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New method to estimate sickle cell disease severity

Researchers from Boston University School of Medicine (BUSM) and Boston University School of Public Health (BUSPH) have developed a method to estimate sickle cell disease severity and predict the risk of death in people with this disease.

12 Jul 2007

Impact of work-hour regulations on medical residents

Four years ago this month, new rules went into effect that restricted the long hours worked by many physicians in training.

12 Jul 2007

Dietary glycemic index linked to risk of vision loss

Age-related macular degeneration (AMD) and its associated vision loss may be connected to the quality of carbohydrates an individual consumes.

12 Jul 2007

Striking north-south differences in EpiPen prescribing

A new study suggests strong variation in the occurrence of anaphylaxis between the northern and southern U.S. Anaphylaxis is a severe allergic reaction that can be fatal without treatment with epinephrine.

12 Jul 2007

Next generation painkillers

Scientists studying one of nature's simplest organisms have helped to unravel the structure of a key molecule that controls pain in humans.

From The University of Manchester 12 Jul 2007

Global Med Technologies awarded new patent for transfusion software

Global Med Technologies has announced that the United States Patent and Trademark Office will be issuing a patent for SafeTrace Tx, its proprietary transfusion software, which is located at more than 337 sites in the United States and abroad.

12 Jul 2007

First mouse model of lung transplantation

Lung transplants have been performed successfully for more than 20 years in humans but never before in mice – until now.

12 Jul 2007

A genetically informed study of the intergenerational transmission of marital instability

The first study to examine genetics as a culprit in the higher-than-usual divorce rate among children of divorced parents found that the parents' divorce itself, not genes or even problems such as parental substance abuse or delinquency, played a key role in the failed unions.

12 Jul 2007

Chemotherapy may benefit all women with a BRCA1 mutation

Breast cancer patients who possess one of the so-called "breast cancer" or BRCA genetic mutations do not have a higher risk of dying than patients with no BRCA mutations, according to a detailed study by researchers at the Technion-Israel Institute of Technology and the University of Toronto.

12 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

40% of community pharmacists don't tell parents they are dispensing off-label drugs to children

Forty per cent of community pharmacists have dispensed an off-label drug to a child in the last month, according to research published in the July issue of the British Journal of Clinical Pharmacology.

12 Jul 2007

New use for a cell toxin found to inhibit survival proteins in cancer cells

A chemically-modified version of a mitochondrial toxin long used to control species of invasive fish in lakes has been found to selectively inhibit two "survival proteins" in cancer cells.

11 Jul 2007

Cancer-causing enzyme could be stopped

Scientists from the MRC's Laboratory of Molecular Biology (LMB) and the Albert Einstein College of Medicine have discovered a way to stop an enzyme responsible for many cancers.

11 Jul 2007

Diabetes researcher honored with prestigious Novartis prize

John E. Gerich, M.D., professor of Medicine and program director of the General Clinical Research Center at the University of Rochester Medical Center, has been awarded the Novartis Prize for Long-Standing Achievement in Diabetes.

11 Jul 2007

Screening for behavioral health first step to getting treatment

Health plans seldom require screening for substance abuse and mental health in primary care even though it can improve detection, according to a new Brandeis University study published in the July issue of the Journal of General Internal Medicine.

11 Jul 2007

Researchers measure effect of hepatitis B on patients' quality of life

"Am I going to die? I have no future." "I feel depressed at times, fearful I may not see my children marry or be a grandparent." Such heart-rending statements from patients with chronic hepatitis B reveal the social and mental impact of this disease, which affects 350 million worldwide.

11 Jul 2007

Detecting cognitive impairment in primary care: Performance assessment of three screening instruments

A new study published in the June issue of Journal of Alzheimer's Disease demonstrates the accuracy and validity of a new mathematics-based memory assessment developed by Medical Care Corporation to detect early signs of memory impairment due to Alzheimer's disease and other related disorders.

11 Jul 2007

Potential role of milk thistle as an anticancer agent

Milk thistle extract, an herbal remedy since the times of the ancient Greeks and Romans, is today one of the most popular herbal supplements, with U.S. retail sales of nearly nine million dollars.

11 Jul 2007

Myomo receives FDA approval to market e100 NeuroRobotic System

Myomo, Inc. has announced that the company received U.S. Food and Drug Administration (FDA) 510(k) clearance to market the Myomo e100 NeuroRobotic System. Myomo's first product is a wearable, portable therapeutic modality designed to allow patients to self initiate and control movement of partially paralyzed limbs using their own biological signals.

11 Jul 2007

Cicardian system suffers and protects from prenatal cocaine exposure

Researchers from Boston University School of Medicine (BUSM) have shown that prenatal cocaine exposure in zebrafish (which share the majority of the same genes with humans) can alter neuronal development and acutely dysregulate the expression of circadian genes and those affecting melatonin signaling, growth and neurotransmission.

11 Jul 2007