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Smokers have lower odds of surviving a heart attack than non-smokers

Smokers have a lower chance of surviving a heart attack than non-smokers, according to new data compiled by researchers at Jordan University of Science and Technology in Irbid.

2 Apr 2022

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

In a paper in the journal Nature, Los Alamos National Laboratory scientists Bette Korber, Hyejin Yoon, Will Fischer and James Theiler, among nearly 130 authors from institutions around the world, describe their groundbreaking collaborative work, "Defining the risk of SARS-CoV-2 variants on immune protection."

1 Apr 2022

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Researchers developed a novel high-throughput method to obtain monoclonal antibodies from COVID-19 individuals infected with SARS-CoV-2 ancestral strain Wuhan-Hu-1 and the Beta or Gamma variants.

1 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

A team of international scientists has recently isolated and characterized pan-coronavirus neutralizing antibodies from individuals with pre-existing immunity against SARS-CoV-2.

1 Apr 2022

The effects of prolonged sleep restriction on energy intake, energy expenditure, and regional fat storage in healthy individuals

A new study provides insights into how experimentally-induced sleeplessness affects body fat when the subject is provided access to food.

1 Apr 2022

No evidence of SARS-CoV-2 in the U.K.'s wild deer population

A new study accepted for publication in the journal Transboundary and Emerging Diseases assesses the potential exposure of U.K. deer to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since studies have shown the spill-over of SARS-CoV-2 infections to the Northern American white-tailed deer. If there is a spill-over, wild deer species can act as reservoirs of SARS-CoV-2 with the possibility of the emergence of new variants.

31 Mar 2022

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Faculty from the Departments of Microbiology, Medicine Genetics and Genomic Sciences, and Pathology and Molecular Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai play key roles in a National Institutes of Health (NIH) program set up to provide a real-time risk assessment of variants of SARS-CoV-2, the virus that causes COVID-19. The program, called SARS-CoV-2 Assessment of Viral Evolution (SAVE) and described in a paper published March 31 in Nature, assesses how the variants might affect transmission, virulence, and resistance to both disease-induced (convalescent) and vaccine-induced immunity.

31 Mar 2022

Therapeutic antibodies against filoviruses including Ebola and Marburg

Researchers discuss the development and structural characterization of therapeutic monoclonal antibodies targeting the surface glycoprotein of filoviruses.

31 Mar 2022

The mucosal antibody response to SARS-CoV-2

Researchers determine mucosal SARS-CoV-2-specific antibody levels and their neutralizing effect in pediatric and adult patients.

31 Mar 2022

The evolution of the SARS-CoV-2 spike protein

Researchers discuss the evolution and mechanisms of mutations that have occurred in the spike protein of SARS-CoV-2.

31 Mar 2022

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

UW Medicine genome scientists were among the leading contributors to the publication of the first complete, gapless sequence of a human genome announced this week by the National Human Genome Research Institute.

31 Mar 2022

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

Most of us remember enough biology to recall that mitochondria are known as "the powerhouse of the cell." Even that audacious term may downplay the importance of mitochondria and what happens when mitochondria go bad.

31 Mar 2022

New project launched to explore how GI microbiota may contribute to neurodegeneration

Alzheimer's disease (AD) is a type of dementia that affects memory, thinking and behavior. According to the Alzheimer's Association, an estimated 6.2 million Americans are living with this progressive neurologic disorder, and it is the sixth-leading cause of death in the U.S.

31 Mar 2022

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

Researchers designed nanoparticles representing RBDs of the S protein of animal sarbecoviruses and SARS-CoV-2 to evaluate their potential as a pan-sarbecovirus vaccine candidate.

31 Mar 2022

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

An exciting study recently published in the PNAS underscores the role of a well-established cytokine IL-13 in protecting our cells against SARS-CoV-2.

31 Mar 2022

Study sheds light on the conformational dynamics of SARS-CoV-1 and SARS-CoV-2 spike proteins

New computational simulations of the behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins prior to fusion with human cell receptors show that SARS-CoV-2, the virus that causes COVID-19, is more stable and slower changing than the earlier version that caused the SARS epidemic in 2003.

31 Mar 2022

Common coronavirus infections don't generate antibodies that effectively cross-react with SARS-CoV-2

Although SARS-CoV-2 has taken the world by storm, it's not the only coronavirus that can infect humans.

30 Mar 2022

Protein C News and Research

Smokers have lower odds of surviving a heart attack than non-smokers

Groundbreaking collaborative work defines the risk of SARS-CoV-2 variants on immune protection

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

The effects of prolonged sleep restriction on energy intake, energy expenditure, and regional fat storage in healthy individuals

No evidence of SARS-CoV-2 in the U.K.'s wild deer population

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Therapeutic antibodies against filoviruses including Ebola and Marburg

The mucosal antibody response to SARS-CoV-2

The evolution of the SARS-CoV-2 spike protein

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

Virginia Tech researcher awarded $1.9 million grant to study about mitophagy

New project launched to explore how GI microbiota may contribute to neurodegeneration

Mosaic-8 RBD-nanoparticles show promise as a vaccine candidate for SARS-CoV-2 and potential sarbecoviruses spillovers

MERS-CoV-related viruses invade host cells via bat angiotensin-converting enzyme 2 receptors

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Study sheds light on biomechanistic reasons why allergic asthma correlates with milder forms of COVID-19

Study sheds light on the conformational dynamics of SARS-CoV-1 and SARS-CoV-2 spike proteins

Common coronavirus infections don't generate antibodies that effectively cross-react with SARS-CoV-2

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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