Efficacy News and Research

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New polysomnography electrode set enables easy, accurate assessment of sleep bruxism severity

An easy-to-use electrode set can assess sleep bruxism severity as well as a conventional polysomnography, a new study from the University of Eastern Finland shows.

18 Oct 2019

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

A compound effective in killing chemotherapy-resistant glioblastoma-initiating cells has been identified, raising hopes of producing drugs capable of eradicating refractory tumors with low toxicity.

18 Oct 2019

GlobalData highlights low diagnosis and treatment rates of osteoporosis

As World Osteoporosis Day approaches (20 October), it marks a year-long campaign dedicated to raising global awareness of this bone disease. A major unmet need in this space is the low rate of diagnosis and treatment.

18 Oct 2019

Lyme vaccine on the horizon, says new study

Lyme disease is a dreaded disease caused by the bite of an infected tick. The only way to prevent it is by not getting bitten by the tick. However, this is not a practical recommendation, since even today about 300,000 thousand people are diagnosed with this infection, in the US alone, and over 100,000 in Europe, each year.

17 Oct 2019

Researchers to study efficacy of RESHAPE program to reduce stigma of primary care providers

Researchers from the George Washington University, Transcultural Psychosocial Organization Nepal, Tribhuvan University Teaching Hospital, Epidemiology and Disease Control Division of the Ministry of Health and Population of Nepal, Duke University, and King's College London are developing a strategy to reduce mental health stigma among health care providers and subsequently improve detection of patients with mental illness.

17 Oct 2019

Temple researchers win NIH grant to study HIV-related neuroinflammation in context of opioid addiction

The National Institutes of Health has awarded a Temple research team a 5-year, $3.27 million grant to study neuroinflammation following HIV-infection in the context of opioid addiction.

16 Oct 2019

Researchers develop affordable, reliable paper-based sensor to detect iron levels in fortified foods

Many low-income countries have turned to mass food fortification programs to address nutrient deficiencies in their populations. But many of these programs lack the resources needed to determine if the appropriate amount of nutrients is consistently present in those food products.

16 Oct 2019

New discovery paves way for better treatment of diabetes

Insulin, a hormone essential for regulating blood sugar and lipids, is normally produced by pancreatic β cells. In many people with diabetes, however, pancreatic cells are not (or no longer) functional, causing a chronic and potentially fatal insulin deficiency that can only be controlled through daily insulin injections.

16 Oct 2019

DePaul University receives $6.6 million grant to reduce African American youth violence

Psychology researchers at DePaul University have received a $6.6 million grant from the National Institute of Mental Health to reduce African American youth violence.

16 Oct 2019

CDISC and C-Path develop new standard to streamline data for animal rule studies

The Critical Path Institute (C-Path) and CDISC are pleased to announce the release of a global Foundational Standard that describes how to represent data for the natural history and efficacy studies conducted in animals submitted to applications under the U.S. Food and Drug Administration (FDA) regulations commonly known as the Animal Rule.

16 Oct 2019

CRISPR helps find difficult to detect cancer cells

Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in the cancer cells that can make the cells invisible to the immune system normally. Some of the cancers cells can now develop other ways to disguise themselves from being killed by the immune system.

15 Oct 2019

Vitamin D oral sprays equally effective as taking a tablet

Taking vitamin D by oral spray is just as effective as taking a tablet, research from the University of Sheffield has found.

15 Oct 2019

Non-medicine interventions may be more efficacious for treating for psychiatric symptoms of dementia

For patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy may be more effective treatments than medication in some cases, suggests a study publishing Oct. 14 in Annals of Internal Medicine.

14 Oct 2019

Antibody-based eye drops show promise in treating dry eye disease

Dry eye is a condition wherein a person doesn’t have enough tears to lubricate the eye. With the chronic lack of sufficient lubrication, moisture, and nourishment on the eye, it can lead to eye irritation, inflammation, and eventually, scarring.

14 Oct 2019

New therapeutic approach for children born to mothers who used cannabis during pregnancy

As a growing number of U.S. states legalize the medicinal and recreational use of marijuana, an increasing number of American women are using cannabis before becoming pregnant and during early pregnancy often to treat morning sickness, anxiety, and lower back pain.

14 Oct 2019

Diet a significant factor in acne outbreaks, finds pioneering new study

An unhealthy diet, a high level of stress, and extreme skincare routines were the most significant factors related to acne breakouts.

14 Oct 2019

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

In continuing efforts to find novel ways to kill cancer cells, researchers at the University of Maryland School of Medicine have identified a new pathway that leads to the destruction of cancer cells.

14 Oct 2019

Mogrify raises additional $16 million to accelerate the development of life-saving cell therapies

Mogrify Ltd (Mogrify), a UK company aiming to transform the development of life-saving cell therapies, today announced the initial close of its Series A funding. The Company raised $16 million USD in this round, bringing the total investment to over $20 million USD to date.

14 Oct 2019

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Femtogenix Ltd, a UK biotechnology company developing the next generation of DNA-interactive Antibody Drug Conjugate (ADC) payloads, today announced data verifying the favorable toxicity profile and potent efficacy of its Pyridinobenzodiazepine (PDD) ADC payload platform in tumor cell models.

14 Oct 2019

Novel clinical trial to examine use of cannabidiol in people with Parkinson's-related psychosis

A pioneering clinical trial will investigate the use of cannabidiol (CBD) - a compound found in the cannabis plant - in people with Parkinson's-related psychosis.

14 Oct 2019

Efficacy News and Research

New polysomnography electrode set enables easy, accurate assessment of sleep bruxism severity

Researchers identify compound effective in killing chemotherapy-resistant cancer cells

GlobalData highlights low diagnosis and treatment rates of osteoporosis

Lyme vaccine on the horizon, says new study

Researchers to study efficacy of RESHAPE program to reduce stigma of primary care providers

Temple researchers win NIH grant to study HIV-related neuroinflammation in context of opioid addiction

Researchers develop affordable, reliable paper-based sensor to detect iron levels in fortified foods

New discovery paves way for better treatment of diabetes

DePaul University receives $6.6 million grant to reduce African American youth violence

CDISC and C-Path develop new standard to streamline data for animal rule studies

CRISPR helps find difficult to detect cancer cells

Vitamin D oral sprays equally effective as taking a tablet

Non-medicine interventions may be more efficacious for treating for psychiatric symptoms of dementia

Antibody-based eye drops show promise in treating dry eye disease

New therapeutic approach for children born to mothers who used cannabis during pregnancy

Diet a significant factor in acne outbreaks, finds pioneering new study

Combination of two drugs disrupts cancer cells' ability to survive DNA damage, study finds

Mogrify raises additional $16 million to accelerate the development of life-saving cell therapies

Femtogenix announces efficacy, toxicity data of new DNA-binding ADC payload molecules

Novel clinical trial to examine use of cannabidiol in people with Parkinson's-related psychosis

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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