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Researchers reanalyze COVID RECOVERY trial data on tocilizumab

A Bayesian analysis of the RECOVERY trial suggests the immunosuppressive drug tocilizumab can reduce deaths in hospitalized COVID-19 patients taking corticosteroids as well as patients on oxygen or non-invasive ventilation and likely increases hospital discharge rates. However, it is not clear if patients on invasive ventilation also benefit.

24 Jun 2021

Green tea catechins might be useful as pan-coronavirus inhibitors

Scientists from the Queen’s University, Canada, have recently uncovered the broad-spectrum antiviral activity of epigallocatechin gallate, a bioactive compound from green tea, against highly pathogenic coronaviruses found in humans and animals. The compound prevents viral infection by interfering with virus-host cell attachment. The study is currently available on the bioRxiv* preprint server.

24 Jun 2021

Bivalent DNA SARS-CoV-2 vaccine induces strong humoral and cellular immunity in mice

A team of UK-based scientists has developed and validated a DNA vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that encodes both spike receptor-binding domain (RBD) and nucleocapsid of the virus as vaccine immunogens.

24 Jun 2021

Researchers identify the best masks for blocking respiratory droplets

During the COVID-19 pandemic, cloth face masks became a way to help protect yourself and others from the virus. And for some people, they became a fashion statement, with many fabric choices available.

24 Jun 2021

Resurgent SARS-CoV-2 infections in England linked to Delta variant

A major factor contributing to the ongoing pandemic of severe acute respiratory coronavirus 2 (SARS-CoV-2) has been the emergence of new variants. Because the mutations of the original virus make variants more transmissible, there is more potential for the contagion to spread through social mixing due to the easing of lockdown.

24 Jun 2021

A study of circulating biomarkers in hospitalized patients infected with SARS-CoV-2 alpha variant

Now, a new study published on the medRxiv* preprint server proposes a rapid method to identify the mutations in B.1.1.7 (N501Y mutation and H69/V70 deletion) and the impact of this variant on various biomarkers in hospitalized patients. This is the first study that correlates the biomarker levels to SARS-CoV-2 variants.

23 Jun 2021

SARS-CoV-2 detection with a simple, inexpensive, and sensitive molecular test

Researchers from the US recently described a rapid molecular test named WHotLAMP for the detection of SARS-CoV-2 in saliva. WHotLAMP is easy to use, very sensitive at 3.6 viral RNA copies per microliter of saliva, specific, and inexpensive. This study is published on the medRxiv*preprint serve.

23 Jun 2021

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

A new analysis of current data indicates that remdesivir does not show efficacy in regulating the severity of the illness.

23 Jun 2021

SARS-CoV-2 Delta variant likely to become dominant in the United States

Researchers have conducted a study showing that the B.1.1.7 lineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that emerged in the UK is now rapidly being displaced as the dominant strain in the United States by the variants of concern B.1.617.2 (Delta) and P.1 (Gamma) that emerged in India and Brazil, respectively.

23 Jun 2021

Research suggests people living with HIV/AIDS may be less susceptible to SARS-CoV-2

Researchers in India have conducted a study showing that the seroprevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – was lower among people living with HIV and AIDS than among the general population.

23 Jun 2021

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

A new study published on the bioRxiv* server describes the changes in the representation of a subset of activated monocytes in this group of patients.

23 Jun 2021

Increased severity of COVID-19 in pregnancy

A new preprint on the medRxiv* server provides more evidence that COVID-19 likely causes a more serious phenotype to arise in pregnant women.

23 Jun 2021

Can antioxidants help manage neurological complications in COVID-19?

In a recent study published in Antioxidants, researchers evaluated the use of antioxidants as potential adjuvants for the treatment of COVID-19.

23 Jun 2021

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

A recent study published in Frontiers in Immunology focuses on the roles of the SADS-CoV N protein in IFN suppression during infection.

23 Jun 2021

Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants

A recent study published in The Innovation evaluated the possibility of community transmission caused by a SARS-CoV-2 variant from an animal.

23 Jun 2021

SARS-CoV-2 infection and transmission in the North American deer mouse

A recent study conducted in Canada reports that the North American deer mouse can be infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from humans.

23 Jun 2021

Repurposing immunomodulatory drugs to treat COVID-19

EULAR has released new points to consider on the use of immunomodulatory drugs in the fight against severe COVID-19.

23 Jun 2021

Repeated vaccination could control infection with SARS-CoV-2 variants among infection-naïve individuals

Researchers have suggested that repeated vaccination against SARS-CoV-2 may enable previously uninfected individuals to cope with viral variants.

23 Jun 2021

Indian SARS-CoV-2 variant has unique infection and immune escape strategy say researchers

Researchers have conducted a study suggesting that the B.1.617 lineage of SARS-CoV-2 that emerged in India has evolved a unique strategy.

23 Jun 2021

Recovering from critical COVID-19: A secondary analysis of a UK study

A study has aimed to characterize the severity levels of fatigue as a long-lasting symptom post-COVID-19 in patients who were ICU-survivors.

23 Jun 2021

Respiratory News and Research

Researchers reanalyze COVID RECOVERY trial data on tocilizumab

Green tea catechins might be useful as pan-coronavirus inhibitors

Bivalent DNA SARS-CoV-2 vaccine induces strong humoral and cellular immunity in mice

Researchers identify the best masks for blocking respiratory droplets

Resurgent SARS-CoV-2 infections in England linked to Delta variant

A study of circulating biomarkers in hospitalized patients infected with SARS-CoV-2 alpha variant

SARS-CoV-2 detection with a simple, inexpensive, and sensitive molecular test

Study finds no evidence for remdesivir's benefit in severe COVID-19 patients

SARS-CoV-2 Delta variant likely to become dominant in the United States

Research suggests people living with HIV/AIDS may be less susceptible to SARS-CoV-2

CD39+ monocyte count higher in pregnant than non-pregnant COVID-19 patients

Increased severity of COVID-19 in pregnancy

Can antioxidants help manage neurological complications in COVID-19?

SARS-CoV N protein elicits production of IFN-β by provoking ubiquitination of RIG-I, finds study

Assessing the extent of community spread caused by mink-derived SARS-CoV-2 variants

SARS-CoV-2 infection and transmission in the North American deer mouse

Repurposing immunomodulatory drugs to treat COVID-19

Repeated vaccination could control infection with SARS-CoV-2 variants among infection-naïve individuals

Indian SARS-CoV-2 variant has unique infection and immune escape strategy say researchers

Recovering from critical COVID-19: A secondary analysis of a UK study

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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