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Silky webs of spiders may hold secrets to repairing our skeletons

Some secrets to repairing our skeletons might be found in the silky webs of spiders, according to recent experiments guided by supercomputers. Scientists involved say their results will help understand the details of osteoregeneration, or how bones repair themselves.

20 Dec 2017

Clinical benefit of new cancer therapies may justify the expensive price

Researchers from the University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, selected to estimate the cost-effectiveness of the newly approved CAR-T therapies, have found the clinical benefit may justify the expensive price.

20 Dec 2017

Advances in BioAFM

AFM is quite a versatile technique and we see a great potential of this technology for life science applications. It is still fairly new in Bio community, however very well accepted not only as imaging tools but as a versatile instrument for nanomechanical measurements.

From Bruker Nano Surfaces and Metrology 19 Dec 2017

Researchers identify novel mechanism that protects from brain tumor

A group of researchers at the Spanish National Cancer Research Centre have identified a protein called RanBP6 as a new regulator of EGFR. In a paper published in Nature Communications they show how silencing of RanBP6 promoted glioma growth, by upregulating EGFR expression.

18 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Understanding how cancer cells are able to metastasize -- migrate from the primary tumor to distant sites in the body -- and developing therapies to inhibit this process are the focus of many laboratories around the country.

18 Dec 2017

Excessive copper in diabetes impedes ability to make new blood vessels

It's a metal we worry thieves will steal from our air conditioners or power lines, but inside our bodies too much copper can result in a much larger loss.

18 Dec 2017

Diabetes patients least likely to follow medical advice regarding medication due to side effects

Diabetes patients who take the most commonly prescribed diabetes drug, metformin, are the least likely to follow medical advice regarding their medication due its side effects, a new article in the journal Diabetes, Obesity and Metabolism reports.

18 Dec 2017

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

CANCER RESEARCH Danish researchers have just presented a previously unknown mechanism that inhibits the ability of cells to develop into cancer cells. Their findings have important implications for the understanding of how cancer starts, and how to improve the treatment of illness in the future.

15 Dec 2017

Researchers examine human mutations' impact on therapeutic effect of medicine

Every person has a unique DNA sequence in their genome. Now researchers from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge have tried to quantify what these differences in the genome mean in the context of the genes targeted by drugs.

15 Dec 2017

Scientists create atomic scale map that tracks how brain signals connect to neurons

Scientists at Johns Hopkins have used supercomputers to create an atomic scale map that tracks how the signaling chemical glutamate binds to a neuron in the brain. The findings, say the scientists, shed light on the dynamic physics of the chemical's pathway, as well as the speed of nerve cell communications.

15 Dec 2017

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

A fusion gene is a single composite gene that is the result of the combination of two formerly independent genes. Researchers from Kumamoto University, Japan have determined that a particular fusion gene has a tendency to be found in cutaneous squamous cell carcinoma (cSCC) lesions on skin exposed frequently to the sun.

14 Dec 2017

People diagnosed with schizophrenia or bipolar disorder may actually have treatable condition

Researchers at Houston Methodist believe that a significant number of people diagnosed with schizophrenia or bipolar disorder may actually have a treatable immune system condition.

14 Dec 2017

Human ‘common cold’ virus kills healthy chimpanzees in Uganda

In the wild, chimpanzees face any number of dire threats, ranging from poachers to predators to deforestation.

13 Dec 2017

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

A new study shows that attaching antibody-like RNA nanoparticles to microvesicles can deliver effective RNA therapeutics such as small interfering RNA specifically to cancer cells.

13 Dec 2017

New insights into mosquito sex protein could provide strategies to control diseases

If you thought the sex lives of humans were complicated, consider the case of the female Aedes aegypti mosquito, bringer of Zika, dengue, and yellow fever: She mates but once, in seconds and on the wing, with one lucky male; spurns all further advances from other potential suitors; and stores enough sperm from that single encounter to lay more than 500 eggs, which she nourishes with the blood of human hosts.

13 Dec 2017

Researchers adopt new approach to treating advanced prostate cancer

Scientists have proposed a new approach to preventing the proliferation of prostate tumor cells that are no longer responding to treatment. Prostate cancer can usually be cured via surgical removal of the tumor and/or the use of radiotherapy, but in one-fifth of cases, patients also require treatment with drugs to continue removing tumor cells. However, these drugs are only effective for up to three years, after which the cancer continues to develop.

13 Dec 2017

Researchers discover new way to attack drug-resistant prostate cancer cells

In most cases, prostate cancer is cured by surgical removal of the tumor and/or by radiotherapy. However, 20% of patients will need treatment to remove tumor cells but this treatment ceases to be effective after two or three years and the cancer develops further.

13 Dec 2017

UQ researchers create new and improved version of ‘love hormone’

A new and improved version of the ‘love hormone’ oxytocin has been developed by University of Queensland researchers.

13 Dec 2017

Death receptors in the blood can help measure risk of cardiovascular diseases, type 2 diabetes

Researchers at Lund University in Sweden have found that the presence of death receptors in the blood can be used to directly measure the risk of developing cardiovascular diseases and type 2 diabetes.

11 Dec 2017

Receptor News and Research

Silky webs of spiders may hold secrets to repairing our skeletons

Clinical benefit of new cancer therapies may justify the expensive price

Advances in BioAFM

Researchers identify novel mechanism that protects from brain tumor

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

Researchers identify mechanism that regulates signaling events leading to cancer metastasis

Excessive copper in diabetes impedes ability to make new blood vessels

Diabetes patients least likely to follow medical advice regarding medication due to side effects

Researchers reveal previously unknown mechanism that inhibits cells' ability to develop into tumors

Researchers examine human mutations' impact on therapeutic effect of medicine

Scientists create atomic scale map that tracks how brain signals connect to neurons

Fusion gene may be found in cSCC lesions on skin exposed frequently to the sun

People diagnosed with schizophrenia or bipolar disorder may actually have treatable condition

Human ‘common cold’ virus kills healthy chimpanzees in Uganda

Researchers use RNA nanotechnology to program exosomes for delivering effective cancer therapies

New insights into mosquito sex protein could provide strategies to control diseases

Researchers adopt new approach to treating advanced prostate cancer

Researchers discover new way to attack drug-resistant prostate cancer cells

UQ researchers create new and improved version of ‘love hormone’

Death receptors in the blood can help measure risk of cardiovascular diseases, type 2 diabetes

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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