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Aerosol vaccine provides low-cost, needle-free TB treatment

A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week in the Proceedings of the National Academy of Sciences.

13 Mar 2008

Increased level of magnetic iron oxides found in Alzheimer's disease

A team of scientists, led by Professor Jon Dobson, of Keele University in Staffordshire, UK, have found, for the first time, raised levels of magnetic iron oxides in the part of the brain affected by Alzheimer's Disease (AD).

13 Mar 2008

Aspirin/NSAID interaction in treatment for second stroke

Stroke patients who use ibuprofen for arthritis pain or other conditions while taking aspirin to reduce the risk of a second stroke undermine aspirin's ability to act as an anti-platelet agent, researchers at the University at Buffalo have shown.

13 Mar 2008

Grant expands UB/NYU study of nurses' work decisions

Keeping newly licensed nurses working in the profession is critical to solving the chronic nursing shortage experienced across the U.S., an issue nursing researchers at the University at Buffalo and New York University have been studying since 2005.

13 Mar 2008

Good news for people with glycogen storage disease type Ia

A gene therapy treatment that restores a missing liver enzyme in test animals could provide a cure for a rare metabolic disorder in humans, according to Duke University Medical Center researchers.

13 Mar 2008

Genomics researchers fine-tune marker for common obesity gene

Genomics researchers, seeking to replicate another group's discovery of an important gene associated with obesity, have further refined the signal to a particular variant in DNA that may be more helpful in identifying this gene's role in obesity in various human populations worldwide.

13 Mar 2008

Programme of fertility treatment for developing countries

since the world's first "test-tube" baby was born in July 1978 - the benefits of modern infertility treatments have been largely confined to couples in developed countries.

13 Mar 2008

Caring for a family member with a serious heart ailment may increase your risk of cardiac disease

Researchers examined heart risk factors in family members of cardiac patients and found that those who provided all or most of a patient's care had higher levels of risk factors for heart disease than non-caregivers and those who reported higher caregiver strain after six months were more likely to be depressed than those who provided less or no care.

13 Mar 2008

DNA detectives find genetic markers for lung cancers most likely to recur

Researchers at the Johns Hopkins Kimmel Cancer Center have uncovered clearly recognizable genetic alterations in tumors and tissue removed from patients with early-stage lung cancers that look like good predictors of which of these cancers are more likely to recur.

13 Mar 2008

Weight loss more effective than intensive insulin therapy for type 2 diabetics

Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes, according to a diabetes researcher at UT Southwestern Medical Center.

12 Mar 2008

Personal counseling beats web-based information for weight loss

Individuals are less likely to regain lost weight when they get monthly tips straight from trained counselors rather than from a weight-loss Web site, according to results of a study by Johns Hopkins and other researchers.

12 Mar 2008

Researchers may have found test for depression

Researchers from the University of Illinois at Chicago College of Medicine have discovered that a change in the location of a protein in the brain could serve as a biomarker for depression, allowing a simple, rapid, laboratory test to identify patients with depression and to determine whether a particular antidepressant therapy will provide a successful response.

12 Mar 2008

Maintaining weight loss long term is possible with group sessions

People who shed weight and want to keep it off might benefit from monthly personal contact interventions, researchers reported at the American Heart Association's Conference on Nutrition, Physical Activity and Metabolism.

12 Mar 2008

Short-term stress impairs brain-cell communication

Short-term stress lasting as little as a few hours can impair brain-cell communication in areas associated with learning and memory, University of California, Irvine researchers have found.

12 Mar 2008

Current recommendations for weight gain during pregnancy should be revised, says expert

Current recommendations for weight gain during pregnancy - developed by the Institute of Medicine (IOM) in 1990 - should be revised, according to an internationally recognized obesity expert and chairman of the department of obstetrics, gynecology and women's health at Saint Louis University.

12 Mar 2008

New discovery could change future diagnosis and therapy of depression

12 Mar 2008

A road map to safer pain control, cost savings during colonoscopies

At a time when several U.S. health insurers have discontinued payment for use of the sedative propofol during most screening colonoscopies, physicians at the University of Pennsylvania School of Medicine have discovered that an alternative way to administer the drug could both save millions of health care dollars and provide a safer way to deliver optimal pain relief.

12 Mar 2008

Myostatin shows promise for muscular dystrophy

Myostatin, a protein that blocks muscle growth, has shown promising results as a potential therapeutic target for treating muscular dystrophy in animal studies, where its inhibition led to increased muscle mass and strength.

12 Mar 2008

Glaucoma associated with increased risk of cardiovascular death in black patients

In a population of African origin, persons with diagnosed and treated glaucoma appeared to have an increased risk of death from cardiovascular causes, according to a study by Suh-Yuh Wu, and colleagues in the Departments of Preventive Medicine and Ophthalmology at Stony Brook University, the University of the West Indies, and the Cleveland Clinic Foundation.

12 Mar 2008

Researchers find treatment for familial cold autoinflammatory syndrome

Dalhousie Medical School dermatologist Dr. Barrie Ross and his colleagues have successfully ended a 20-year quest to find a treatment for Familial Cold Autoinflammatory Syndrome (FCAS).

12 Mar 2008