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Gar genome helps identify genetic sequences shared by human disease genes and zebrafish

Led by Drs John Postlethwait and Ingo Braasch from the Institute of Neuroscience, University of Oregon, US, in collaboration with the Broad Institute, the study of the Spotted Gar (Lepisosteus oculatus) genome reveals that it is small and manageable. Furthermore, it lacks much shuffling and duplication that occurred in the 'main' fish ancestral line; it conserved its genome.

10 Mar 2016

Study: Climbing stairs and years of schooling can promote brain health

Taking the stairs is normally associated with keeping your body strong and healthy. But new research shows that it improves your brain's health too — and that education also has a positive effect.

10 Mar 2016

MDI Biological Laboratory discover mechanisms underlying regeneration of heart tissue

The MDI Biological Laboratory has announced new discoveries about the mechanisms underlying the regeneration of heart tissue by Assistant Professor Voot P. Yin, Ph.D., which raise hope that drugs can be identified to help the body grow muscle cells and remove scar tissue, important steps in the regeneration of heart tissue.

10 Mar 2016

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

A 10-year follow-up study of more than 6,000 people who underwent heart CT scans suggests that a high coronary artery calcium score puts people at greater risk not only for heart and vascular disease but also for cancer, chronic kidney disease and chronic obstructive pulmonary disease (COPD).

10 Mar 2016

Drug-incorporated nanoparticle platforms allow for selective targeting of cancer cells

Cancer is a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. It is a leading cause of death and the burden is expected to grow worldwide due to the growth and aging of the population, mainly in less developed countries, in which about 82% of the world's population resides. By 2030, the global burden is expected to grow to 21.7 million new cancer cases and 13 million cancer deaths simply due to the growth and aging of the population. Current cancer therapy approaches are based in surgery, radiotherapy and chemotherapy, being the chemotherapy the one that shows the greater efficiency for cancer treatment, mainly in more advanced stages. A major problem with this conventional chemotherapy is its toxicity and it also destroys healthy tissues resulting in systemic toxicity besides beneficial characteristics of killing cancer cells. Anticancer drugs also destroy healthy tissues resulting in systemic toxicity.

8 Mar 2016

Research findings may provide highly effective therapeutic strategy for treatment of Alzheimer's, AMD

For the first time, researchers at LSU Health New Orleans have shown that a protein critical to the body's ability to remove waste products from the brain and retina is diminished in age-related macular degeneration, after first making the discovery in an Alzheimer's disease brain. The research team, led by Walter Lukiw, PhD, Professor of Neurology, Neuroscience and Ophthalmology at LSU Health New Orleans Neuroscience Center, also discovered a key reason, identifying a new treatment target.

8 Mar 2016

Healthy aging brings unexpected benefits to pancreatic beta cell function, insulin production

New research shows that a cellular program that causes aging can also bring unexpected benefits in the function of pancreatic beta cells and the production of insulin in mice and humans.

8 Mar 2016

Leading dementia expert calls for greater public awareness of dementia risk factors

A leading dementia expert is calling for greater public awareness of the risk factors for dementia, following a new poll showing only a quarter of British adults think it is possible to reduce their risk of developing the condition.

8 Mar 2016

Social support from family, friends may have a 'mixed blessing' on one's mental health

A recent study conducted by Duke-NUS Medical School researchers suggests that social support from family and friends does not have an entirely positive effect on mental health but is instead a 'mixed blessing'. This is the first study that demonstrates the simultaneous negative and positive effects of social support among Singaporean older adults and has implications for policy makers.

7 Mar 2016

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Scientists from the Cancer Therapy & Research Center in San Antonio today (March 4) published work that provides deeper insight into how the Angelina Jolie gene, BRCA1, functions in normal breast tissue and how its loss results in breast cancer.

7 Mar 2016

Young adults with hostile attitudes may experience memory and thinking problems decades later

Young adults with hostile attitudes or those who don't cope well with stress may be at increased risk for experiencing memory and thinking problems decades later, according to a study published in the March 2, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Mar 2016

Job market study: More PAs enticed towards specialty care than primary care practices

The job market is luring more physician assistants, or PAs, to jobs in specialty care rather than primary care practices such as family medicine and general pediatrics, according to new research from Duke Health.

4 Mar 2016

Preterm neonatal progenitor cells may be a powerful tool for regeneration of damaged kidneys

Cells collected noninvasively from the urine of preterm infants may lead to breakthroughs in regenerative kidney repair for patients with kidney disease and injury, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

4 Mar 2016

Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

Researchers at Schepens Eye Research Institute of Massachusetts Eye and Ear have shown a link between mitochondrial dysfunction in corneal endothelial cells and the development of Fuchs' Endothelial Corneal Dystrophy.

4 Mar 2016

Association for Gerontology in Higher Education announces new awardees

The Association for Gerontology in Higher Education -- the educational branch of The Gerontological Society of America -- is proud to announce its awardees.

3 Mar 2016

Platelet-rich plasma therapy may help improve tissue healing

Tiger Woods, Kobe Bryant and A-Rod have all used it, but does platelet-rich plasma therapy (PRP) really work for the every-day active person? According to a University of Alberta Glen Sather Sports Medicine Clinic pilot study on patients with chronically sore shoulders published in PLOS ONE, preliminary findings say yes.

3 Mar 2016

Labeling dementia as illness affects people’s mood

People who perceive dementia symptoms as an illness feel more negative than those who see it as an inevitable part of getting older, a new study indicates.

3 Mar 2016

Inhibitors that activate brown fat may help treat diabetes, metabolic disorders

In recent decades, obesity has become a global problem. The disease goes hand in hand with a dramatic increase in the proportion of body fat. Researchers from the Max Planck Institute for Metabolism Research and the Cologne Cluster of Excellence in Cellular Stress Responses in Aging-associated Diseases at the University of Cologne have now succeeded in inhibiting a protein in mice that hampers activation of the useful "brown fat" in obese mice. When treated with inhibitors against this protein, obese mice exhibited a notable improvement of their glucose metabolism.

2 Mar 2016

Study provides insights into cellular mechanisms that may contribute to new osteoarthritis treatments

Researchers show that the protein CCN4 positively regulates the generation of cartilage matrix, which are depleted in osteoarthritis.

2 Mar 2016

Report: One in two Americans affected by musculoskeletal condition

An estimated 126.6 million Americans (one in two adults) are affected by a musculoskeletal condition--comparable to the total percentage of Americans living with a chronic lung or heart condition--costing an estimated $213 billion in annual treatment, care and lost wages, according to a new report issued today by the United States Bone and Joint Initiative.

2 Mar 2016

Aging News and Research

Gar genome helps identify genetic sequences shared by human disease genes and zebrafish

Study: Climbing stairs and years of schooling can promote brain health

MDI Biological Laboratory discover mechanisms underlying regeneration of heart tissue

High coronary artery calcium score puts people at greater risk for cancer, kidney disease and COPD

Drug-incorporated nanoparticle platforms allow for selective targeting of cancer cells

Research findings may provide highly effective therapeutic strategy for treatment of Alzheimer's, AMD

Healthy aging brings unexpected benefits to pancreatic beta cell function, insulin production

Leading dementia expert calls for greater public awareness of dementia risk factors

Social support from family, friends may have a 'mixed blessing' on one's mental health

CTRC study provides new insight into how Angelina Jolie gene functions in normal breast tissue

Young adults with hostile attitudes may experience memory and thinking problems decades later

Job market study: More PAs enticed towards specialty care than primary care practices

Preterm neonatal progenitor cells may be a powerful tool for regeneration of damaged kidneys

Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

Association for Gerontology in Higher Education announces new awardees

Platelet-rich plasma therapy may help improve tissue healing

Labeling dementia as illness affects people’s mood

Inhibitors that activate brown fat may help treat diabetes, metabolic disorders

Study provides insights into cellular mechanisms that may contribute to new osteoarthritis treatments

Report: One in two Americans affected by musculoskeletal condition

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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