Efficacy News and Research

RSS

Vaccine for Lassa fever set to enter clinical testing in humans

There is currently no vaccine for the Lassa arenavirus, which causes Lassa fever. This hemorrhagic fever, endemic in West Africa, infects up to 300,000 people each year.

24 Oct 2019

Kidney Health Initiative to study patient preferences for novel renal replacement therapy devices

The US Food and Drug Administration has awarded a contract to the Kidney Health Initiative to study patient preferences for innovative renal replacement therapy devices.

24 Oct 2019

Risk factors for unemployment with multiple sclerosis vary by age, study finds

A recent study by Kessler Foundation researchers explored numerous factors that contribute to the high unemployment rate among individuals of different ages with multiple sclerosis.

24 Oct 2019

Researchers discover unexpected role of mTORC2 protein in colorectal cancer

New results from researchers at MedUni Vienna's Center for Pathobiochemistry and Genetics show that a protein called mTORC2, which is the target of newly developed cancer drugs, is not even active in colorectal cancer. mTORC2 activity was only found in certain immune cells, which actually need this protein to fight cancer cells.

24 Oct 2019

Cooperative research center at LLNL aims to develop vaccines for chlamydia

A cooperative research center that aims to develop vaccines for chlamydia has been established by the National Institutes of Health at Lawrence Livermore National Laboratory.

24 Oct 2019

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

Neuroscientists at Georgetown University Medical Center say they have developed and tested an agent that reduces the buildup of toxic proteins in animal models of both Parkinson's and Alzheimer's diseases, and improves cognitive and motor behavior.

23 Oct 2019

UAB researchers awarded grant to study a vaccine for gonorrhea

University of Alabama at Birmingham researchers have been awarded a three-year contract with a total potential amount of $10 million to study the efficacy of the vaccine Bexsero - already licensed to prevent meningitis - in protecting vulnerable populations from infection with the bacteria that causes gonorrhea.

23 Oct 2019

Discovery reveals why newer PD-1 targeted therapies sometimes fail

Researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute report a discovery that helps scientists understand why some tumors lack immune cell infiltration and are therefore unresponsive to newer PD-1 targeted therapies.

23 Oct 2019

Q-Suite Motor Assessment Tool helps detect subtle motor abnormalities in children

In clinical trials of adults with Huntington's disease (HD) the Q-Suite Motor Assessment Tool (Q-Motor) has proven to be helpful to detect and quantitate subtle motor abnormalities.

22 Oct 2019

Biogen to pursue FDA regulatory approval for investigational drug aducanumab

On behalf of the more than 5 million Americans living with Alzheimer's and their family members, the Alzheimer's Association is encouraged to learn that Biogen will pursue regulatory approval from the FDA for the investigational drug aducanumab based on Phase 3 clinical trial results from the EMERGE and ENGAGE studies, and other related data, after finding a reduction of cognitive and functional decline in people taking the high dose.

22 Oct 2019

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Jennifer J. Lentz, PhD, Associate Professor at LSU Health New Orleans Neuroscience Center of Excellence and Departments of Otorhinolaryngology, Genetics and Ophthalmology, in collaboration with Robert K. Koenekoop MD, PhD and Professor of Pediatric Surgery, Human Genetics and Ophthalmology at McGill University in Montreal, Quebec, Canada, has been awarded a $1.74 million USD grant to advance research on Usher syndrome.

22 Oct 2019

Researchers elucidate properties of blood factor involved in weight loss and aging

Aging is a process that affects all functions of the human body, particularly brain function. However, aging can be delayed through lifestyle changes (physical exercise, restricting calorie intake, etc.).

22 Oct 2019

Oncolytics Biotech and PrECOG collaborate to study metastatic breast cancer

Oncolytics Biotech Inc. , currently developing pelareorep, an intravenously delivered immuno-oncolytic virus, and PrECOG LLC, a leading cancer research network, today announced their collaboration in which PrECOG will run the BRACELET-1 (PrE0113) study.

22 Oct 2019

Creatine powers fight against cancer, improves efficacy of immunotherapies

The immune system functions as the body’s defense against pathogens and harmful substances, including cancer cells. They protect the body against potential harm. In cases of cancer, though the body tries to fight the tumor cells, they may become too aggressive for the immune system to eradicate.

21 Oct 2019

New findings demonstrate how subtle social interactions can impact clinical outcomes

If a doctor expects a treatment to be successful, a patient may experience less pain and have better outcomes, according to a new Dartmouth study published in Nature Human Behaviour.

21 Oct 2019

Ebola virus vaccine still effective against the infection even in low concentrations

The Ebola virus (EBOV), variant Makona, was the causative agent of the 2014-2016 West African epidemic that took over 11,000 lives and infected nearly 30,000 people. But with the combination of globally-supported containment efforts, health experts were able to track the spread of the outbreak, as well as use precautionary and quarantine procedures.

21 Oct 2019

Efficacy News and Research

Vaccine for Lassa fever set to enter clinical testing in humans

Kidney Health Initiative to study patient preferences for novel renal replacement therapy devices

Risk factors for unemployment with multiple sclerosis vary by age, study finds

Researchers discover unexpected role of mTORC2 protein in colorectal cancer

Cooperative research center at LLNL aims to develop vaccines for chlamydia

Novel agent reduces buildup of toxic proteins in Parkinson's and Alzheimer's animal models

UAB researchers awarded grant to study a vaccine for gonorrhea

Discovery reveals why newer PD-1 targeted therapies sometimes fail

Q-Suite Motor Assessment Tool helps detect subtle motor abnormalities in children

Biogen to pursue FDA regulatory approval for investigational drug aducanumab

LSU Health New Orleans awarded $1.74 million to advance research on Usher syndrome

Researchers elucidate properties of blood factor involved in weight loss and aging

Oncolytics Biotech and PrECOG collaborate to study metastatic breast cancer

Creatine powers fight against cancer, improves efficacy of immunotherapies

New findings demonstrate how subtle social interactions can impact clinical outcomes

Ebola virus vaccine still effective against the infection even in low concentrations

Researchers use mouse model to better understand mechanism involved in atrial fibrillation

Patients with diabetes may have worse lung infections

New method may offer effective treatment for pancreatic cancer with fewer side effects

Creatine serves as a molecular battery to power killer T cells' fight against cancer

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News