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Structural biology uncovers the molecular basis of b1 vitamin transport and deficiency

Vitamin B1, also known as thiamine, is essential for the survival of our cells. The human body can't produce it, but we can maintain healthy levels of this vitamin by eating foods like salmon, legumes, and brown rice.

16 Oct 2024

NYU Langone researchers address the challenges of heart failure in cancer patients

A new scientific statement issued today by the Heart Failure Society of America highlights a critical connection between heart failure (HF) and cancer, with shared mechanisms contributing to the incidence and progression of both diseases.

16 Oct 2024

Alleo and Ubiquigent enter AI-driven strategic partnership to accelerate DUB-focused drug discovery

Ubiquigent Limited (“Ubiquigent”), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced a strategic partnership with Alleo Labs Corp. (“Alleo”), a pioneer in using artificial intelligence (AI) to develop new therapeutics for neurological diseases.

From Ubiquigent Limited 16 Oct 2024

Historical review reveals French contributions to depression research

In an era where mental health awareness is at the forefront of public discourse, a new historical review is shedding light on the often-overlooked French contributions to our understanding of depression.

16 Oct 2024

Safe storage crucial to prevent child drug poisoning

New data shows that the number of children suffering a seizure after swallowing medications or illegal substances has doubled between 2009 and 2023 in the US. The findings were presented today (Wednesday) at the European Emergency Medicine Congress.

16 Oct 2024

Surface contamination, not air, poses nut allergy threat

There is no evidence for the commonly held belief that nut allergens can be spread through aircraft ventilation systems, say allergy and aviation medicine specialists in an evidence review published in the Archives of Disease in Childhood.

15 Oct 2024

Research explores molecular mechanisms connecting TBI to Alzheimer's

Each year, about 2.5 million people suffer from traumatic brain injuries (TBI), which often increases their risk for developing Alzheimer's disease later in life.

15 Oct 2024

Harnessing the power of miRNA for cancer diagnosis and treatment

This study is led by Dr. Shiwei Duan (Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, Zhejiang, China). His team analyzed literature on miRNA, summarizing the close relationship between these small molecules and cancer. miRNA is a type of non-coding RNA that does not encode proteins, but can target more than 60% of human protein-coding genes.

15 Oct 2024

Bias awareness helps bridge the gap between human and AI healthcare

While people are growing more accustomed to AI-driven personal assistants, customer service chatbots and even financial advisors, when it comes to healthcare, most still want it with a human touch.

15 Oct 2024

Efforts to increase diversity in cancer clinical trials fall short

In the U.S., millions of people experience cancer every year but don't have an equal opportunity to access experimental treatments in clinical trials, or to receive treatments that were shown to be effective in patients like them.

15 Oct 2024

Genetic insights transform treatment for children with developmental disorders

Thousands of children with severe developmental disorders have benefited from more targeted treatments and support with genetic insights from the large-scale Deciphering Developmental Disorders (DDD) study, finds a new study.

15 Oct 2024

Revolutionizing AI training by emulating physician education

When human radiologists examine scans, they peer through the lens of decades of training. Extending from college to medical school to residency, the road that concludes in a physician interpreting, say, an X-ray, includes thousands upon thousands of hours of education, both academic and practical, from studying for licensing exams to spending years as a resident.

15 Oct 2024

Yeast discovery offers new insights into cancer survival

The discovery of a surprising way yeast used to brew beer can survive starvation could open the door to new treatments for cancer.

15 Oct 2024

New study reveals mechanism of inflammation in lupus

Immune cells called monocytes produce a key inflammatory protein called interleukin-1 beta (IL-1β) through an unconventional pathway in patients with systemic lupus erythematosus, commonly referred to as lupus, according to a new study by Weill Cornell Medicine investigators.

15 Oct 2024

New insights into pain mechanisms related to viral infections

An article published in the journal Brain, Behavior, and Immunity reports the findings of a study by researchers based in Brazil, the United States and South Korea who set out to understand how viral infections cause pain and to contribute to the search for novel ways of relieving it.

15 Oct 2024

Air pollution increases emergency department visits

Increases in levels of particulate matter in the air, even within World Health Organization guidelines, correspond with an increase in the number of patients going to the hospital emergency department, according to research presented at the European Emergency Medicine Congress today (Wednesday).

15 Oct 2024

Experimental drug RK-33 shows promise in treating breast cancer bone metastasis

In a new study led by Johns Hopkins Medicine, the drug RK-33 has demonstrated promise in treating breast cancer that has spread to the bone (breast cancer bone metastasis). RK-33 was previously shown to help treat other types of cancer and viral illnesses.

15 Oct 2024

Scripps Research identifies binding site on challenging cancer protein

Hormone-driven cancers, like those of the breast and prostate, often rely on a tricky-to-target protein called Forkhead box protein 1 (FOXA1). FOXA1 mutations can enable these types of cancers to grow and proliferate.

15 Oct 2024

SU2C announces grants to support cutting-edge research in a variety of cancers

Stand Up To Cancer (SU2C) today announced grants to several teams of leading cancer investigators in support of cutting-edge research in a variety of cancers including head and neck, pediatric, pancreatic, breast, rectal and gastro-esophageal cancers, as well as research focused on how the microbiome communicates with the immune system.

15 Oct 2024

New method aims to improve lung transplant access for hard-to-match candidates

Researchers at Cleveland Clinic and Case Western Reserve University (CWRU) have developed a new method that could potentially help provide better access to lung transplant for transplant candidates who are hard to match because of their blood type or height.

15 Oct 2024