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Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

Damage to the autism-associated gene Dyrk1a, sets off a cascade of problems in developing mouse brains, resulting in abnormal growth-factor signaling, undergrowth of neurons, smaller-than-average brain size, and, eventually, autism-like behaviors, a new study from Scripps Research, Florida, finds.

8 Apr 2021

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Curing cancer has been the dream of countless doctors and researchers over the decades. Yet some types of cancer, whether because they affect relatively few people or lack influential advocates, receive less attention and funding than others.

7 Apr 2021

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Scientists from the Genomic Integrity and Structural Biology Group led by Rafael Fernández-Leiro at the Spanish National Cancer Research Centre have discovered how certain proteins ensure the repair of errors introduced into the DNA during its replication.

6 Apr 2021

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann's recent work on the plant Arabidopsis thaliana has uncovered surprising answers.

5 Apr 2021

New mini-microscope enables imaging of complex brain functions in freely moving mice

Researchers from the University of Minnesota Twin Cities College of Science and Engineering and Medical School have developed a unique head-mounted mini-microscope device that allows them to image complex brain functions of freely moving mice in real time over a period of more than 300 days.

5 Apr 2021

New RNA-sequencing method can help detect numerous modified small RNAs

A team led by a biomedical scientist at the University of California, Riverside, has developed a new RNA-sequencing method-- "Panoramic RNA Display by Overcoming RNA Modification Aborted Sequencing," or PANDORA-seq -- that can help discover numerous modified small RNAs that were previously undetectable.

5 Apr 2021

Olympus announces global image of the year award winners

Olympus unveiled the winners of their second Global Image of the Year Life Science Light Microscopy Award, an annual competition that recognizes the best in life science imaging.

From Evident Corporation - Life Sciences 5 Apr 2021

RNA-binding cylinders inhibit SARS-CoV-2 replication in vitro

Research led by Michael J. Hannon from the University of Birmingham, UK, finds metallo-supramolecular helicates (cylinders) binding to untranslated regions of SARS-CoV-2 suppresses viral replication. The untranslated regions (UTR) of the viral genome could serve as drug targets for antiviral treatment.

5 Apr 2021

Soft X-ray microscopy shows how viral pathogens penetrate human cells

How do viral pathogens succeed in penetrating human cells? Which cellular mechanisms do they use to multiply efficiently and, in doing so, how do they change the structure of their host cell? These questions are the focus of a pan-European research project called "Compact Cell-Imaging Device" (CoCID), in which Heidelberg scientists are playing a major role.

31 Mar 2021

Fat grafting shows potential to help cancer patients with radiation-induced skin injury

As cancer survival rates improve, more people are living with the aftereffects of cancer treatment. For some patients, these issues include chronic radiation-induced skin injury - which can lead to potentially severe cosmetic and functional problems.

30 Mar 2021

Researchers identify new targets for minimizing tooth sensitivity to cold

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels.

27 Mar 2021

UVA scientists identify a potential way to prevent heart attacks and strokes

Scientists at the University of Virginia School of Medicine have identified a potential way to head off heart attacks and strokes by strengthening the fibrous caps overlying atherosclerotic plaques that naturally accumulate inside our arteries.

27 Mar 2021

Grundium Press Release: 1000th Microscope Scanner

On March 24th, 2021 Grundium manufactured its 1000th microscope scanner.

From Grundium 26 Mar 2021

Bruker light-sheet microscopes at major comprehensive cancer center

Bruker Corporation (Nasdaq: BRKR), a leading supplier of single-plane illumination microscopy (SPIM) technology for research on live cells and cleared biological samples, today announced that two Luxendo MuVi™ and LCS SPIM™ light-sheet microscopes have been installed by Memorial Sloan Kettering Cancer Center (MSK).

From Bruker Nano Surfaces and Metrology 25 Mar 2021

Scientists produce high-resolution 3D image of sarcomere using electron cryo-tomography

Scientists have produced the first high-resolution 3D image of the sarcomere, the basic contractile unit of skeletal and heart muscle cells, by using electron cryo-tomography (cryo-ET).

25 Mar 2021

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

Of all the worlds still to be explored, among the most mysterious may be closest to home. Indeed, it may be right between your ears.

22 Mar 2021

Investments in life sciences can be appealing to many investors as vaccines are rolled out

The past twelve months have showcased the importance of medical developments like never before. Innovation in the life sciences sector has been headline news around the globe and all aspects of the healthcare system have been under the microscope.

22 Mar 2021

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.

19 Mar 2021

AI screenings of pap smears can detect precursors to cervical cancer

Using artificial intelligence and mobile digital microscopy, researchers hope to create screening tools that can detect precursors to cervical cancer in women in resource-limited settings.

17 Mar 2021

Study investigates activity of enzymes immobilized on gold nanoparticles controlled by infrared laser irradiation

The activity of enzymes in industrial processes, laboratories, and living beings can be remotely controlled using light. This requires their immobilization on the surface of nanoparticles and irradiation with a laser. Near-infrared light can penetrate living tissue without damaging it.

17 Mar 2021

Microscope News and Research

Mutations to autism-associated gene cause a cascade of problems in developing mouse brains

New grant to Harvard Medical School is boosting efforts to understand and combat rare cancers

Scientists use cryo-electron microscopy to unravel how 'guardian' of the genome works

Researchers use single-cell RNA sequencing technologies to track cellular development in leaves

New mini-microscope enables imaging of complex brain functions in freely moving mice

New RNA-sequencing method can help detect numerous modified small RNAs

Olympus announces global image of the year award winners

RNA-binding cylinders inhibit SARS-CoV-2 replication in vitro

Soft X-ray microscopy shows how viral pathogens penetrate human cells

Fat grafting shows potential to help cancer patients with radiation-induced skin injury

Researchers identify new targets for minimizing tooth sensitivity to cold

UVA scientists identify a potential way to prevent heart attacks and strokes

Grundium Press Release: 1000th Microscope Scanner

Bruker light-sheet microscopes at major comprehensive cancer center

Scientists produce high-resolution 3D image of sarcomere using electron cryo-tomography

Virginia Tech neuroscientist uses NIH grant to understand astrocytic processes in the healthy brain

Investments in life sciences can be appealing to many investors as vaccines are rolled out

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

AI screenings of pap smears can detect precursors to cervical cancer

Study investigates activity of enzymes immobilized on gold nanoparticles controlled by infrared laser irradiation

Industry Focus eBook - Life Science Microscopy (2nd Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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