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Novel mechanism of PDHX acetylation linked to hepatocellular carcinoma progression

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

3 Mar 2025

Intermittent fasting cuts heart attack risk by preventing dangerous blood clots

Intermittent fasting may reduce the risk of blood clots and cardiovascular disease by inhibiting platelet activation.

2 Mar 2025

New study confirms GLP-1 medications are safe for mental health in diabetes

Researchers assess whether GLP-1 receptor agonists increase the risk of suicide, self-harm, or suicidal ideation in type 2 diabetes patients.

2 Mar 2025

Researchers uncover how brain tumors reprogram neutrophils to hinder cancer treatment

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.

2 Mar 2025

Scientists develop fenugreek-based nanoparticles to enhance diabetes drug effectiveness

Researchers explored L-arginine-loaded lipid nanoparticles from fenugreek seed oil, finding they enhance drug stability and bioavailability, showing promise for diabetes treatment.

2 Mar 2025

Review sheds light on the mechanistic role of long non-coding RNAs in liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a global health challenge, affecting nearly 30% of adults worldwide.

28 Feb 2025

Understanding the impact of SLC transporters on liver disease progression

Hepatic steatosis, often triggered by non-alcoholic fatty liver disease (NAFLD), is a leading cause of liver dysfunction globally, affecting approximately 30% of the population.

28 Feb 2025

New discovery sheds light on energy crisis in children with TANGO2 deficiency

Researchers studying a protein linked to a rare, severe disease have made a discovery that sheds light on how cells meet their energy needs during a severe metabolic crisis.

28 Feb 2025

Do sugar substitutes really help? New research reveals their impact on metabolism and gut health

Low and no-calorie sweeteners (LNCSs) help reduce sugar intake, but their long-term effects on metabolism, gut health, and insulin response remain under investigation. Ongoing research explores their safety, effectiveness, and regulatory landscape.

27 Feb 2025

Artificial sweeteners may reduce metformin’s effectiveness in weight and glucose control

Drinking artificially sweetened beverages may reduce metformin’s effectiveness in young patients with obesity and prediabetes, but a larger study is needed to confirm these findings.

27 Feb 2025

New low-cost tool could revolutionize type 2 diabetes treatment

Millions of people with type 2 diabetes could receive better treatment thanks to a new, simple low-cost tool, according to groundbreaking research announced today at the Diabetes UK Professional Conference 2025 and published in the Lancet.

26 Feb 2025

Review: Artificial intelligence is shaping the future of diabetes care

The global incidence and prevalence of diabetes continue to rise, increasing rates of associated disability and mortality while imposing a substantial economic burden.

26 Feb 2025

Culturally relevant interventions crucial for addressing Type 2 diabetes in Indigenous youth

Culturally appropriate programs that build on the strengths and knowledge of Indigenous communities are crucial for reducing the burden of Type 2 diabetes among young people, a University of Queensland study has found.

25 Feb 2025

Why life expectancy gains in Europe stalled—and how some countries stayed ahead

Life expectancy gains in Europe slowed after 2011, with the COVID-19 pandemic further accelerating declines—while some countries maintained progress through sustained public health policies.

25 Feb 2025

Water-only fasting boosts human growth hormone without weight loss

Fasting for 24 hours increases human growth hormone (HGH) levels independently of weight loss, with individuals with lower baseline HGH experiencing the most significant increases. The study suggests metabolic benefits from fasting, particularly for those with lower HGH levels.

25 Feb 2025