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Long-term injectables plus counseling improve medication adherence in bipolar disorder patients

Researchers have found that adherence to taking medications improved in people with bipolar disorder with the use of long-term injectable meds combined with psychosocial intervention.

17 Sep 2021

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the disease.

17 Sep 2021

Discovery of biological response platform could provide opportunity to alleviate allergic inflammation

New discoveries about a built-in rapid reaction system that triggers inflammatory responses when people are exposed to allergens, such as insects, mites, and fungi, also may hold the keys to helping more people manage their allergies in years to come.

17 Sep 2021

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

16 Sep 2021

Study highlights the importance of deeply exploring the immune responses against cancer

Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body's own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.

16 Sep 2021

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Heart abnormalities are common complications of sickle cell anemia (SCA) that can contribute to severe disease symptoms and even death.

16 Sep 2021

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

A new study describes a small molecule referred to as RG10 that may have potent antiviral activity against SARS-CoV-2 in human cells.

16 Sep 2021

Multi-million government fund given to 21 projects to propel innovation across the UK

Regulators are clearing the runway for drones to transport vaccines and other live-saving drugs, in a ground-breaking venture funded by government.

16 Sep 2021

Experts raise questions about routine use of surrogate endpoints for drug approvals

A growing number of drugs are being approved on the basis of indirect ('surrogate') measures that do not always reliably predict outcomes that matter most to patients, such as living longer or feeling better.

16 Sep 2021

Research paves the way for advances in the treatment of many brain disorders

Bristol-led research has identified specific drug targets within the neural circuits that encode memories, paving the way for significant advances in the treatment of a broad spectrum of brain disorders.

16 Sep 2021

How Fauci and the NIH got ahead of the FDA and CDC in backing boosters

In January — long before the first jabs of covid-19 vaccine were even available to most Americans — scientists working under Dr. Anthony Fauci at the National Institute of Allergy and Infectious Diseases were already thinking about potential booster shots.

16 Sep 2021

Study looks at drug resistance in BRAF-mutated gliomas

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country - including several from the University of Colorado School of Medicine - to study samples of brain tumors before and after being treated with the drug.

16 Sep 2021

Study identifies probable cause of Alzheimer’s disease

Ground-breaking new Curtin University-led research has discovered a likely cause of Alzheimer's disease, in a significant finding that offers potential new prevention and treatment opportunities for Australia's second-leading cause of death.

16 Sep 2021

BAK/MCL1 complex in tumor cells can predict the sensitivity of chemotherapy drugs in ovarian cancer

A research team led by Prof. DAI Haiming from the Hefei Institutes of Physical Science (HFIPS) of the Chinese Academy of Sciences (CAS) recently announced the constitutive BAK/MCL1 complexes could predict chemotherapy drugs sensitivity of ovarian cancer. The result has been published on Cell death & disease.

16 Sep 2021

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Researchers from the Case Comprehensive Cancer Center uncovered the potentially important role of the protein-coding gene, MYO10, in tumor development and immune therapy response. Their findings were published today in Science Advances.

16 Sep 2021

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Researchers from The University of Texas MD Anderson Cancer Center have discovered that grouping epidermal growth factor receptor (EGFR) mutations by structure and function provide an accurate framework to match patients with non-small cell lung cancer (NSCLC) to the right drugs.

16 Sep 2021

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Autism affects about 2% of children in the United States, and about 30% of these children have seizures. Recent large-scale genetic studies revealed that genetic variants in a sodium channel, called voltage-gated sodium channel Nav1.2, is a leading cause of autism.

15 Sep 2021

Drugs News and Research

Long-term injectables plus counseling improve medication adherence in bipolar disorder patients

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

Discovery of biological response platform could provide opportunity to alleviate allergic inflammation

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Study highlights the importance of deeply exploring the immune responses against cancer

Hydroxyurea therapy can improve or reverse cardiac complications in sickle cell anemia patients

Antiviral compound RG10 acts via intracellular SARS-CoV-2-ER dynamics

Multi-million government fund given to 21 projects to propel innovation across the UK

Experts raise questions about routine use of surrogate endpoints for drug approvals

Research paves the way for advances in the treatment of many brain disorders

How Fauci and the NIH got ahead of the FDA and CDC in backing boosters

Study looks at drug resistance in BRAF-mutated gliomas

Study identifies probable cause of Alzheimer’s disease

BAK/MCL1 complex in tumor cells can predict the sensitivity of chemotherapy drugs in ovarian cancer

Research reveals vital role of protein-coding gene in tumor development and immune therapy response

Grouping EGFR mutations provides an accurate way to match lung cancer patients to the right drugs

Study pinpoints a potential pathway for treating epileptic seizures in patients with autism

Phase I trial investigates using antiparasitic nitazoxanide for treatment of COVID-19

Aptamers for Targeting SARS-CoV-2 Proteins

A sweet pill to swallow: oral nucleoside analog of Remdesivir improved SARS-CoV-2 pathogenesis in mice

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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