. In this study, they were able to replicate human pancreatic beta cells - the cells in our body that produce the critical hormone insulin - in a mouse model in which donor cells were transplanted. The newly replicated cells retained features of mature beta cells and showed a physiological response to glucose.

17 Jan 2014

RNA sequencing unlocks bipolar secrets

An RNA sequencing study of patients with bipolar disorder has shown altered expression of genes and transcripts, including those involved in neuroplasticity and circadian rhythms.

16 Jan 2014

BMH-21 chemical compound has ability to shut down a common cancer process

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

15 Jan 2014

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Researchers at the University of Massachusetts Medical School (UMMS) have been commissioned by the Alpha-1 Project (TAP) to develop a PiZ antibody. The antibody will be used to track the presence of mutant alpha-1 PiZ protein in human blood serum, an essential tool in testing potential therapies for Alpha-1 Antitrypsin Deficiency (Alpha-1).

13 Jan 2014

Life Technologies, Quest Diagnostics sign multi-year license and supply agreement

Life Technologies has completed a multi-year license and supply agreement with Quest Diagnostics, the world's leading provider of diagnostic information services, that gives Quest rights to develop molecular tests on the Ion Torrent next-generation sequencing platform. Under the agreement, Quest may use the platform and related consumables to independently develop new tests for numerous areas of their business.

From Quest Diagnostics 10 Jan 2014

Researchers reveal newest weapon to visualize shape and motion of RNA

Qi Zhang sees himself as a warrior. In his lab at the University of North Carolina at Chapel Hill, he wages war on genetic diseases such as cancer and heart disease on a battlefield measured with single atoms.

10 Jan 2014

Illumina signs multi-year licensing agreement with Quest Diagnostics

Illumina, Inc. today announced it has entered into a multi-year licensing agreement with Quest Diagnostics, the world's leading provider of diagnostic information services, related to the use of Illumina's next-generation sequencing technology for clinical laboratory testing.

From Illumina, Inc. 9 Jan 2014

UMMS assistant professor recognized with Presidential Early Career Award for Scientists and Engineers

University of Massachusetts Medical School Assistant Professor Thomas G. Fazzio, PhD, was recognized as a rising scientific star by President Obama with a Presidential Early Career Award for Scientists and Engineers.

9 Jan 2014

Rexahn Pharmaceuticals initiates RX-3117 Phase Ib trial in cancer patients with solid tumors

Rexahn Pharmaceuticals, Inc. a clinical stage biopharmaceutical company, announced today the initiation of a Phase Ib clinical trial to study the safety and efficacy of RX-3117 in cancer patients with solid tumors.

9 Jan 2014

MicroRNA biomarker shows promise in predicting treatment response of ovarian cancer

Researchers at Case Western Reserve University have identified a microRNA biomarker that shows promise in predicting treatment response in the most common form of ovarian cancer - a breakthrough that has the potential to improve outcomes for patients with the disease.

9 Jan 2014

Researchers develop new, safer and noninvasive diagnostic technique for ulcers

Doctors may soon be able to diagnose stomach ulcers without taking tissue samples from the stomach. Researchers from the University of Southern Denmark now report to have developed a new, safer and noninvasive diagnostic technique for ulcers.

8 Jan 2014

RNA News and Research

Further Reading

Blood methylome offers clues to schizophrenia

Study ultimately could lead to development of screening test for diagnosing bladder cancer

Italian biochemist receives Louis-Jeantet Prize for Medicine for the year 2014

Researchers suggest new targets may provide druggable alternatives to Ewing's Sarcoma

European Commission approves ViiV Healthcare's Tivicay for treatment of HIV infected adults

Illumina inks multi-year supply agreement with LabCorp

Splicing factor SRSF6 promotes hyperplasia of sensitized skin

Breakthrough technology could provide new approach for treatment of chronic wounds

Tumor profiling study of colorectal cancer to be presented at 2014 Gastrointestinal Cancers Symposium

Researchers managed to replicate human pancreatic beta cells in mouse model

RNA sequencing unlocks bipolar secrets

BMH-21 chemical compound has ability to shut down a common cancer process

UMMS researchers commissioned by Alpha-1 Project to develop PiZ antibody

Life Technologies, Quest Diagnostics sign multi-year license and supply agreement

Researchers reveal newest weapon to visualize shape and motion of RNA

Illumina signs multi-year licensing agreement with Quest Diagnostics

UMMS assistant professor recognized with Presidential Early Career Award for Scientists and Engineers

Rexahn Pharmaceuticals initiates RX-3117 Phase Ib trial in cancer patients with solid tumors

MicroRNA biomarker shows promise in predicting treatment response of ovarian cancer

Researchers develop new, safer and noninvasive diagnostic technique for ulcers

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