Mitochondria News and Research

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Ludwig study uncovers a nutritional approach to improve cancer immunotherapy

A Ludwig Cancer Research study has uncovered a mechanism by which the tumor's harsh internal environment sabotages T lymphocytes, leading cellular agents of the anticancer immune response.

5 Oct 2020

Induction of acute senescence may be a necessary process in hemorrhagic shock

It's called senescence, when stressed cells can no longer divide to make new cells, and it's considered a factor in aging and in some diseases.

29 Sep 2020

Researchers solve the mystery of how giant molecular proton pump works

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a proton gradient that powers the generation of ATP, the cell's fuel.

24 Sep 2020

Overactivation of fructose made in the brain may drive Alzheimer's disease

New research released from the University of Colorado Anschutz Medical Campus proposes that Alzheimer's disease may be driven by the overactivation of fructose made in the brain.

23 Sep 2020

Light therapy is safe and can benefit patients with TBI, shows study

Light therapy is safe and has measurable effects in the brain, according to a pioneering study by researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH).

23 Sep 2020

Parkinson's disease diagnosed after SARS-CoV-2

As the COVID-19 pandemic continues to spread, new and unusual chronic sequelae of the disease are cropping up in many medical practices. Now, a new case paper published in The Lancet in September 2020 describes a case of new-onset Parkinson's disease following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

22 Sep 2020

Diabetes leads to drastic reduction in the kidney's potential to clean itself

The kidneys often become bulky and dysfunctional in diabetes, and now scientists have found that one path to this damage dramatically reduces the kidney's ability to clean up after itself.

22 Sep 2020

New national research and training hub at UW-Madison could transform medicine

A national research initiative announced today will place the University of Wisconsin-Madison at the forefront of a revolution in imaging fostered by cryo-electron microscopy and cryo-electron tomography - technologies that can illuminate life at the atomic scale.

22 Sep 2020

Cannabinoids cause changes in the brain that leads to deficiencies in social interaction

The nervous system comprises neurons and glial cells (glia signifies "glue"). Astrocytes are the most abundant among the glial cells.

19 Sep 2020

Study identifies a cell-cleaning system that is key to keeping a healthy heart

Researchers of the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a cell-cleaning system that is key to keeping a healthy heart.

15 Sep 2020

Researchers investigate the effects of endurance training on cellular respiration

In obese individuals, endurance exercise improves fitness and increases the number of mitochondria * and cellular respiration in skeletal muscles.

10 Sep 2020

Scientists solve decades old mystery of key molecule that fuels mitochondria

Penn Medicine researchers have solved a decades old mystery around a key molecule fueling the power plant of cells that could be exploited to find new ways to treat diseases, from neurodegenerative disorders to cancer.

10 Sep 2020

Antibody-mediated platelet death linked to COVID-19 severity

A new study by University of Tuebingen researchers shows the strong association between platelet apoptosis and the thrombotic manifestations that may underlie critical COVID-19 illness.

7 Sep 2020

Important research on SARS-CoV-2 proteins using proximity labeling

A team of Canadian scientists has recently discovered a wide-range interaction between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and host proteins using proximity-dependent biotinylation approaches.

7 Sep 2020

New grant supports research into diabetic kidney disease and COVID-19

Mater and University of Queensland Researcher Dr Mitchell Sullivan has been awarded a 2020 Advance Queensland Industry Research Fellowship from the Queensland Government to fund his research into diabetic kidney disease and COVID-19.

3 Sep 2020

Massive cellular energy audit identifies genes that drive energy production, consumption

TK Adenosine triphosphate, or ATP, is the cellular energy currency that is as valuable to the human body as the dollar is to the US economy.

28 Aug 2020

New group of Chlamydiae have hydrogen-producing genes that help them survive without oxygen

An international team of researchers has discovered a new group of Chlamydiae - Anoxychlamydiales - living under the ocean floor without oxygen.

27 Aug 2020

Researchers identify how promising therapy may work to improve adverse effects of NAFLD

A team led by researchers at Massachusetts General Hospital (MGH) has taken an important step forward in the goal of developing a potential treatment for non-alcoholic fatty liver disease (NAFLD), the most common form of chronic liver disease.

26 Aug 2020

Congenital disorder of fat metabolism can cause chronic hyperreaction of the immune system

Scientists at the University of Bonn identify previously unknown disease mechanism. A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system.

24 Aug 2020

SARS-CoV-2 ORF9c responsible for immune evasion and efficient infection of host

A recent study by researchers at the Sanford Burnham Prebys Medical Discovery Institute and the University of California San Francisco and published on the preprint server bioRxiv in August 2020 shows that a protein encoded by the subgenomic sequence ORF9c of SARS-CoV-2 is responsible for the low antiviral response in infected humans, enabling the successful replication of the virus in the host.

21 Aug 2020