Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Polypharmacy linked to negative health outcomes in older adults with Alzheimer's

Polypharmacy, commonly defined as taking five or more medications daily, is a significant health care concern impacting over 30% of older adults.

1 Nov 2024

Research uncovers new mechanism in protein aggregation linked to Parkinson's disease

A team of researchers at Kumamoto University has uncovered a groundbreaking mechanism in the formation of harmful protein aggregates that lead to neurodegenerative diseases such as Parkinson's Disease.

1 Nov 2024

Glaucoma medication may help prevent Alzheimer's-related tau build-up

A drug commonly used to treat glaucoma has been shown in zebrafish and mice to protect against the build-up in the brain of the protein tau, which causes various forms of dementia and is implicated in Alzheimer's disease.

1 Nov 2024

Innovative approach boosts spatial memory using VR and brain stimulation

EPFL researchers have combined virtual reality, non-invasive brain stimulation and advanced brain imaging techniques to improve spatial navigation in healthy participants. The study is a first step in addressing dementia in an aging population without medication or surgery.

1 Nov 2024

Targeting necroptosis could halt nerve cell loss in Alzheimer's

Alzheimer's disease is characterized by a progressive loss of nerve cells leading to a decline in memory and cognition.

1 Nov 2024

Brain actively engages with immune system to maintain health

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue.

1 Nov 2024

NIH grant funds study to understand how chemical exposure impacts Alzheimer’s risk

To better understand how day-to-day exposures to chemicals earlier in life can contribute to conditions like Alzheimer's disease later on, researchers at the Perelman School of Medicine of the University of Pennsylvania, Northwestern University, University of California San Francisco, and Emory University received an $11 million National Institutes of Health grant

30 Oct 2024

Exercise linked to lower mortality risk in dementia patients

Physical activity of any intensity after a diagnosis of dementia is associated with around a 30% lower risk of death, finds research published online in the British Journal of Sports Medicine.

30 Oct 2024

Positive aging expectations linked to better cognitive perception

Getting older brings certain expectations, from gray hair and wrinkles to more bouts of forgetfulness. While these beliefs may seem harmless, whether a person views these changes in a positive or negative light may influence how they perceive their cognitive abilities, according to a new study from researchers in the Penn State College of Nursing.

29 Oct 2024

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Heather Snyder discusses the Alzheimer's Association's research initiatives, breakthroughs in diagnostics, and the importance of collaboration in dementia care.

28 Oct 2024

Scientists uncover "superspreader" fibrils driving Alzheimer's Disease

The treatment of dementia disorders such as Alzheimer's is still one of the greatest challenges facing modern medicine. In the course of neurodegenerative diseases, certain proteins such as the amyloid β protein accumulate in the brain. They are suspected of being linked to the development of the disease, which is why they are considered a promising target for therapeutic approaches.

28 Oct 2024

Wayne State University researcher secures $2.3 million for Alzheimer's studies

A Wayne State University School of Medicine faculty member has been awarded a total of $2.3 million by the National Institute on Aging of the National institutes of Health for two new, concurrent projects that both address questions related to Alzheimer's disease, a progressive, age-related degenerative brain disease characterized by memory problems, impaired judgment, cognitive issues and changes in personality.

26 Oct 2024

MHRA greenlights donanemab for early stage Alzheimer’s disease

The Medicines and Healthcare products Regulatory Agency (MHRA) has today, 23 October 2024, approved a license for the medicine donanemab (Kisunla) for use in the early stages of Alzheimer’s disease, following a thorough review of the benefits and risks.

26 Oct 2024

Study links gut bacteria infection to Alzheimer's disease progression

A groundbreaking study by researchers at Florida State University's Gut Biome Lab has revealed a potential link between an infection caused by gut bacteria and the progression of Alzheimer's disease.

24 Oct 2024

Research uncovers new insights into neuronal aging and rejuvenation

When a neuron ages, it loses synaptic connections with other neurons, it is less able to transmit nerve impulses, and its metabolism is also altered. This process of neuronal aging — inevitable with the passing of time — is particularly accelerated and becomes a risk factor in neurodegenerative pathologies such as Alzheimer's disease.

24 Oct 2024

Brain aging may hold the key to predicting Alzheimer’s risk

Research reveals advanced brain aging in older adults correlates with cognitive decline and Alzheimer's risk, highlighting the need for early intervention.

24 Oct 2024

Semaglutide may lower Alzheimer's risk in type 2 diabetes patients

Researchers at the Case Western Reserve School of Medicine have found that, when compared to seven other anti-diabetic drugs, semaglutide, a popular diabetes and weight-loss drug, may lower the risk of Alzheimer's disease in people with type 2 diabetes (T2D).

24 Oct 2024