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Research extends powerful capabilities of MRI to nanometer scale

A new technique that brings magnetic resonance imaging to the nanometer scale with unprecedented resolution will open the door for major advances in understanding new materials, virus particles and proteins that cause diseases like Parkinson's and Alzhe

21 Feb 2018

Neuroscientists discover novel mechanism of action behind schizophrenia

An international team of researchers led by a Case Western Reserve University School of Medicine scientist has uncovered a novel mechanism in which a protein--neuregulin 3--controls how key neurotransmitters are released in the brain during schizophrenia.

21 Feb 2018

Reformulating vaccines to prevent relapse

Substance abuse, particularly opioid abuse, is an ongoing issue in the U.S. While treatments such as drug counseling and a handful of medications to combat withdrawal symptoms and cravings exist, the fear and risk of relapsing is real.

21 Feb 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Scientists reveal development of improved medicine to fight addiction

Drug addiction continues to plague vast numbers of people across the world, destroying and ending lives, while attempts to develop more effective pharmaceutical addiction treatments continue.

21 Feb 2018

Research opens up new avenue to minimize risks of transplants

A bone marrow transplant is often the only therapy available to save leukemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.

21 Feb 2018

Prophylactic use of haloperidol does not reduce delirium burden

Prophylactic use of the drug haloperidol does not help to prevent delirium in intensive care patients or improve their chances of survival. Therefore, there is no reason anymore to administer the drug as a preventive measure to reduce the burden of delirium.

21 Feb 2018

Scientists pinpoint fertility hormone that could support early pregnancy

The hormone helps prime cells for implantation, a vital stage in early pregnancy when a fertilized egg attaches to the womb lining, the study suggests.

21 Feb 2018

Biomedical engineers create 3D hydrogel scaffolds to transform cells into muscle

Australian biomedical engineers have successfully produced a 3D material that mimics nature to transform cells into muscle.

21 Feb 2018

Study reveals HCT as effective treatment for NHL patients regardless of age

Results from a retrospective study of 1,629 patients with non-Hodgkin lymphoma showed that survival at 4 years following allogeneic hematopoietic cell transplantation for patients age 65 years and older is comparable to patients age 55 to 64 years.

21 Feb 2018

Patients with terminal cancer may be less competent to make big decisions

Patients with terminal cancer face difficult decisions. What treatment options support their goals? When is it reasonable to discontinue care? A study published in the American Journal of Geriatric Psychiatry shows that these patients may be less competent to make these decisions than their doctors think.

21 Feb 2018

Antibiotic-producing bacterium releases more metabolites than assumed

The bacterium Streptomyces chartreusis is an antibiotic-producing bacterium that releases more metabolites into the surrounding medium than scientists assumed based on the analysis of the genome. Many of the substances are likely released to mediate interactions with its environment.

21 Feb 2018

Penn study sheds new light on immune cell identity

Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors.

21 Feb 2018

Liquefied brain tissue after stroke may harm surviving brain, UA study finds

Scientists have known for years that the brain liquefies after a stroke. If cut off from blood and oxygen for a long enough period, a portion of the brain will die, slowly morphing from a hard, rubbery substance into liquid goop.

21 Feb 2018

Local environment plays crucial role in aggressiveness of breast cancer

Breast cancer is the most commonly diagnosed cancer in women -- one in eight (12.4 percent) in the U.S. will be diagnosed with it. Invasive breast cancer is dangerous for two reasons: It can aggressively spread to other organs in the body, and it is likely to recur.

21 Feb 2018

Wine polyphenols may be good for oral health

Sipping wine is good for your colon and heart, possibly because of the beverage's abundant and structurally diverse polyphenols. Now researchers report in ACS' Journal of Agricultural and Food Chemistry that wine polyphenols might also be good for your oral health.

21 Feb 2018

Pioneering study may pave way for effective painkillers to treat neuropathic pain

A pioneering international study, carried out by the University of Granada, Harvard University, the University of California, Los Angeles, the University of Florida, Laval University and the Jackson Laboratory has conducted an in-depth analysis of the molecular differences between the most common symptoms associated with neuropathic pain.

21 Feb 2018

Researchers discover five new genetic changes that may increase pancreatic cancer risk

In what is believed to be the largest pancreatic cancer genome-wide association study to date, researchers at the Johns Hopkins Kimmel Cancer Center and the National Cancer Institute, and collaborators from over 80 other institutions worldwide discovered changes to five new regions in the human genome that may increase the risk of pancreatic cancer.

21 Feb 2018

Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease.

21 Feb 2018

Advanced method holds promise for substantial improvements in breast cancer diagnosis

Enhancing the diagnosis of breast cancer is the stated goal of a research team at the German Cancer Research Center in Heidelberg. The scientists have combined an advanced method of diffusion-weighted MR imaging with intelligent image analysis methods to detect malignant changes in tissues.

21 Feb 2018