Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Lean mass may decline among Alzheimer's patients

Lean mass—the weight of an individual's bones, muscles and organs without body fat—appears to decline among patients with Alzheimer's disease, according to a report in the April issue of Archives of Neurology, one of the JAMA/Archives journals.

13 Apr 2010

Liver biopsy with hepatic copper quantification every 3 years needs to be considered for WD patients

As a result of the rarity of Wilson disease (WD) and the fact that liver biopsy is not performed routinely during follow-up, unless clinically indicated, the progression and timing of the liver pathology and its correlation with different anti-copper treatments or aminotransferase levels are poorly characterized. Previous studies have demonstrated the possibility of improvement of steatosis and inflammation grade, and of fibrosis stage during long-term follow-up.

12 Apr 2010

Hormones leptin and insulin work together to affect regulation of blood sugar levels, female fertility

New findings by UT Southwestern Medical Center researchers suggest that the hormones leptin and insulin work together in specific neurons in the hypothalamus region of the brain to affect both the regulation of blood sugar levels in the body and, surprisingly, female fertility.

12 Apr 2010

Research shows association between LRP16 expression in colorectal cancer and disease related death

Leukemia related protein 16 gene is an important estrogen-responsive gene. LRP16 gene plays an important role in the carcinogenesis and progression of hormone-dependent cancer. LRP16 expression was also reported to be associated with invasion, metastasis and prognosis of gastric carcinoma. But no comprehensive description of LRP16 protein expression in colorectal cancer has been reported.

12 Apr 2010

OptiMedica releases new details on femtosecond laser system for cataract surgery

OptiMedica Corp., a global ophthalmic device company, has released new details regarding the development of its proprietary femtosecond laser system for cataract surgery. The new system, which combines OptiMedica's breakthrough pattern scanning technology, an ultra-fast laser and integrated Optical Coherence Tomography imaging, is designed to dramatically improve the complex cataract procedure by replacing its most technically demanding and manual steps.

12 Apr 2010

Broken heart disease affects women in post menopause period

It seems an infarction, but it's not. It's called Tako-Tsubo syndrome, or stress-induced cardiomyopathy, and it's a rare disease which at first used to be confused with the far more common (and dangerous) cardiac infarction. Patients arrive to the emergency room with the characteristic heart attack symptoms: acute pain in the chest, an electrocardiogram with the typical changes and the release of those enzymes associated with the usual heart disease.

9 Apr 2010

World's largest autism science and advocacy organization awards 16 new research grants

Autism Speaks, the world's largest autism science and advocacy organization, today announced the awarding of 16 new research grants totaling $5,223,743 over the next three years.

9 Apr 2010

Role of beta defensins in development of chronic inflammatory response in the brain

Researchers at the Case Western Reserve University School of Dental Medicine and School of Medicine will look for evidence within the brain for human beta defensin peptide function-proteins important to the peripheral body's natural defense system against infection from the outside environment.

8 Apr 2010

Single vaccine for anthrax and plague: iBio confirms grant of rights

iBio, Inc. confirmed today the grant of rights to use iBio's proprietary technology, the iBioLaunch™ platform, in support of a $5.3 million government-funded project for the development of a single vaccine to protect against both anthrax and plague. The project will be managed by Fraunhofer USA Center for Molecular Biotechnology (CMB) pursuant to the long-term agreement between iBio and CMB for advancement of the iBio technology.

8 Apr 2010

Angiotech Pharmaceuticals acquires manufacturing, intellectual property rights from Haemacure

Angiotech Pharmaceuticals, Inc., a specialty pharmaceutical and medical device company, today announced the closing of its acquisition of certain product candidates and technology assets of Haemacure Corporation. Haemacure has been involved in proceedings under Canada's Bankruptcy and Insolvency Act and Chapter 11 of the United States Bankruptcy Code.

8 Apr 2010

Researchers find new genomic approach to identify smokers at risk of lung cancer

Researchers from Boston University School of Medicine in collaboration with investigators at the University of Utah, have discovered a new approach for identifying smokers at the highest risk for developing lung cancer. The findings, which appear in the April 7th issue of Science Translational Medicine, will allow the researchers to use a genomic approach to prevent lung cancer in these individuals and to personalize cancer chemoprophylaxis and therapy.

8 Apr 2010

Haemacure announces closing of purchase by Angiotech Pharmaceuticals

Haemacure Corporation announces the closing of the purchase by Angiotech Pharmaceuticals, Inc. of substantially all its assets, consisting mainly of its two product candidates and the associated intellectual property and manufacturing plant.

8 Apr 2010

EndoChoice announces acquisition of Pathworks Anatomic Pathology Laboratory

EndoChoice, Inc. announced today that it has acquired Pathworks Anatomic Pathology Laboratory. Founded in 1989, Pathworks is a College of American Pathologists (CAP) accredited national reference laboratory located in Atlanta, GA. Robert Smith, MD, founder of the laboratory, will assume the Medical Director position of EndoChoice Pathology, a wholly-owned subsidiary of EndoChoice, Inc.

8 Apr 2010

Study demonstrates potential ability of Chronix serum DNA assays in diagnosis of breast cancer

Chronix Biomedical today announced publication of a study that supports the utility of its serum DNA blood tests to predict clinical status and monitor disease activity and response to treatment in multiple sclerosis (MS). Chronix Biomedical uses proprietary technology to identify disease-specific genetic fingerprints based on the circulating DNA that is released into the bloodstream by damaged and dying cells.

7 Apr 2010

Research highlights first steps in the formation of Lewy bodies, the hallmark of Parkinson's brain

Although the cause of Parkinson's disease remains a mystery, scientists now have a better understanding of the earliest stages of abnormal aggregation of a key disease-associated protein. The research, published by Cell Press online on April 6th in Biophysical Journal, provides new insight into the first steps in the formation of neurotoxic structures called Lewy bodies that are the hallmark of the Parkinson's brain.

7 Apr 2010

IZI Medical Products introduces Mammography Indicator Markers

IZI Medical Products today announced that the company has developed and begun distributing two new lines of flat mammography markers, which are being manufactured in the United States and sold worldwide under the brand, Mammography Indicator® Markers.

7 Apr 2010

Frequency of complex fusion procedures for lower back increased among Medicare recipients

The frequency of complex fusion procedures to treat spinal stenosis of the lower back increased between 2002-2007 among Medicare recipients, while the rates of decompression and simple fusion procedures decreased, according to a study in the April 7 issue of JAMA.

7 Apr 2010

New study shows utility of Chronix Biomedical's serum DNA tests in MS

Chronix Biomedical today announced publication of a study that supports the utility of its serum DNA blood tests to predict clinical status and monitor disease activity and response to treatment in multiple sclerosis. Chronix Biomedical uses proprietary technology to identify disease-specific genetic fingerprints based on the circulating DNA that is released into the bloodstream by damaged and dying cells.

6 Apr 2010

Src can be most promising targets for cancer therapy

Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.

6 Apr 2010

Rice University's nano-bio-chip 93% specific in detecting patients with premalignant lesions

The gentle touch of a lesion on the tongue or cheek with a brush can help detect oral cancer with success rates comparable to more invasive techniques, according to preliminary studies by researchers at Rice University, the University of Texas Health Science Centers at Houston and San Antonio and the University of Texas M.D. Anderson Cancer Center.

6 Apr 2010

Pathology News and Research

Further Reading

Lean mass may decline among Alzheimer's patients

Liver biopsy with hepatic copper quantification every 3 years needs to be considered for WD patients

Hormones leptin and insulin work together to affect regulation of blood sugar levels, female fertility

Research shows association between LRP16 expression in colorectal cancer and disease related death

OptiMedica releases new details on femtosecond laser system for cataract surgery

Broken heart disease affects women in post menopause period

World's largest autism science and advocacy organization awards 16 new research grants

Role of beta defensins in development of chronic inflammatory response in the brain

Single vaccine for anthrax and plague: iBio confirms grant of rights

Angiotech Pharmaceuticals acquires manufacturing, intellectual property rights from Haemacure

Researchers find new genomic approach to identify smokers at risk of lung cancer

Haemacure announces closing of purchase by Angiotech Pharmaceuticals

EndoChoice announces acquisition of Pathworks Anatomic Pathology Laboratory

Study demonstrates potential ability of Chronix serum DNA assays in diagnosis of breast cancer

Research highlights first steps in the formation of Lewy bodies, the hallmark of Parkinson's brain

IZI Medical Products introduces Mammography Indicator Markers

Frequency of complex fusion procedures for lower back increased among Medicare recipients

New study shows utility of Chronix Biomedical's serum DNA tests in MS

Src can be most promising targets for cancer therapy

Rice University's nano-bio-chip 93% specific in detecting patients with premalignant lesions

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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