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UCI neuroscientists discover underlying mechanisms behind brain’s high-level work

Our ability to think, decide, remember recent events and more, comes from our brain's neocortex. Now University of California, Irvine neuroscientists have discovered key aspects of the mechanisms behind these functions.

27 Sep 2022

New research model enables scientists to test therapeutics for rare neurodegenerative diseases

For the first time, scientists will be able to test therapeutics for a group of rare neurodegenerative diseases that affect infants and young children thanks to a new research model created by scientists at the University of Wisconsin–Madison.

26 Sep 2022

Clinical suite to help unlock the mysteries of neurological disorders

A clinical suite at a University of Queensland health research facility is ready to help unlock the mysteries of neurological conditions experienced by one billion people worldwide.

26 Sep 2022

Research reveals the role of microglia-neuron connections during brain development

The Laboratory of Neuroimmunology of the Institute of Experimental Medicine, Budapest, Hungary, led by Ádám Dénes, describes the presence of a direct interaction site between microglial cells and the cell body of developing neurons, and reveals its role during brain development.

20 Sep 2022

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

A new paper discusses the hope held out by recent results on a compound called irisin, a short protein secreted by skeletal muscle that produces some exercise-related effects on the brain.

15 Sep 2022

Study reveals cellular underpinnings of motor memory acquisition and consolidation

When you are first learning how to ride a bicycle or play a musical instrument, your physical movements are uncoordinated at best.

14 Sep 2022

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Up to three quarters of patients receiving cancer chemotherapy suffer from "chemo brain" - a long-term side effect that makes it harder to remember things, maintain attention, and learn new information. When it strikes children, whose brains are still developing, their schoolwork and self-esteem may suffer.

13 Sep 2022

Neuroscientists reveal precise connections between retinal nerve cells and the midbrain structure

For the first time, neuroscientists from Charité – Universitätsmedizin Berlin and the Max Planck Institute for Biological Intelligence (currently in the process of being established) have revealed the precise connections between sensory neurons inside the retina and the superior colliculus, a structure in the midbrain.

12 Sep 2022

Role of the transketolase-like 1 gene in the development of the modern human brain

In a new study, researchers demonstrated how transketolase-like 1 (TKTL1) gene expression influenced neocortical neurogenesis in modern humans.

12 Sep 2022

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

9 Sep 2022

A single genomic change may have given modern humans an advantage over Neanderthals

A single amino acid change in the transketolase-like 1 (TKTL1) protein may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, researchers report.

9 Sep 2022

Study provides some important new clues to age-related memory decline

One of the most upsetting aspects of age-related memory decline is not being able to remember the face that accompanies the name of a person you just talked with hours earlier.

8 Sep 2022

How a key brain network responds to seasonal shifts in day length

A recent paper examined the difference in neuronal communication in the hypothalamic network that regulates physiological function in response to the photoperiod.

8 Sep 2022

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston.

8 Sep 2022

Single-cell Stereo-seq reveals new insights into axolotl brain regeneration

The axolotl Ambystoma mexicanum is a popular pet due to its unique and cute appearance. Unlike other salamanders undergoing metamorphosis, axolotls (pronounced ACK-suh-LAH-tuhl) never outgrow their larval, juvenile stage, a phenomenon called neoteny.

6 Sep 2022

Somatostatin neurons' properties are specialized in different subregions of the cortex, finds study

The brain's cerebral cortex is made up of distinct regions involved in myriad processes, from sensory perception to cognitive functions like memory, attention, and decision-making. University of Pittsburgh neuroscience researchers have found that the properties of one neuron subtype - somatostatin neurons - are specialized in different subregions of the cortex.

6 Sep 2022

The brain and fat communicate directly

Researchers examine the sensory innervation of fat cells within subcutaneous fat deposits.

4 Sep 2022

UTHSC team wins $2.13 million NINDS award to study early neuron development

The National Institute of Neurological Disorders and Stroke has awarded $2.13 million to a University of Tennessee Health Science Center (UTHSC) team studying how neural cells that build a functional brain are generated during embryonic and neonatal life.

2 Sep 2022

Transcriptomic approach reveals shared classes of neuron types in reptilian and mammalian brains

These days, dragons are keeping Game of Thrones fans on their toes. But they are also providing important insights into vertebrate brain evolution, as revealed by the work of Max Planck scientists on the brain of the Australian bearded dragon Pogona vitticeps.

2 Sep 2022

Understanding how microglia change their states to adapt to different areas of the brain

In this interview, News Medical speaks to Jeffrey Stogsdill, Ph.D., about his latest research exploring how microglia change their state to adapt to different areas of the brain.

2 Sep 2022

Neuron News and Research

UCI neuroscientists discover underlying mechanisms behind brain’s high-level work

New research model enables scientists to test therapeutics for rare neurodegenerative diseases

Clinical suite to help unlock the mysteries of neurological disorders

Research reveals the role of microglia-neuron connections during brain development

Exercise hormone irisin blocks Parkinson's-associated α-synuclein aggregation and related neuronal toxicity

Study reveals cellular underpinnings of motor memory acquisition and consolidation

Treating the cerebrospinal fluid to protect the brain from chemotherapy's toxic effects

Neuroscientists reveal precise connections between retinal nerve cells and the midbrain structure

Role of the transketolase-like 1 gene in the development of the modern human brain

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

A single genomic change may have given modern humans an advantage over Neanderthals

Study provides some important new clues to age-related memory decline

How a key brain network responds to seasonal shifts in day length

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

Single-cell Stereo-seq reveals new insights into axolotl brain regeneration

Somatostatin neurons' properties are specialized in different subregions of the cortex, finds study

The brain and fat communicate directly

UTHSC team wins $2.13 million NINDS award to study early neuron development

Transcriptomic approach reveals shared classes of neuron types in reptilian and mammalian brains

Understanding how microglia change their states to adapt to different areas of the brain

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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