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Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

In a recent study published in the journal Molecular Therapy, researchers identified Bifonazole, an imidazole-based antifungal agent, to have potent activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using high-throughput screening of small molecules.

12 May 2022

Discovery of host co-factors necessary for SARS-CoV2 infection

A new study published in the journal EMBO Reports has reported on the shedding of two proteases, namely, ADAM10 and ADAM17, which aids in S protein-dependent molecular events.

11 May 2022

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Intestinal micro-biodiversity is important for maintaining colorectal and general health. Imbalance in this microenvironment can result in chronic infections, even cancer.

10 May 2022

Researchers explore the hemodynamics in vascular, atherosclerotic diseases

Medical interventions, such as improving diet, lowering blood lipids, or controlling blood pressure and blood sugar, can only do so much when it comes to treating atherosclerotic disease.

10 May 2022

Exploring simultaneous and sequential COVID-19 vaccine candidate

Researchers developed novel lipid nanoparticle (LNP)-based messenger ribonucleic acid vaccine formulations against three pathogenic coronaviruses.

10 May 2022

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

A new study has focused on the microcirculatory factors associated with neurological complications of COVID-19.

10 May 2022

Exploring low serum volume assays for SARS-CoV-2 antibodies

Researchers developed several non-commercial/in-house low serum volume assays for detecting and characterizing SARS-CoV-2 antibodies.

9 May 2022

Third BNT162b2 dose elicits more durable immune response than second dose

Researchers evaluated the durability of immune responses post-third dose of the BNT162b2 vaccine against SARS-CoV-2.

9 May 2022

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

Researchers developed a novel protocol to examine dopamine (DA) neurons extracted from Parkinson’s disease (PD) patients using single-cell genomic sequencing.

9 May 2022

miRNAs associated with varying clinical presentations of SARS-CoV-2

A recent article published in the journal iSCIENCE demonstrated different micro ribonucleic acids (miRNAs) linked with various presentations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.

5 May 2022

$Using AI to predict how cancer may affect the probability of spinal fractures$

Using AI to predict how cancer may affect the probability of spinal fractures

As medicine continues to embrace machine learning, a new study suggests how scientists may use artificial intelligence to predict how cancer may affect the probability of fractures along the spinal column.

5 May 2022

Efficacy of affinity resin containing Galanthus nivalis agglutinin against SARS-CoV-2

A new study demonstrated the efficacy of the Galanthus nivalis agglutinin (GNA)-incorporated affinity resin against various SARS-CoV-2 variants.

3 May 2022

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

Researchers developed a mucosal vaccine for COVID-19 based on bacteriophage.

3 May 2022

New smartphone-powered microchip opens the door for faster, cheaper at-home medical testing

A University of Minnesota Twin Cities research team has developed a new microfluidic chip for diagnosing diseases that uses a minimal number of components and can be powered wirelessly by a smartphone. The innovation opens the door for faster and more affordable at-home medical testing.

3 May 2022

New insights on the mechanisms of transmission of bacterial pathogen that causes listeriosis

Listeriosis is a zoonotic disease of food origin that can cause, both in the human species and in animals, symptoms of gastroenteritis, meningitis, bacteremia and miscarriages.

2 May 2022

Neutralizing antibodies produced following COVID-19 BNT162b2 vaccine found to activate complement cascade

Researchers investigated the complement component 1q (C1q) binding and subsequent complement activation by neutralizing antibodies (nAbs) produced following COVID-19 vaccination.

2 May 2022

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

A new study describes the development of new molecules with inhibitory activity against the SARS-CoV-2 viral main protease (Mpro) enzyme, based on rattlesnake venom.

29 Apr 2022

Children treated with antibiotics have abundant fungal microbiota in the gut, study reveals

A study recently completed at the University of Helsinki revealed that the fungal microbiota in the gut is more abundant and diverse in children treated with antibiotics compared with the control group even six weeks following the start of the antibiotic course.

29 Apr 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

Nanobody effectively neutralizes pseudotyped ancestral SARS-CoV-2 and Omicron spike proteins

Researchers identified a nanobody inhibiting SARS-CoV-2 variants.

26 Apr 2022

micro News and Research

Antifungal agent Bifonazole as an antiviral against SARS-CoV-2

Discovery of host co-factors necessary for SARS-CoV2 infection

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

Researchers explore the hemodynamics in vascular, atherosclerotic diseases

Exploring simultaneous and sequential COVID-19 vaccine candidate

Researchers report widespread prevalence of reactive and acute inflammatory CNS microvasculopathy in 36 COVID-19 brain autopsies

Exploring low serum volume assays for SARS-CoV-2 antibodies

Third BNT162b2 dose elicits more durable immune response than second dose

Single-cell genomic sequencing identifies a subpopulation of human dopamine neurons that degenerates in Parkinson’s disease

miRNAs associated with varying clinical presentations of SARS-CoV-2

Using AI to predict how cancer may affect the probability of spinal fractures

Efficacy of affinity resin containing Galanthus nivalis agglutinin against SARS-CoV-2

Needle- and adjuvant-free vaccination with non-infectious T4-COVID nanoparticles induces strong immunity in mice

New smartphone-powered microchip opens the door for faster, cheaper at-home medical testing

New insights on the mechanisms of transmission of bacterial pathogen that causes listeriosis

Neutralizing antibodies produced following COVID-19 BNT162b2 vaccine found to activate complement cascade

SARS-CoV-2 Mpro inhibitors built on rattlesnake venom scaffold

Children treated with antibiotics have abundant fungal microbiota in the gut, study reveals

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Nanobody effectively neutralizes pseudotyped ancestral SARS-CoV-2 and Omicron spike proteins

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