immunity News and Research

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Breakthrough model simulates human bone marrow function in the lab

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

31 Jan 2025

Gut-derived sugars: A potential game-changer for weight management and diabetes

Gut bacteria-produced exopolysaccharides (EPS) help regulate metabolism by modulating gut microbiota, promoting SCFA production, and improving glucose homeostasis. S. salivarius, a key EPS producer, shows potential for obesity and diabetes intervention.

30 Jan 2025

How your immune system ages: Scientists reveal key changes over a lifetime

Scientists mapped how the human immune system evolves from birth to old age, revealing key changes that influence health, disease resistance, and aging. Their immune age model could help predict immune health and guide early interventions.

30 Jan 2025

Study identifies six genetic regions associated with anterior uveitis

An international study led by the University of Oulu and Oulu University Hospital has identified six genetic regions associated with the inflammation of the eye's iris, also known as anterior uveitis.

30 Jan 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

New tool detects highly transmissible SARS-CoV-2 variants early

Researchers have developed a powerful tool that can detect variants of SARS-CoV-2 with high transmission potential before they become widespread.

29 Jan 2025

Is juicing good for your gut? Research shows surprising microbiome changes

Short-term fruit and vegetable juicing causes microbial shifts in the oral and gut microbiome, but these changes are mostly transient and return to baseline after 14 days.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025

Study uncovers distinct blood protein signature in children with Long COVID

Distinct protein profiles linked to inflammation and angiogenesis found in children with Long COVID, paving the way for improved diagnostics and therapies.

28 Jan 2025

Key immune cells required for tissue repair following liver injury

Our livers contain many different types of immune cells. New research by the team of Prof. Charlotte Scott (VIB-UGent Center for Inflammation Research) and colleagues now reveals that a specific activation state of one of these cell types is required for tissue repair following injury.

24 Jan 2025

New approach to treating ependymoma with leukemia drug

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk Cook Professor of Radiation Oncology at Harvard Medical School, is senior author of a new study in PNAS, Targeting EPHB2/ABL1 Restores Anti-Tumor Immunity in Preclinical Models of Ependymoma.

23 Jan 2025

Non-industrialized diet improves health and reduces disease risk

Researchers have found that a newly developed diet inspired by the eating habits of non-industrialised societies can significantly reduce the risk of a number of chronic diseases – and are to share recipes with the public.

23 Jan 2025

AGA releases updated guidelines on hepatitis B reactivation in patients on immunosuppressive drugs

The American Gastroenterological Association (AGA) has unveiled an updated clinical practice guideline in Gastroenterology addressing the prevention and management of hepatitis B virus reactivation (HBVr) in patients on immunosuppressive drugs.

23 Jan 2025

Researchers discover how location affects immune cells' role in fighting disease

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting disease.

22 Jan 2025

Study reveals how gut bacteria influence immune cell training and inflammation

A study led by David Sancho at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid reveals how an increase in intestinal permeability allows the natural gut bacteria to cross the intestinal barrier and reach the bone marrow, where they induce epigenetic changes-modifications that alter gene activity without affecting DNA sequence-in the stem cells that give rise to immune cells.

22 Jan 2025

Study sheds light on the dynamics of non-persistent HPV infections

Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a study published January 21st in the open-access journal PLOS Biology by Samuel Alizon of the National Centre for Scientific Research (CNRS), France, and colleagues.

21 Jan 2025