Drugs News and Research

RSS

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Researchers at the University of Liverpool have shown how SARS-CoV-2 viral proteases attack the host cell, and how this can be targeted to stop virus replication in cell culture using existing drugs.

21 Sep 2021

Congress cites KHN investigation in probe of national academies

The House Committee on Oversight and Reform is requesting a ream of documents from the prestigious National Academies of Sciences, Engineering and Medicine, spurred by a recent KHN investigation that revealed deep ties between pharmaceutical companies and two members of a committee that took a pharma-friendly stance in a recent report on drug waste.

21 Sep 2021

Careful pipetting reduces the stress on cells in culture

Cell viability, defined as the proportion of live cells in a sample, is a fundamental consideration in all cell culture techniques.

From INTEGRA Biosciences 21 Sep 2021

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

An opinion article aims to provide evidence that SP could be the possible factor for initiating the cytokine storm during severe SARS-CoV-2 infection.

21 Sep 2021

Engineers optimize nuclear magnetic resonance tools through molecular dynamics simulations

Gadolinium-based contrast agents, the gold standard in magnetic resonance imaging(MRI) to determine the health of a patient, can be improved, according to Rice University engineers who are refining models they first used to enhance oil and gas recovery.

21 Sep 2021

Drugs and surgery show promise for reducing long-term effects of obesity-related hypertension

Weight-loss medications and surgical procedures show promise for reducing the long-term effects of high blood pressure (also called hypertension) in people who are overweight or have obesity, according to a new American Heart Association scientific statement published today in the Association's journal Hypertension.

20 Sep 2021

NCTN trials gave 14 million years of additional life to cancer patients, analysis finds

Over the past 40 years, people in the U.S. diagnosed with cancer gained 14 million years of additional life thanks to the results of cancer clinical trials conducted by the National Cancer Institute's publicly funded National Clinical Trials Network, according to an analysis to be reported September 20, 2021, at the annual meeting of the European Society for Medical Oncology.

20 Sep 2021

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

In a recent study, researchers study the molecular aspects of SARS-CoV-2 host cell entry and inhibition of host-specific cellular mechanisms.

20 Sep 2021

Role of extracellular vesicles embedded with engineered ACE2 in the neutralization of the SARS-CoV-2 pseudovirus

Researchers discuss the preparation and characterization of EVs-ACE2, along with the production and characterization of SARS-CoV-2 S-pseudovirus.

20 Sep 2021

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Researchers complete an extensive search on previously published studies to understand the efficacy of convalescent plasma in treating COVID-19.

20 Sep 2021

Two proteins work in tandem to build lifelines to cancer cells, study finds

In human cancer cell and mouse studies, researchers from Johns Hopkins Medicine have found that a set of proteins work in tandem to build supply lines that deliver oxygen and nutrients to tumors, enabling them to survive and grow.

20 Sep 2021

Enclosing radiation-loaded particles for targeted treatment of cancer cells

Being able to deliver drugs directly to diseased cells would improve options for treating diseases. Some radioactive isotopes are already approved to target cancers.

20 Sep 2021

Popular class of diabetes medications may be protective against glaucoma

A popular class of diabetes medications called GLP-1R agonists (Trulicity and Rybelsus) may also protect against glaucoma in diabetic patients, according to a new study led by researchers in the Scheie Eye Institute at the University of Pennsylvania's Perelman School of Medicine.

20 Sep 2021

Study finds rising rates of smoking and vaping among teenagers in Ireland

For the first time in 25 years, rates of smoking among teenage boys in Ireland are increasing, according to a study published in ERJ Open Research.

20 Sep 2021

New discovery reveals how immune 'sentinel' cells are maintained

WEHI researchers have made a surprise discovery about how immune 'sentinel' cells are maintained, which could have implications for drugs in development for treating cancer.

20 Sep 2021

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

There may be good news for the nearly 1 million people battling ulcerative colitis, a type of inflammatory bowel condition with no real cure: Statins, a commonly prescribed cholesterol-lowering drug, seem to be an effective, if unexpected, treatment for the condition, according to a new Stanford Medicine study.

20 Sep 2021

New data shows benefit of drug combination for metastatic castration resistant prostate cancer

New findings by researchers at Yale Cancer Center show the drug combination of nivolumab and rucaparib shows clinical activity for patients with chemotherapy-naïve, metastatic castration resistant prostate cancer (mCRPC).

18 Sep 2021

Higher white matter extracellular free-water related to cognitive dysfunction in lupus patients

Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune system attacks the body's own tissues, causing widespread inflammation and damage in the affected organs.

18 Sep 2021

Novel drug combinations improve progression-free survival for patients with advanced NSCLC

New findings from a large study led by researchers at Yale Cancer Center shows the addition of the drugs oleclumab or monalizumab to durvalumab improved progression-free survival for patients with locally advanced non-small cell lung cancer (NSCLC).

18 Sep 2021

'Spice' users likely to experience more severe withdrawal symptoms, study finds

Research published today by psychologists at the University of Bath suggests that 'Spice' – which contains synthetic drugs originally designed to mimic the effects of cannabis – is more harmful than cannabis and that users are likely to experience more severe withdrawal symptoms when attempting to quit.

18 Sep 2021

Drugs News and Research

Study shows how SARS-CoV-2 viral proteases can be targeted to stop virus replication

Congress cites KHN investigation in probe of national academies

Careful pipetting reduces the stress on cells in culture

Neurokinin-1 receptor: a potential drug target for the treatment of COVID-19

Engineers optimize nuclear magnetic resonance tools through molecular dynamics simulations

Drugs and surgery show promise for reducing long-term effects of obesity-related hypertension

NCTN trials gave 14 million years of additional life to cancer patients, analysis finds

SARS-CoV-2 NSP1 protein suppresses host genes while enhancing viral RNA expression

Role of extracellular vesicles embedded with engineered ACE2 in the neutralization of the SARS-CoV-2 pseudovirus

Failures and findings from randomized clinical trials in COVID-19 convalescent plasma

Two proteins work in tandem to build lifelines to cancer cells, study finds

Enclosing radiation-loaded particles for targeted treatment of cancer cells

Popular class of diabetes medications may be protective against glaucoma

Study finds rising rates of smoking and vaping among teenagers in Ireland

New discovery reveals how immune 'sentinel' cells are maintained

Commonly prescribed cholesterol-lowering drugs could be effective in treating ulcerative colitis

New data shows benefit of drug combination for metastatic castration resistant prostate cancer

Higher white matter extracellular free-water related to cognitive dysfunction in lupus patients

Novel drug combinations improve progression-free survival for patients with advanced NSCLC

'Spice' users likely to experience more severe withdrawal symptoms, study finds

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News