Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Cancer drops sparse chemical hints of its presence early on, but unfortunately, many of them are in a class of biochemicals that could not be detected thoroughly, until now.

8 May 2018

Illinois Department of Commerce and Economic Opportunity approves development of new research park in North Chicago

The Illinois Department of Commerce and Economic Opportunity recently approved the expansion of a state enterprise zone, designed to stimulate economic growth and community revitalization at the local level, to include North Chicago, IL-based

28 Apr 2018

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient to patient, a discovery that adds to a growing base of knowledge important for developing more effective precision therapies.

27 Apr 2018

Gene related to high fatality could be used as biomarker in patients with P. aeruginosa infection

Researchers discovered an easily measured gene linked to a high fatality rate, which could be used as a novel prognostic biomarker in patients with a Pseudomonas aeruginosa (P. aeruginosa) bloodstream infection, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases.

23 Apr 2018

Researchers identify target gene in P. aeruginosa infection

Researchers have discovered a gene linked to fatal outcomes in Pseudomonas aeruginosa (P. aeruginosa) infection that could be used as a novel prognostic biomarker and treatment target.

23 Apr 2018

Role of UBE3A enzyme in Angelman syndrome

The group, led by the Ikerbasque professor Ugo Mayor of the UPV/EHU's Department of Biochemistry and Molecular Biology, has just published in the journal Human Molecular Genetics an explanation of the mechanisms affected by Angelman syndrome.

20 Apr 2018

Researchers use 'top-down proteomics' strategy to get new insights into cancer

When a RAS gene operates normally, it acts as an on/off switch for cell signaling to control cell proliferation. But when the gene mutates, the switch jams into the "on" position, allowing cells to proliferate uncontrollably.

18 Apr 2018

Expedeon relocates to Cambridge as part of integration into SYGNIS Group

SYGNIS AG today announced the completion of the relocation of its subsidiary company, Expedeon, into the Company’s existing facilities in Cambridge, UK.

16 Apr 2018

SYGNIS AG acquires bioconjugation specialist Expedeon

Expedeon, a specialist provider of bioconjugation products and services, has announced it has been fully acquired by Sygnis AG, for EUR 8 million in cash and 3.5 million in shares.

16 Apr 2018

Dietary fats play varied roles in disease

This month's issue of the Journal of Lipid Research features studies examining how fats in the diet affect health, including whether the ketogenic diet is a reasonable cancer therapy; how the type of unsaturated fats in a mouse's chow affects inflammation; and how cells respond to nutrient signals.

12 Apr 2018

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Intestinal bacteria have attracted recent attention since they were discovered to influence various physiological functions and diseases in humans.

10 Apr 2018

Scientists develop indices that provide information about prognosis of cancers

Researchers from the School of Medicine in Ribeirão Preto, at the University of São Paulo, in collaboration with international groups, have developed indices that provide information about the prognosis of cancers, aid in the choice of the most appropriate therapy to be used and identify potential targets for the development of new drugs.

6 Apr 2018

Insilico to present recent advances in AI for aging biomarkers and age management research

Insilico Medicine, a Baltimore-based next-generation artificial intelligence company specializing in the application of deep learning for drug discovery, biomarker development and aging research, is pleased to announce the presentation of its Director of Drug Discovery, Dr. Ivan Ozerov, at the 24th Clinical Applications for Age Management Medicine Conference, April 27, 2018, organized by Age Management Medicine Group.

6 Apr 2018

Stable proteins in the brain offer clues to long-term memory and learning in mice

In the tiny brain space where two nerve cells meet, chemical and electric signals shuttle back and forth, a messaging system that ebbs and flows in those synaptic spaces, sometimes in ways that scientists believe aid and abet learning and memory.

3 Apr 2018

Students propose innovative concept to diagnose infectious diseases

Imagine a small paper device that can rapidly reveal from a drop of blood whether an infection is bacterial or viral. The device could help reduce the overuse of antibiotics – which kill bacteria, not viruses. Misuse of antibiotics has led to antimicrobial resistance, a growing global public health issue.

28 Mar 2018

Changing schedules of targeted therapy for melanoma could improve outcomes

Skin melanoma, a particularly insidious cancer, accounts for the vast majority skin cancer deaths and is one of the most common cancers in people under 30.

26 Mar 2018

Protein profiling reveals new prostate cancer mechanisms

A study by the University of Tampere in Finland used protein profiling to find new prostate cancer mechanisms that are not shown by aberrations at the genomic level. Several new potential biomarkers of prostate cancer were also found.

21 Mar 2018

Study validates Xpresys Lung 2 for differential diagnosis of early stage lung cancer

Integrated Diagnostics today announced the e-publication of full results of a large prospective clinical trial validating its Xpresys Lung 2 in the peer-reviewed medical journal CHEST¸ the official journal of the American College of Chest Physicians, titled: Assessment of Plasma Proteomics Biomarker’s Ability to Distinguish Benign From Malignant Lung Nodules: Results of the PANOPTIC trial.

12 Mar 2018

New marker involved in lymphatic system linked to increased risk of heart failure

Researchers at Lund University in Sweden have found a new marker in the blood that is associated with an increased risk of heart failure.

7 Mar 2018

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), led by Dr. Alicia G. Arroyo, have identified a function of a protease that could be targeted for the treatment of some infections and even tumor metastasis.

2 Mar 2018

Proteomics News and Research

Further Reading

New chemical trap catches trace glycoproteins, shows promise for targeted cancer treatments

Illinois Department of Commerce and Economic Opportunity approves development of new research park in North Chicago

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

Gene related to high fatality could be used as biomarker in patients with P. aeruginosa infection

Researchers identify target gene in P. aeruginosa infection

Role of UBE3A enzyme in Angelman syndrome

Researchers use 'top-down proteomics' strategy to get new insights into cancer

Expedeon relocates to Cambridge as part of integration into SYGNIS Group

SYGNIS AG acquires bioconjugation specialist Expedeon

Dietary fats play varied roles in disease

Researchers discover how intestinal bacteria can influence blood glucose and lipid concentrations

Scientists develop indices that provide information about prognosis of cancers

Insilico to present recent advances in AI for aging biomarkers and age management research

Stable proteins in the brain offer clues to long-term memory and learning in mice

Students propose innovative concept to diagnose infectious diseases

Changing schedules of targeted therapy for melanoma could improve outcomes

Protein profiling reveals new prostate cancer mechanisms

Study validates Xpresys Lung 2 for differential diagnosis of early stage lung cancer

New marker involved in lymphatic system linked to increased risk of heart failure

Blockade of a protein increases surveillance activity of blood-patrolling monocytes, study shows

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