immunity News and Research

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Probiotic drink kefir shows promise in preventing Alzheimer’s

Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid buildup, suggesting a role in Alzheimer’s prevention and management. However, more clinical trials are needed to confirm its effectiveness in human patients.

17 Mar 2025

Fighting cancer, inflammation and unlocking dementia diagnostics

In recognition of their discovery of one of our immune system’s foundations, physician Andrea Ablasser, virologist Glen Barber and biochemist Zhijian J. Chen will be awarded the Paul Ehrlich and Ludwig Darmstaedter Prize 2025, endowed with €120,000, in Frankfurt’s Paulskirche today.

14 Mar 2025

Long-COVID symptoms persist for two years in over half of cases

23% of people infected with SARS-CoV-2 between 2021 and 2023 developed long-COVID, and in more than half of them the symptoms persisted for two years.

14 Mar 2025

Older adults may have stronger immunity to bird flu, Penn study finds

Prior exposures to specific types of seasonal influenza viruses promote cross-reactive immunity against the H5N1 avian influenza virus, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

13 Mar 2025

How to manage allergies in children

When a child's sniffles and sneezing won't go away for weeks, the cause might be allergies.

13 Mar 2025

Targeted psychological interventions can enhance long-term resistance to misinformation

A new study has found that targeted psychological interventions can significantly enhance long-term resistance to misinformation.

11 Mar 2025

Measles cases surge in Europe amid vaccine gaps

Data presented in the monthly measles and rubella update by the European Centre for Disease Prevention and Control (ECDC) indicate ongoing transmission of measles across a number of countries in EU/EEA, with a steep rise in cases reported during 2024.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Decoding programmed cell death in breast cancer

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC remains a significant global health challenge.

11 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

Canary in the coalmine: Study warns 21 million children missed measles shots in 2022

Researchers found that 21 million children missed measles vaccination in 2022, far exceeding those missing other vaccines, and 96% were in low- and middle-income countries. The study urges adding measles vaccination rates to global definitions of under-immunized children to better prevent deadly outbreaks.

10 Mar 2025

How falling measles vaccination rates put millions of children at risk

Two-dose measles vaccination coverage has fallen by 3.7% globally since 2019, leaving most WHO regions off track to meet Immunization Agenda 2030 targets. The study highlights a worrying rise in zero-dose children, especially in Africa, threatening global herd immunity against measles.

10 Mar 2025