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Researchers study the digestion process of drug-loaded DNA nanostructures in real time

DNA nanotechnology - the research field using DNA molecules as building material - has developed rapidly during recent years and enabled the construction of increasingly complex nanostructures.

2 Mar 2021

New 'E-Morph' test method replaces animal experiments to detect hormone-like effects

Endocrine disruptors (EDs) are hormone-like substances that can have undesirable effects on health. For example, chemicals can increase the risk of breast cancer if they act in a manner similar to the female sex hormone estrogen.

26 Feb 2021

New approach harnesses disease-causing proteins to combat cancer

Over many decades now, traditional drug discovery methods have steadily improved at keeping diseases at bay and cancer in remission. And for the most part, it's worked well.

26 Feb 2021

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

The eukaryotic cell is the basic unit of animals and plants. At the microscope, it looks highly structured and subdivided in many membrane-bound compartments.

25 Feb 2021

Researchers discover a mechanism linked to stem cell aging

As people get older, their neural stem cells lose the ability to proliferate and produce new neurons, leading to a decline in memory function.

24 Feb 2021

Microfluidic chip and AI-powered automated microscope help measure hemoglobin levels

One of the most performed medical diagnostic tests to ascertain the health of patients is a complete blood count, which typically includes an estimate of the hemoglobin concentration.

24 Feb 2021

Researchers use powerful X-rays to analyze brain tissues of schizophrenia patients

Schizophrenia, a chronic, neurological brain disorder, affects millions of people around the world. It causes a fracture between a person's thoughts, feelings and behavior.

24 Feb 2021

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

The remarkable genetic scissors called CRISPR/Cas9, the discovery that won the 2020 Nobel Prize in Chemistry, sometimes cut in places that they are not designed to target.

23 Feb 2021

Propranolol can be used to treat cerebral cavernous malformations

Propranolol, a drug that is efficacious against infantile haemangiomas ("strawberry naevi", resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterized by misshapen blood vessels in the brain and elsewhere.

23 Feb 2021

Scientists reveal the structure of glutamate transporter in our cells

For the first time, researchers have found one of the most important molecular machines in our cells uses a ‘twisting elevator’ mechanism, solving a mystery of how it transports crucial chemical signals from one cell to another.

18 Feb 2021

Scientists reveal the shape of glutamate transporter in human cells

A University of Sydney-led international team of scientists has revealed the shape of one of the most important molecular machines in our cells the glutamate transporter, helping to explain how our brain cells communicate with one another.

18 Feb 2021

New collaborative project to study the complex roles of lipids in health, disease

A University of Minnesota-Mayo Clinic partnership has joined with the Zooniverse citizen scientist platform and the Francis Crick Institute in London to leverage world-leading expertise in microscope imaging with the power of citizen science to study the relationship between structure and function in biology to better understand health and disease.

17 Feb 2021

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

A team of researchers used several assays, atomic force microscopy, and simulations to determine that the N501Y mutation in the virus’s receptor-binding domain (RBD) increased the interaction of the virus with the angiotensin-converting enzyme 2 (ACE2) receptor.

17 Feb 2021

Study shows how SARS-CoV-2 uses an immune system defense for replication

The immune system actually wants to fight SARS-CoV-2 with antiviral signaling molecules. But a research team from Charité and MDC has now shown how such a signaling molecule can promote the replication of the virus. The results have been published in the journal EMBO Molecular Medicine.

17 Feb 2021

Researchers discover the role of a gene involved in cardiac rhythm

Researchers have used the zebrafish (Danio rerio) to identify the role of a gene involved in cardiac rhythm, which could help explain the fundamentals of what it takes to make a human heartbeat.

16 Feb 2021

Researchers identify key genetic changes in interstitial kidney tissue of people with diabetes

Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease.

16 Feb 2021

Birds keep a layer of soft, fluffy down feathers to regulate body temperature

Feathers are a sleek, intricate evolutionary innovation that makes flight possible for birds, but in addition to their stiff, aerodynamic feathers used for flight, birds also keep a layer of soft, fluffy down feathers between their bodies and their outermost feathers to regulate body temperature.

15 Feb 2021

Microscope News and Research

Researchers study the digestion process of drug-loaded DNA nanostructures in real time

New 'E-Morph' test method replaces animal experiments to detect hormone-like effects

New approach harnesses disease-causing proteins to combat cancer

Process of molecular sorting emerges from combination of two spontaneous mechanisms, indicates study

Researchers discover a mechanism linked to stem cell aging

Microfluidic chip and AI-powered automated microscope help measure hemoglobin levels

Researchers use powerful X-rays to analyze brain tissues of schizophrenia patients

DNA origami used to analyze the ultra-fast movements of CRISPR enzymes

Propranolol can be used to treat cerebral cavernous malformations

Scientists reveal the structure of glutamate transporter in our cells

Scientists reveal the shape of glutamate transporter in human cells

New collaborative project to study the complex roles of lipids in health, disease

New N501Y SARS-CoV-2 mutations increase binding to host cell receptor

Study shows how SARS-CoV-2 uses an immune system defense for replication

Researchers discover the role of a gene involved in cardiac rhythm

Researchers identify key genetic changes in interstitial kidney tissue of people with diabetes

Birds keep a layer of soft, fluffy down feathers to regulate body temperature

Male fruit flies win genetic race with rivals in post-mating fertilization game

Researchers map the mechanism behind cellular communication

Using a smartphone-based microscope for detecting single molecules and diagnosing diseases

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