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PRSS3 enzyme linked to aggressive prostate cancer

Researchers at Mayo Clinic's campus in Florida have identified an enzyme specifically linked to aggressive prostate cancer, and have also developed a compound that inhibits the ability of this molecule to promote the metastatic spread of the cancer.

18 Dec 2012

Injecting LECT2 may protect against bacterial sepsis

Failure to launch an adequate immune response may be at the root of septic shock, according to a study published in The Journal of Experimental Medicine on December 17th.

18 Dec 2012

New MIT technology may help make cancer biomarker detection much easier

Finding ways to diagnose cancer earlier could greatly improve the chances of survival for many patients. One way to do this is to look for specific proteins secreted by cancer cells, which circulate in the bloodstream. However, the quantity of these biomarkers is so low that detecting them has proven difficult.

17 Dec 2012

Study successfully identifies ways to manipulate mitoNEET protein

Researchers at UT Southwestern Medical Center have taken another step toward better understanding the metabolic functions of obesity and its connection to type 2 diabetes.

17 Dec 2012

Dantrolene shows promise for treating DMD

A muscle relaxant called dantrolene used for treating malignant hyperthermia boosts the activity of therapies currently being developed to treat the genetic disorder Duchenne muscular dystrophy (DMD), show study findings.

17 Dec 2012

ProMining Therapeutics, Roche to develop small molecule therapeutics for type 2 diabetes mellitus

ProMining Therapeutics, Ltd. today announced a new collaboration with Roche in the field of type 2 diabetes mellitus.

17 Dec 2012

Paternal exposure to cocaine can impair gene expression and behavior in their offspring

Research from the Perelman School of Medicine at the University of Pennsylvania and Massachusetts General Hospital (MGH) reveals that sons of male rats exposed to cocaine are resistant to the rewarding effects of the drug, suggesting that cocaine-induced changes in physiology are passed down from father to son.

17 Dec 2012

New model of how the capsid of viruses assembles

A new model of the how the protein coat (capsid) of viruses assembles, published in BioMed Central's open access journal BMC Biophysics, shows that the construction of intermediate structures prior to final capsid production (hierarchical assembly) can be more efficient than constructing the capsid protein by protein (direct assembly).

17 Dec 2012

Study describes new, paradoxical characteristics of HER2-negative breast cancer

A multicenter study led by researchers at UC Davis describes new, paradoxical characteristics of the most common type of breast cancer. The findings shed light on how the disease can evade treatment and could improve diagnosis and treatment of breast cancer.

15 Dec 2012

Everolimus therapy might treat Myc-driven lymphoma

Drugs that are used in the clinic to treat some forms of breast and kidney cancer and that work by inhibiting the signaling molecule mTORC1 might have utility in treating some of the more than 15 percent of human cancers driven by alterations in the Myc gene, according to data from a preclinical study published in Cancer Discovery, a journal of the American Association for Cancer Research.

15 Dec 2012

Research provides broader understanding of processes that lead to Alzheimer's disease

Alzheimer's disease is the most common form of dementia, affecting over 35 million people worldwide. It is generally assumed that the clumping of beta-amyloid (Aβ) protein causes neuronal loss in patients.

15 Dec 2012

Consuming whole eggs may improve blood lipids, new research suggests

It is estimated that 34% of Americans are affected by an increasingly prevalent condition known as metabolic syndrome which is a combination of at least three of the following risk factors: large waistline, high triglycerides, low HDL cholesterol, high blood pressure and elevated blood sugar.

15 Dec 2012

MDx, Amarantus sign license agreement for LymPro Alzheimer's disease diagnostic blood test

Amarantus BioScience, Inc., a biotechnology company discovering and developing treatments for diseases associated with protein misfolding and apoptosis, today announced that it has licensed the LymPro Alzheimer's Disease Diagnostic Blood Test (LymPro) from Memory Dx, LLC (MDx), formerly known as Provista Life Sciences, Inc.

14 Dec 2012

GSK receives FDA approval for raxibacumab to treat inhalational anthrax

The U.S. Food and Drug Administration today approved raxibacumab injection to treat inhalational anthrax, a form of the infectious disease caused by breathing in the spores of the bacterium Bacillus anthracis. Raxibacumab also is approved to prevent inhalational anthrax when alternative therapies are not available or not appropriate.

14 Dec 2012

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

Every time a human or bacterial cell divides it first must copy its DNA. Specialized proteins unzip the intertwined DNA strands while others follow and build new strands, using the originals as templates. Whenever these proteins encounter a break - and there are many - they stop and retreat, allowing a new cast of molecular players to enter the scene.

14 Dec 2012

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

The plague-causing bacteria Yersinia pestis evades detection and establishes a stronghold without setting off the body's early alarms.

14 Dec 2012

National Cheng Kung University kicks off 23rd International Conference on Genome Informatics

National Cheng Kung University kicked off GIW 2012 -- the 23rd International Conference on Genome Informatics -- at International Conference Hall Dec. 12, attracting more than 140 scholars from 10 countries including Japan, Korea, China, Singapore, Canada, America, Germany, and Australia.

14 Dec 2012

Malaria vaccine trial: an interview with Professor Sir Brian Greenwood

Malaria is an infection caused by a parasite called plasmodium, which is transmitted from person to person by females of some species of mosquito. It is primarily a disease of tropical countries.

14 Dec 2012

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Blocking the receptor for proteins that constrict blood vessels reduces markers of heart-related problems in patients with chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

14 Dec 2012

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

Scientists have identified a new mutation in the gene that causes the inherited disease known as Alpha-1 Antitrypsin Deficiency (Alpha-1), which affects roughly one in 2,500 people of European descent.

14 Dec 2012

G Protein News and Research

PRSS3 enzyme linked to aggressive prostate cancer

Injecting LECT2 may protect against bacterial sepsis

New MIT technology may help make cancer biomarker detection much easier

Study successfully identifies ways to manipulate mitoNEET protein

Dantrolene shows promise for treating DMD

ProMining Therapeutics, Roche to develop small molecule therapeutics for type 2 diabetes mellitus

Paternal exposure to cocaine can impair gene expression and behavior in their offspring

New model of how the capsid of viruses assembles

Study describes new, paradoxical characteristics of HER2-negative breast cancer

Everolimus therapy might treat Myc-driven lymphoma

Research provides broader understanding of processes that lead to Alzheimer's disease

Consuming whole eggs may improve blood lipids, new research suggests

MDx, Amarantus sign license agreement for LymPro Alzheimer's disease diagnostic blood test

GSK receives FDA approval for raxibacumab to treat inhalational anthrax

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

Scientists discover how Yersinia pestis avoids setting off immune system's early infection-alarm

National Cheng Kung University kicks off 23rd International Conference on Genome Informatics

Malaria vaccine trial: an interview with Professor Sir Brian Greenwood

ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD

Scientists identify new mutation in a gene that causes Alpha-1 Antitrypsin Deficiency

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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