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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

New applications for high-throughput flow cytometry in drug discovery

A new special issue of SLAS Discovery reflects examples of the recent groundswell of creative new applications for high-throughput flow cytometry in drug discovery.

24 Jul 2018

UConn microbiologists find evidence for antibiotic resistance in leech's gut

Plastic surgery patients were getting infections with antibiotic resistant bacteria, and no one knew why. UConn microbiologists found the answer in a leech's gut. Their research, published today in mBio, provides proof that tiny levels of antibiotics found in the environment can encourage bacterial resistance.

24 Jul 2018

EPFL scientists develop new optical nanotube sensors using synthetic biology

EPFL scientists have developed new nanotube biosensors using synthetic biology, which improves their sensing capabilities in complex biofluids, such as blood and urine. The study is published in the Journal of Physical Chemistry Letters.

24 Jul 2018

Large-scale DNA sequence data on Alzheimer's disease to be made available to investigators

The National Institute on Aging Genetics of Alzheimer's Disease Data Storage Site will begin making large-scale DNA sequence data available to investigators.

24 Jul 2018

Scientists find abnormal gene copying in fruit fly models of tauopathies

It sounds like science fiction: Nefarious genes clone themselves and settle their rogue copies in distant outposts of the galaxy (namely, our DNA), causing disease.

24 Jul 2018

Mutated gene linked to 3-year-old girl's severe neurological symptoms

A young girl with severe neurological symptoms finally has a diagnosis, following the discovery by the Translational Genomics Research Institute of a genetic mutation that likely caused the girl to experience a cascade of symptoms.

24 Jul 2018

Mysterious molecule Yin Yang may fuel tumor growth in breast cancer

Scientists have unveiled clues about a mysterious molecule called Yin Yang1 - and revealed it may fuel tumor growth in breast cancer.

23 Jul 2018

Imaging study shows how junk DNA activates genes

Researchers at Princeton University have used video imaging to capture the process by which junk DNA activates genes.

23 Jul 2018

Restoring mitochondrial function to reverse aging-related skin wrinkles, hair loss in mice

Wrinkled skin and hair loss are hallmarks of aging. What if they could be reversed?

20 Jul 2018

Karius Test accurately detects invasive fungal infections, shows study

Karius, a life sciences company transforming infectious disease diagnostics with genomics and data through the innovative use of next-generation sequencing to analyze microbial cell-free DNA, announced today the positive results of a clinical study using blood samples from patients with confirmed invasive fungal infections.

20 Jul 2018

Yeast species used in biotechnology, food industries causes drug-resistant yeast infections

A major cause of drug-resistant clinical yeast infections is the same species previously regarded as non-pathogenic and commonly used in the biotechnology and food industries.

20 Jul 2018

New breeding technologies could enhance shape, size, color, and health benefits of produce

Forget vegetables with dull colors and fuzzy skin or fruits that lack of flavor--the produce aisle of the future could offer plant products that are designed for creative cooks and fussy eaters.

20 Jul 2018

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair of scissors, in their case with the goal of cutting strands of infecting DNA.

20 Jul 2018

Genetic sequencing reveals new clues to aggressiveness of prostate cancer

Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.

20 Jul 2018

Genome research suggests presence of enteric fever in medieval Europe

Genome research conducted by the University of Warwick suggests that enteric fever, a potentially lethal disease more commonly found in hot countries, was present in medieval Europe.

20 Jul 2018

Researchers raise viability of cloned mice using somatic cell nuclear transfer method

An international group of researchers have raised the viability of mice that were cloned using a method called somatic cell nuclear transfer, by stimulating two epigenetic factors, and by doing this have shown that creating cloned animals more efficiently will require further work in the area of epigenetics.

20 Jul 2018