Cancer Treatment News and Research

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New enzyme targets hold promise for cancer therapies

Researchers at Baylor College of Medicine and collaborating institutions have uncovered new potential therapeutic targets for cancer and new insights into existing cancer drug targets, expanding the breadth of possibilities for treating this disease. Using a comprehensive approach that included integrating proteomics, genomics and epigenomics data from 10 cancer types, the team identified protein and small protein or peptide targets in cancer tissues and validated many of them experimentally as promising candidates for therapeutic strategies. The study appeared in Cell.

25 Jun 2024

Expert orthopedic surgeon saves man’s leg from being amputated after damage from advanced cancer

Richard Monti, a father of six and a real estate developer on Long Island, thought that his metastatic kidney cancer diagnosis would be the toughest battle to endure in his life.

21 Jun 2024

New Approach to Treating Melanoma

An international research team, led by Professor Wenbo Bu of Fudan University and Distinguished Professor Dayong Jin of the University of Technology Sydney, have discovered an innovative method to effectively treat cancer by reactivating suppressed metabolic pathways in cancer cells.

20 Jun 2024

Iontronic technology shows promise in slowing malignant brain tumor growth

When low doses of cancer drugs are administered continuously near malignant brain tumors using so-called iontronic technology, cancer cell growth drastically decreases.

19 Jun 2024

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

A genetic treatment targeting the causal NRAS c.181C>A mutation in congenital melanocytic naevus.

19 Jun 2024

Targeting DUSP6 protein to prevent breast cancer recurrence

Treatment outcomes for breast cancer have become better over the years, but proportion of breast cancers still recur even after long periods without signs of cancer remaining dormant in the body.

19 Jun 2024

Study: Anti-inflammatory drug celecoxib benefits PIK3CA-mutated colon cancer patients

An analysis of data from a randomized clinical trial for patients with stage 3 colon cancer found that those with PIK3CA mutations who took celecoxib, an anti-inflammatory drug, after surgery lived significantly longer and had longer disease-free survival compared to those without the mutation.

18 Jun 2024

New hope for GI cancers: Review analyzes molecular targets and treatment advancements

Gastrointestinal (GI) cancers, encompassing esophageal, gastric, small bowel, and colorectal carcinomas, represent a significant global health burden due to their high incidence and mortality rates.

18 Jun 2024

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

In studies with genetically engineered mice, Johns Hopkins Medicine researchers say they have identified a potentially new biological target involving Aplp1, a cell surface protein that drives the spread of Parkinson's disease-causing alpha-synuclein.

18 Jun 2024

Finnish researchers discover mechanism behind breast cancer cell reactivation

Treatment outcomes for breast cancer have become better over the years, but proportion of breast cancers still recur even after long periods without signs of cancer remaining dormant in the body.

17 Jun 2024

Targeting basophils to revitalize cytotoxic T-cells in tumor microenvironment

The ecosystem that surrounds a tumor, also known as the tumor microenvironment, includes immune cells, tissues, blood vessels and other cells that interact with each other and with the tumor.

13 Jun 2024

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Scientists at Weill Cornell Medicine discovered a previously unknown link between two key pathways that regulate the immune system in mammals - a finding that impacts our understanding of chronic inflammatory bowel diseases (IBD).

12 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy - a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers - is low, despite a Food and Drug Administration warning.

12 Jun 2024

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

Engineers at the University of California San Diego have developed microscopic robots, known as microrobots, capable of swimming through the lungs to deliver cancer-fighting medication directly to metastatic tumors.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

UC Davis pioneers advanced PET imaging to monitor lung cancer treatment

Lung cancer can advance quickly. Once a person starts treatment, it is vital to know if that treatment is working or if the patient should be switched to a different treatment.

10 Jun 2024

Discovery could accelerate efforts to produce new antibiotics in the fight against antimicrobial resistance

A discovery made by scientists at King's College London could speed up efforts to produce new antibiotics in the fight against antimicrobial resistance.

10 Jun 2024

Precision-guided treatment boosts outcomes in children with high-risk cancers

Study reveals that precision-guided treatment (PGT) improves outcomes in high-risk pediatric cancer patients, but clinical adoption remains low due to physician uncertainty and lack of long-term survival data.

10 Jun 2024

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

Fibroblast activation protein (FAP)-targeted radioligand therapy is safe and effective for treating patients with progressive metastatic tumors, specifically advanced sarcomas, according to research presented at the 2024 Society of Nuclear Medicine and Molecular Imaging Annual Meeting.

10 Jun 2024

New therapeutic target discovered for treatment-resistant melanoma

An international research team led by scientists from the University of Liège (Belgium) has discovered an interesting new therapeutic target for the treatment of melanoma resistant to targeted therapies.

8 Jun 2024

Cancer Treatment News and Research

New enzyme targets hold promise for cancer therapies

Expert orthopedic surgeon saves man’s leg from being amputated after damage from advanced cancer

New Approach to Treating Melanoma

Iontronic technology shows promise in slowing malignant brain tumor growth

Causal variant-targeted ribonucleic acid treatment for congenital melanocytic nevi

Targeting DUSP6 protein to prevent breast cancer recurrence

Study: Anti-inflammatory drug celecoxib benefits PIK3CA-mutated colon cancer patients

New hope for GI cancers: Review analyzes molecular targets and treatment advancements

Existing cancer drug shows promise in blocking alpha-synuclein spread in Parkinson's mice

Finnish researchers discover mechanism behind breast cancer cell reactivation

Targeting basophils to revitalize cytotoxic T-cells in tumor microenvironment

New research sheds light on IL-23's role in chronic inflammatory bowel diseases

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

UC San Diego engineers develop algae-based microrobots for lung cancer treatment

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

UC Davis pioneers advanced PET imaging to monitor lung cancer treatment

Discovery could accelerate efforts to produce new antibiotics in the fight against antimicrobial resistance

Precision-guided treatment boosts outcomes in children with high-risk cancers

Innovative FAP-targeted radioligand therapy controls disease progression in sarcoma

New therapeutic target discovered for treatment-resistant melanoma

Industry Focus eBook - Cell biology (5th edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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