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Examining dopamine receptors in their natural environment

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

Advancements in the Optimization of Medical Accelerators

Radiotherapy is a way of treating cancer by means of radiation. In principle, that can be all different types of radiation. The commonly known types are X-rays or electron beams, which find very widespread application.

11 Jun 2020

Anticardiolipin antibodies and COVID-19

A new study has shown that anticardiolipin antibodies are associated with the novel coronavirus infection or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes COVID-19.

10 Jun 2020

Algorithm that analyzes MRI images could boost development of new arthritis therapies

An algorithm that analyses MRI images and automatically detects small changes in knee joints over time could be used in the development of new treatments for arthritis.

9 Jun 2020

Protease inhibition could help defeat SARS-CoV-2

As the COVID-19 pandemic caused by the coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continues to spread around the world, many researchers are studying epidemiological models to predict its propagation. As of yet, there are no effective vaccines that could counter the SARS- CoV-2 infection or drugs to treat COVID-19 disease

9 Jun 2020

COVID-19 produces lung inflammation in non-human primate experiments

A new study published on the online preprint server bioRxiv in June 2020 reports the successful use of three primate species to model the infection, pathogenesis, and clinical features associated with COVID-19. The research provides useful and immediately available models to test new vaccines and treatments.

9 Jun 2020

Inhibition of coronavirus spike protein binding to ACE2

A novel coronavirus, CoV-19, and a later phenotype CoV-2 were identified as the primary cause for severe acute respiratory syndrome (SARS CoV-2). The spike (S) protein of CoV-2 is one target for the development of a vaccine to prevent the viral entry into human cells. The inhibition of the direct interaction between ACE2 and the S-protein could provides a suitable strategy to prevent the membrane fusion of CoV-2 and the viral entry into human cells. Using MD simulations, we investigate the assembly process of a Coronavirus Spike protein fragment, the hexapeptide YKYRYL on the ACE2 receptor and its inhibitzory effect on the aggregation and activation of the CoV-2 spike receptor protein at the same receptor protein.

8 Jun 2020

Long-term care facilities are a major driver of total COVID-19 deaths

Long-term care facilities (LTCFs) are a major driver of total COVID-19 deaths. Reported today in the Journal of the American Geriatrics Society, Boston Medical Center (BMC) and Boston University School of Medicine (BUSM) geriatricians Rossana Lau-Ng, Lisa Caruso and Thomas Perls studied the past month's case and death data reported by the Massachusetts Department of Health's COVID-19 daily Dashboard along with data provided by the Kaiser Family Foundation and other countries.

5 Jun 2020

Natural molecules that stimulate dopamine production may help reverse Parkinson's disease

Investigators have identified two molecules naturally produced by the body that stimulate the production of dopamine, the molecule that is in short supply in the brains of patients with Parkinson's disease.

4 Jun 2020

AI can be used to expand the role of chest X-ray imaging in COVID-19 diagnosis

According to a recent report by Johns Hopkins Medicine researchers, artificial intelligence (AI) should be used to expand the role of chest X-ray imaging -- using computed tomography, or CT -- in diagnosing and assessing coronavirus infection so that it can be more than just a means of screening for signs of COVID-19 in a patient's lungs.

3 Jun 2020

Artificial intelligence may help study the structures and properties of unknown samples

Researchers at the Institute of Industrial Science, The University of Tokyo (UTokyo-IIS) used artificial intelligence to rapidly infer the excited state of electrons in materials.

3 Jun 2020

Novel 3D imaging technique could prove to be valuable for wide range of studies

A collaboration between Colorado State University and University of Illinois at Urbana-Champaign resulted in a new, 3D imaging technique to visualize tissues and other biological samples on a microscopic scale, with potential to assist with cancer or other disease diagnoses.

2 Jun 2020

Human waste could be used to create nitrogen-rich fertilizer

Researchers from Cornell University's College of Agriculture and Life Sciences and the Canadian Light Source at the University of Saskatchewan have proven it is possible to create nitrogen-rich fertilizer by combining the solid and liquid components of human waste.

2 Jun 2020