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Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

The results of a study by researchers at the University of Texas Medical Branch may pave the way for a new medicine delivery system that could reduce the incidence of pre-term labor and premature birth by allowing physicians to treat the 'fetus as the patient'.

22 Jan 2021

Stanford study identifies a key factor in mental aging

Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.

20 Jan 2021

Researchers investigate protein phosphatase to identify new treatments for cancer, other diseases

The abundant presence of an enzyme known as low molecular weight protein tyrosine phosphatase (LMWPTP) in tumor cells has long been considered an indicator of cancer aggressiveness and metastatic potential.

13 Jan 2021

Antibody-Fc-mediated innate immunity shapes COVID-19 severity

A short paper that appeared recently on the preprint bioRxiv server pointed to a link between specific characteristics of anti-SARS-CoV-2 antibodies associated with the severity of COVID-19.

12 Jan 2021

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

A recent study has found that extracellular vimentin can bind to SARS-CoV-2 spike protein in vitro, and antibodies against vimentin can decrease virus infectivity by up to 80%. This suggests vimentin could aid the virus’s binding to host cells and help in infection.

11 Jan 2021

Tetherin downregulation by SARS-CoV-2 enhances viral spread

A new preprint research paper published on the bioRxiv server describes the role of a host protein called tetherin in the spread of the novel coronavirus.

10 Jan 2021

Biomarkers can predict how genetically identical cells behave differently under stress

A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study.

8 Jan 2021

CytoDel successfully delivers neuronal antibody in animal models of botulism

CytoDel, Inc., a privately-held corporation, today announces the publication of preclinical data on the Company's lead product, Cyto-111, in the peer-reviewed journal, Science Translational Medicine. The complete text of the article titled, "Neuronal Delivery of Antibodies has Therapeutic Effects in Animal Models of Botulism," can be found here.

7 Jan 2021

Study reveals molecular machinery that regulates membrane association of Arf proteins

The small GTPases of the ADP-ribosylation factor (Arf) family are key initiators of various physiological processes including secretion, endocytosis, phagocytosis, and signal transduction. Arf family proteins function to mediate the recruitment of cytosolic effectors to specific subcellular compartments.

7 Jan 2021

Heat treatment during chemotherapy is more effective at destroying cancer cells

Heating up cancer cells while targeting them with chemotherapy is a highly effective way of killing them, according to a new study led by UCL researchers.

5 Jan 2021

Study shows how sodium ions drive glutamate transport in the central nervous system

Scientists from the MIPT Research Center for Molecular Mechanisms of Aging and Age-Related Diseases have joined forces with their colleagues from Forschungszentrum Jülich, Germany, and uncovered how sodium ions drive glutamate transport in the central nervous system.

22 Dec 2020

Researchers create new polymer to deliver DNA and RNA-based therapies for diseases

University of Minnesota Twin Cities researchers in the Department of Chemistry have created a new polymer to deliver DNA and RNA-based therapies for diseases.

21 Dec 2020

Scientists develop an enhanced version of phototoxic protein

Scientists from Skoltech, the Institute of Bioorganic Chemistry of RAS, and the London Institute of Medical Sciences (LMS) have developed an enhanced version of SuperNova, a genetically encoded phototoxic synthesizer, that helps control intracellular processes by light exposure.

17 Dec 2020

Errant DNA triggers immune system response against cancer

DNA that ends up where it doesn't belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate.

17 Dec 2020

Scientists examine the virulent potential of Listeria strains in pigs

Researchers from the CEU Cardenal Herrera University (CEU UCH) of Valencia, the University of Cordoba and the Pasteur Institute of Paris, have conducted a study to determine the virulent potential of strains of the Listeria monocytogenes bacteria in pigs in Spain.

17 Dec 2020

Intracellular News and Research

Treating 'fetus as the patient' could reduce the incidence of pre-term labor and premature birth

Stanford study identifies a key factor in mental aging

Researchers investigate protein phosphatase to identify new treatments for cancer, other diseases

Antibody-Fc-mediated innate immunity shapes COVID-19 severity

Vimentin could be a major co-factor that aids SARS-CoV-2 infection

Tetherin downregulation by SARS-CoV-2 enhances viral spread

Biomarkers can predict how genetically identical cells behave differently under stress

CytoDel successfully delivers neuronal antibody in animal models of botulism

Study reveals molecular machinery that regulates membrane association of Arf proteins

Heat treatment during chemotherapy is more effective at destroying cancer cells

Study shows how sodium ions drive glutamate transport in the central nervous system

Researchers create new polymer to deliver DNA and RNA-based therapies for diseases

Scientists develop an enhanced version of phototoxic protein

Errant DNA triggers immune system response against cancer

Scientists examine the virulent potential of Listeria strains in pigs

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

New screening platform can be used to discover more effective drugs for type 1 diabetes

D614G mutation promotes lysosomal trafficking of SARS-CoV-2 spike protein

New model shows how bacteria behave in multiple scenarios with common spatial patterns

New consortium aims to understand principles underlying the formation of coronaviruses

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