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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Study: Reducing mutated Huntington disease protein restores psychiatric impairments in mice

New research from the University of British Columbia suggests that reducing mutated Huntington disease protein in the brain can restore cognitive and psychiatric impairments in mice.

4 Oct 2018

RCIGM and IDbyDNA launch clinical trial to improve diagnostics for pediatric CNS infections

The Rady Children's Institute for Genomic Medicine and IDbyDNA, a metagenomics technology company translating microbial genomics into actionable information for healthcare providers, have launched a clinical trial to improve diagnostics for pediatric central nervous system infections.

3 Oct 2018

DNA Script successfully synthesizes world's first 150-nucleotide strand of DNA

DNA Script, the global leader in the development of enzymatic DNA synthesis, today announced that it has successfully synthesized the world's first 150-nucleotide strand of DNA by de novo enzymatic synthesis.

3 Oct 2018

Panel of human antibodies developed to neutralize black mamba snake toxin

IONTAS Limited, a leader in the discovery and optimisation of fully human antibodies, today announced a collaborative paper published in Nature Communications with the Technical University of Denmark, and the Instituto Clodomiro Picado of the University of Costa Rica describing the development of a panel of human antibodies that neutralise elements of black mamba snake toxin in an in vivo model.

3 Oct 2018

Researchers insert just enough human DNA into mice to study preterm birth

Preterm birth remains a global epidemic linked to a lifetime of potential health complications. It also is difficult to study in living creatures--especially the uniquely precise biology of preterm birth in humans.

3 Oct 2018

Molecule research reveals potential drug target for treating stroke patients

In an extension of research published a month ago in Nature Methods, a novel hybrid approach performed by researchers from Clemson University's department of physics and astronomy and Stony Brook University has revealed a 3-D structure of a protein fragment that could serve as a drug target in treating stroke patients.

3 Oct 2018

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Fixing or replacing faulty genes has emerged as a key to unlocking cures for numerous devastating diseases. But if the new, engineered genes can't find their way into the patient's genomic sequence, they won't help.

3 Oct 2018

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

Researchers at the Centre for Genomic Regulation in Barcelona, Spain, have identified the mechanism by which an important enzyme involved in the differentiation of stem cells is brought to the DNA.

3 Oct 2018

NIH Director's New Innovator Award for Vanderbilt professor

Reyna Gordon, PhD, assistant professor of Otolaryngology and director of the Music Cognition Lab in the Department of Otolaryngology at Vanderbilt University Medical Center, has received a National Institutes of Health (NIH) Director's New Innovator Award of $2.3 million in total costs for her project, "Biomarkers of Rhythmic Communication: Integrating Foundational and Translational Approaches."

3 Oct 2018

Immune protein 'flutters' like a butterfly in search of viruses, finds study

Researchers at Rutgers Robert Wood Johnson Medical School have identified an important step in the process that allows our bodies to fight viruses.

2 Oct 2018

Genetic variants reveal novel therapeutic targets for chronic kidney disease

The kidney does more than double or even triple duty compared to other organs - it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones.

1 Oct 2018

More people show interest in getting their DNA tested, finds new poll

Only a small percentage of people in their 50s and early 60s have had their DNA tested - either for medical reasons, to learn their ancestry or out of curiosity - but far more have an interest in getting such tests done, according to a new poll.

1 Oct 2018

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited announced today that the phase 3 ECHELON-2 clinical trial met its primary endpoint.

1 Oct 2018

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 1 in the journal Nature Communications.

1 Oct 2018

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Adaptive Biotechnologies today announced that Blood, the Journal of the American Society of Hematology, published online an analysis of patient samples from the Intergroupe Francophone du Myéloma 2009 trial.

1 Oct 2018

Xenex LightStrike Germ-Zapping Robots help reduce infection rates at Martin Medical Center

Patient safety is a top priority at Martin Medical Center, which recently announced that it has seen a significant reduction in its Clostridium difficile (C.diff) infection rates since adopting Xenex LightStrike Germ-Zapping Robots as its environmental standard of care.

1 Oct 2018

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

Angiosarcoma Project, a patient-partnered genomics study, identified immune checkpoint inhibition as a potential treatment option for patients with angiosarcomas of the head, face, neck, or scalp, according to data presented at the fourth CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference.

1 Oct 2018

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Today the U.S. Food and Drug Administration permitted marketing of ClonoSEQ assay, a next generation sequencing-based test for minimal residual disease in patients with acute lymphoblastic leukemiaor multiple myeloma. MRD is a measure of the amount of cancer cells remaining in a person's bone marrow.

30 Sep 2018

Researchers deplete key protein for DNA replication using protein degradation system

Researchers from Tokyo Metropolitan University and the FIRC Institute of Molecular Oncology in Italy have succeeded in depleting AND-1, a key protein for DNA replication, by using a recently developed conditional protein degradation system.

29 Sep 2018

Australian scientists resolve a key question in ovarian cancer care

Australian scientists have revealed a better way to identify which patients should respond to powerful ovarian cancer drugs called PARP inhibitors (PARPi), resolving an important question in ovarian cancer care about why some patients respond to these drugs, while others do not.

28 Sep 2018

DNA News and Research

Further Reading

Study: Reducing mutated Huntington disease protein restores psychiatric impairments in mice

RCIGM and IDbyDNA launch clinical trial to improve diagnostics for pediatric CNS infections

DNA Script successfully synthesizes world's first 150-nucleotide strand of DNA

Panel of human antibodies developed to neutralize black mamba snake toxin

Researchers insert just enough human DNA into mice to study preterm birth

Molecule research reveals potential drug target for treating stroke patients

Hopkins gastroenterologists use endoscopic procedure to deliver therapeutic genes to the liver

Study sheds light on transport of enzyme involved in stem cell differentiation to DNA

NIH Director's New Innovator Award for Vanderbilt professor

Immune protein 'flutters' like a butterfly in search of viruses, finds study

Genetic variants reveal novel therapeutic targets for chronic kidney disease

More people show interest in getting their DNA tested, finds new poll

Phase 3 ECHELON-2 clinical trial evaluating ADCETRIS plus CHP meets primary endpoint

TEAD1 protein appears to be important regulator of tumor migration in glioblastoma

New analysis confirms value of minimal residual disease as prognostic indicator in multiple myeloma

Xenex LightStrike Germ-Zapping Robots help reduce infection rates at Martin Medical Center

New project identifies immune checkpoint inhibition as potential treatment for angiosarcomas

FDA permits marketing of ClonoSEQ assay to detect minimal residual disease in blood cancer patients

Researchers deplete key protein for DNA replication using protein degradation system

Australian scientists resolve a key question in ovarian cancer care

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