Immune System News and Research

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Clinical trial examines impact of high-dose omega-3 and vitamin D on halting type 1 diabetes

Scientists from the Diabetes Research Institute at the University of Miami Miller School of Medicine today announced the launch of a new clinical trial that will assess the impact of high-dose omega-3 fatty acids and vitamin D supplementation on halting the progression of type 1 diabetes.

12 Jul 2018

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Ludwig Cancer Research and the Cancer Research Institute announce the initiation of a clinical trial to evaluate the combination of ONCOS-102, an experimental anti-tumor virotherapy, with the checkpoint blockade antibody IMFINZI (durvalumab) for advanced ovarian and colorectal cancers.

12 Jul 2018

Study elucidates pathophysiology of systemic lupus erythematosus

Osaka University researchers elucidated the pathophysiology of systemic lupus erythematosus, an autoimmune disorder that causes inflammation and tissue damage.

11 Jul 2018

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets

11 Jul 2018

Researchers develop biofilm formulations that protect from necrotizing enterocolitis

Most of the time, we think biofilms are bad news. And when pathogenic microbes form biofilms, they are.

11 Jul 2018

Study uncovers process that neutralizes tumor cells

Researchers from the University of California San Diego have identified an unexpected mechanism that could help determine whether a cancer patient will respond to immunotherapy.

11 Jul 2018

Study reveals how M. tuberculosis escapes death in macrophages

The bacteria that cause the devastating disease tuberculosis have the ability to escape destruction and grow after they are engulfed by lung macrophages, the immune cells that are supposed to destroy pathogens.

10 Jul 2018

Study: Mitochondrial DNA in nanovesicles is the alarm that activates antiviral genetic program

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III have provided valuable information about the defense mechanisms of the immune system during the early stages of the response to pathogens such as viruses and bacteria.

10 Jul 2018

New approach could greatly enhance people's long-term tolerance for transplants

Currently, people receiving organ transplants must take drugs to suppress the inflammatory immune response that leads to rejection. Even so, almost all recipients eventually lose their transplant.

10 Jul 2018

Microfluidic chip to detect sepsis proves successful in clinical study

Two years after inventing a microfluidic chip believed to help detect a life-threatening blood infection, researchers in the Texas Tech University Department of Chemistry & Biochemistry and the Texas Tech University Health Sciences Center are finally seeing their product work successfully for human patients.

10 Jul 2018

Mice study shows how vaginal microbiota may affect stress levels of offspring

Exposing newborn mice to vaginal microbes from stressed female mice may transfer the effects of stress to the newborns, according to a new study by researchers at the University of Maryland School of Medicine.

10 Jul 2018

New trial to evaluate whether fasting can improve MS symptoms

People with multiple sclerosis (MS) can find an abundance of conflicting advice suggesting that special diets – everything from avoiding processed foods to going low-carb – will ease their symptoms. But the evidence is scanty that dietary changes can improve fatigue or other MS symptoms.

10 Jul 2018

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

Researchers at the University of Alabama at Birmingham Comprehensive Diabetes Center have discovered a safe and effective novel therapy to reduce insulin requirements and hypoglycemic episodes in adult subjects with recent onset Type 1 diabetes by promoting the patient's own beta cell function and insulin production -- the first such discovery to target diabetes in this manner.

9 Jul 2018

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

CTI BioPharma Corp. and Servier today announced that the pivotal Phase III study evaluating PIXUVRI® combined with rituximab in comparison to gemcitabine combined with rituximab in patients with aggressive B-cell non-Hodgkin lymphoma did not meet its primary endpoint of improvement of progression-free survival

9 Jul 2018

Protein complex that helps shape destiny of developing T cells identified

Like a mentor helping medical students choose between specialties, a protein complex helps shape the destiny of developing T cells, St. Jude Children's Research Hospital scientists have reported.

9 Jul 2018

Step towards an HIV/AIDS vaccine

There has been a four decades long challenge to develop a vaccine against the deadly HIV virus that causes AIDS. Last Saturday the research bore fruit when a team of scientists announced that a trial drug has shown immune response in humans and also protected laboratory monkeys from HIV infection.

9 Jul 2018

UT Southwestern researchers uncover body's microreactors for innate immunity

A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body's first response to infection, UT Southwestern researchers report. The work, reported today in the journal Science, could lead to novel treatments for infections, autoimmune disease, and cancer.

9 Jul 2018

Research suggests new target for malaria vaccine

Researchers have shown that higher levels of Plasmodium falciparum antibodies are protective against severe malaria in children living in Papua New Guinea.

9 Jul 2018

Bacteria adapted to the human body may become more susceptible to antibiotics

A new study published today in Nature Communications, led by scientists at the University of Liverpool in collaboration with the University of Salford, finds evidence that as bacteria adapt to the human body, they can sometimes become more susceptible to antibiotics and therefore easier to kill.

6 Jul 2018

Study: Exposure to greenspace has wide-ranging health benefits

Living close to nature and spending time outside has significant and wide-ranging health benefits - according to new research from the University of East Anglia.

6 Jul 2018

Immune System News and Research

Clinical trial examines impact of high-dose omega-3 and vitamin D on halting type 1 diabetes

New clinical trial to evaluate virotherapy and immunotherapy combination for ovarian, colorectal cancers

Study elucidates pathophysiology of systemic lupus erythematosus

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Researchers develop biofilm formulations that protect from necrotizing enterocolitis

Study uncovers process that neutralizes tumor cells

Study reveals how M. tuberculosis escapes death in macrophages

Study: Mitochondrial DNA in nanovesicles is the alarm that activates antiviral genetic program

New approach could greatly enhance people's long-term tolerance for transplants

Microfluidic chip to detect sepsis proves successful in clinical study

Mice study shows how vaginal microbiota may affect stress levels of offspring

New trial to evaluate whether fasting can improve MS symptoms

Human trial identifies common blood pressure medication as safe, effective therapy for diabetes

CTI BioPharma announces Phase III results of PIXUVRI combined with rituximab in aggressive B-cell NHL patients

Protein complex that helps shape destiny of developing T cells identified

Step towards an HIV/AIDS vaccine

UT Southwestern researchers uncover body's microreactors for innate immunity

Research suggests new target for malaria vaccine

Bacteria adapted to the human body may become more susceptible to antibiotics

Study: Exposure to greenspace has wide-ranging health benefits

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