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One injection of gene therapy spreads through brain in animal study

By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain - after one injection of gene therapy.

9 Oct 2007

Negative aspects of close relationships linked to heart disease risk

Individuals whose close relationships have negative aspects, such as conflict and adverse exchanges, appear to have an increased risk of heart disease than those with more positive close relationships, according to a report in the Oct. 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

9 Oct 2007

Study examines the safety of Tasers

A nationwide study examining the safety of Tasers used by law enforcement agencies suggests the devices are safe, causing a low occurrence of serious injuries.

9 Oct 2007

Eating fewer refined carbohydrates may slow the progression AMD

Eating fewer refined carbohydrates may slow the progression of age-related macular degeneration (AMD), according to a new study from researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University.

9 Oct 2007

Link between woman's hips and daughter's risk of breast cancer

In a study of the maternity records of more than 6,000 women, David J.P. Barker, M.D., Ph.D., and Kent Thornburg, Ph.D., of Oregon Health & Science University discovered a strong correlation between the size and shape of a woman's hips and her daughter's risk of breast cancer.

9 Oct 2007

Mario Capecchi shares Nobel Prize in medicine for knockout mice technology

Mario R. Capecchi, Ph.D., distinguished professor of human genetics and biology at the University of Utah's Eccles Institute of Human Genetics and a Howard Hughes Medical Institute investigator, has won the 2007 Nobel Prize in Physiology or Medicine.

9 Oct 2007

Peer influence can help young adults avoid drug use

High-risk teenagers who participate in peer-led substance abuse prevention programs reduce their drug use by approximately 15 percent versus traditional curricula, suggests a study led by researchers at the University of Southern California (USC).

9 Oct 2007

Sir Martin Evans wins Nobel prize for stem cell research

Medical Research Council funded scientist Sir Martin Evans, has been awarded the Nobel Prize in Physiology or Medicine for 2007 alongside Mario R. Capecchi and Oliver Smithies for their discoveries of "principles for introducing specific gene modifications in mice by the use of embryonic stem cells".

9 Oct 2007

Central nervous system infections after heart transplants

Central nervous system infections develop infrequently following heart transplants but are a significant predictor of death, according to an article posted online today that will appear in the December 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.

9 Oct 2007

Taking antidepressants with painkillers dangerous

Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.

9 Oct 2007

SSRIs may double risk of gastrointestinal bleeding

New research shows that selective serotonin reuptake inhibitors (SSRIs), a group of drugs commonly used to treat depression, may double the risk of gastrointestinal bleeding, according to researchers from Wake Forest University School of Medicine and colleagues.

9 Oct 2007

Wyeth Pharmaceuticals to acquire Haptogen

Wyeth Pharmaceuticals, a division of Wyeth has announced the signing of a definitive agreement under which it has acquired Haptogen Ltd., a Scottish company based in Aberdeen that is focused on the discovery of biopharmaceutical therapies.

8 Oct 2007

Study finds almost one-third of children take vitamins

Almost one-third of U.S. children take some form of dietary supplement, most often multivitamins and multiminerals, according to a study conducted in part by researchers at RTI International and the Office of Dietary Supplements at the National Institutes of Health.

8 Oct 2007

Small papillary thyroid cancers are NOT clinically insignificant

Patients with micropapillary thyroid cancer - small tumors equal to or less than 1 centimeter—and tumors even smaller, less than 1 millimeter (mm - are more common and not without a risk as previously thought, according to a new study presented at the 78th Annual Meeting of the American Thyroid Association (ATA) in New York.

8 Oct 2007

Researchers tackle phantom sounds of tinnitus

For the more than 50 million Americans who experience the phantom sounds of tinnitus -- ringing in the ears that can range from annoying to debilitating -- certain well-trained rats may be their best hope for finding relief.

8 Oct 2007

Genes that increase rheumatoid arthritis risk found

Researchers in the United States and Sweden have identified a genetic region associated with increased risk of rheumatoid arthritis (RA), a chronic and debilitating inflammatory disease of the joints that affects an estimated 2.1 million Americans.

8 Oct 2007

HMMR gene emerges as a key player in breast cancer

Researchers in a multicenter international study have identified a new gene that, if mutated, may increase a woman's risk of breast cancer by more than a third.

8 Oct 2007

Pay-for-performance project to improve cardiovascular care

Thousands of heart patients in the Greater New York region will receive top quality, comprehensive cardiac care in an innovative cardiovascular program in which physicians at a major academic medical center will receive incentive payments based on 60 performance measures for outpatient and inpatient care.

8 Oct 2007

Clinical trial for lab-grown neo-bladder to help spinal cord injury patients

Urologists at Thomas Jefferson University Hospital are studying whether a neo-bladder construct grown from a patient's own cells can improve bladder function for adult spinal cord injury patients.

8 Oct 2007

Fraunhofer pharmaceutical agent speeds drug development

It takes a great deal of time and money to develop a new drug. At Biotechnica in Hanover from October 9 to 11, the Fraunhofer Life Sciences Alliance will demonstrate how a pharmaceutical agent can make its way more quickly from the research laboratory to the pharmacy.

8 Oct 2007