Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Antidepressants can increase risk of C. difficile infection in depressed patients

Adults with depression and who receive certain types of anti-depressants have an increased risk of developing Clostridium difficile, a costly and serious hospital-associated infection, according to a new University of Michigan Health System study.

8 May 2013

Peripheral neuropathic pain patch treatments: an interview with Anne Hodgkins, Astellas Pharma

Peripheral neuropathic pain is caused by lesion or disease to the peripheral somatosensory nervous system. Nerve damage that can lead to peripheral neuropathic pain can happen as a result of a range of different diseases, medications or traumatic injuries.

8 May 2013

Brain scan studies may provide clues about how the device improves depression

For nearly a decade, doctors have used an implanted electronic stimulator to treat severe depression in people who don't respond to standard antidepressant therapy.

8 May 2013

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Electroconvulsive therapy (ECT) is the most effective acute treatment for severe major depression. However, even with newer forms of ECT, there remains a significant risk of adverse cognitive effects, particularly memory problems.

7 May 2013

Neuroperspective reviews status and prospects of therapeutics for Parkinson's disease

NI Research, the leading publisher of independent research on the neurotherapeutics industry, has released the May issue of NeuroPerspective, which reviews the status and prospects of therapeutics for Parkinson's.

7 May 2013

34% of all adverts for antidepressants are misleading by industry's self-regulation system

The new feature of the antidepressant drugs of the 1990s was that they had milder side-effects than their predecessors. Combined with aggressive marketing, this meant that annual sales in Sweden increased from just under EUR 18 million to over EUR 100 million in the space of just a few years.

6 May 2013

Research finds no increased risk of abnormal heart rhythms despite FDA warning against citalopram

The U.S. Food and Drug Administration's warning that high doses of the antidepressant citalopram can cause potentially serious abnormal heart rhythms might be doing more harm than good.

4 May 2013

SSRIs associated with increased risk of bleeding, transfusion, readmission and death

Selective serotonin reuptake inhibitors (SSRIs) - among the most widely prescribed antidepressant medications - are associated with increased risk of bleeding, transfusion, hospital readmission and death when taken around the time of surgery, according to an analysis led by researchers at UC San Francisco and Baystate Medical Center in Springfield, Mass.

30 Apr 2013

Post-stroke depression increases risk of suicide and mortality

Antidepressant medications known as SSRIs, such as fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), are effective when given to stroke patients as a preventive measure, the physicians write in the journal Topics in Stroke Rehabilitation.

26 Apr 2013

Alkermes reports topline results from phase 2 study of ALKS 5461 drug for major depressive disorder

Alkermes plc (NASDAQ: ALKS) today announced positive preliminary topline results from a phase 2 study of ALKS 5461, its novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression.

22 Apr 2013

Long winter months impact tamoxifen treatment for breast cancer

For women diagnosed with a form of breast cancer known as estrogen receptor positive (ER+) breast cancer, tamoxifen is an essential drug used in the treatment and prevention of recurring breast cancer.

19 Apr 2013

Electroconvulsive therapy improves quality of life in patients with severe depression

Patients whose severe depression goes into remission for six months following electroconvulsive therapy report a quality of life similar to that of healthy individuals, researchers say.

16 Apr 2013

Researchers unravel dual role of tumor necrosis factor in TB

Tumor necrosis factor - normally an infection-fighting substance produced by the body- can actually heighten susceptibility to tuberculosis if its levels are too high.

12 Apr 2013

New paper examines some suggested descriptions of mental pain

When we think of pain we generally think of something that is related to our body. But there is a devastating form of pain that is not frequently acknowledged and is a topic of a paper by Eliana Tossani (University of Bologna) in the current issue of Psychotherapy and Psychosomatics.

5 Apr 2013

Antidepressant News and Research

Further Reading

Antidepressants can increase risk of C. difficile infection in depressed patients

Peripheral neuropathic pain patch treatments: an interview with Anne Hodgkins, Astellas Pharma

Brain scan studies may provide clues about how the device improves depression

New form of electroconvulsive therapy could prevent adverse cognitive side effects

Neuroperspective reviews status and prospects of therapeutics for Parkinson's disease

34% of all adverts for antidepressants are misleading by industry's self-regulation system

Research finds no increased risk of abnormal heart rhythms despite FDA warning against citalopram

SSRIs associated with increased risk of bleeding, transfusion, readmission and death

Post-stroke depression increases risk of suicide and mortality

Alkermes reports topline results from phase 2 study of ALKS 5461 drug for major depressive disorder

Long winter months impact tamoxifen treatment for breast cancer

Electroconvulsive therapy improves quality of life in patients with severe depression

Researchers unravel dual role of tumor necrosis factor in TB

New paper examines some suggested descriptions of mental pain

Researchers confirm effectiveness of spray that improves dry mouth

New born neurons as a therapeutic strategy: an interview with Mi-Hyeon Jang, Mayo Clinic in Rochester, Minnesota

Biological psychiatry shares progress in identifying genomic predictors of antidepressant response

Alarming report on persistent side effects of antidepressant drugs published online

SSRI antidepressants taken during pregnancy do not impact infant's growth over the first year

Study challenges role of serotonin in depression, opens possibilities for new therapies

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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