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Changes in Troponin I protein can lead to cardiac muscle malfunction and precipitate heart failure

A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.

13 Sep 2012

Popular Science magazine names University of Minnesota chemist among ‘Brilliant 10’

University of Minnesota chemist Christy Haynes has been named one of Popular Science magazine's "Brilliant 10," an honor that recognizes an elite group of young scientists whose research is expected to dramatically impact their fields. Haynes' profile was published today on the PopSci website and is featured in the Popular Science magazine now on newsstands.

12 Sep 2012

APS conference to explore potential mechanisms behind health benefits of exercise

The effects of physical inactivity are, literally, hazardous to your health. Although the detrimental effects of being inactive are generally thought to be associated with childhood obesity and Type 2 diabetes, they have a significant impact on other illnesses. Physical inactivity contributed at least 25 percent to the prevalence of hip fractures, osteoporosis, coronary heart disease, and colon cancer according to recent data released by the U.S. Department of Health and Human Services.

12 Sep 2012

Latinos more likely to store fat in the pancreas and develop type 2 diabetes

Latinos are more likely to store fat in the pancreas and are less able to compensate by excreting additional insulin, a Cedars-Sinai study shows.

12 Sep 2012

Instrument-assisted spinal manipulation shows hypoalgesic effects

Instrument-assisted spinal manipulative therapy targeted to the low-back region has an immediate and widespread hypoalgesic effect, say researchers.

11 Sep 2012

Stanford and MBL scientists win prestigious Lasker Awards

Scientists who invented new ways to study how "cargo" is moved within cells and, as a result, discovered a new biological motor protein, kinesin, at the Marine Biological Laboratory (MBL) in Woods Hole, Mass., have received the prestigious 2012 Lasker Award for Basic Medical Research, the Albert and Mary Lasker Foundation announced today.

11 Sep 2012

MicroRNA-145 gene therapy can drastically reduce severity and progression of atherosclerosis

Researchers at St. Michael's Hospital are one step closer to understanding why plaque bursts in coronary arteries and causes heart attacks.

11 Sep 2012

Cardiac stem cells from newborns show stronger regenerative ability

Researchers at the University of Maryland School of Medicine, who are exploring novel ways to treat serious heart problems in children, have conducted the first direct comparison of the regenerative abilities of neonatal and adult-derived human cardiac stem cells.

11 Sep 2012

Automated system for mapping protein-DNA interactions

Since the sequencing of the human genome in 2001, all our genes - around 20,000 in total - have been identified. But much is still unknown - for instance where and when each is active. Next to each gene sits a short DNA segment, and the activity of this regulatory segment determines whether the gene will be turned on, where and how strongly.

10 Sep 2012

Novel surgical technique removes invasive facial tumor, recreates functional lower jaw and mouth

Using a novel surgical approach, it's possible to rebuild a functional lower jaw and mouth, and preserve a patient's ability to eat and speak after removing an invasive facial tumor, according to a new report from Henry Ford Hospital in Detroit.

10 Sep 2012

Insight into how tissue stiffness drives cancer

The stiffness of breast tissue is increasingly recognized as an important factor explaining the onset of breast cancer. Stiffening induces molecular changes that promote cancerous behavior in cells. Bioengineering studies have found that breast cancer cells grown on a 3-D gel have enhanced cell replication and decreased organization as rigidity increases.

10 Sep 2012

Cedars-Sinai receives CIRM grant to continue study of stem cell therapy for heart disease

A team of Cedars-Sinai Heart Institute stem cell researchers today was awarded a $1.3 million grant from the California Institute of Regenerative Medicine to continue study of an experimental stem cell therapy that treats heart attack patients with heart-derived cells. Earlier this year, data from the first clinical trial of the stem cell treatment showed the therapy helped damaged hearts regrow healthy muscle.

10 Sep 2012

CIRM awards Cedars-Sinai $1.3M to study stem cell therapy for heart attacks

7 Sep 2012

New findings establish connection between microRNAs and cellular metabolism

New findings establish a connection between microRNAs and cellular metabolism, suggesting that a drug designed to inhibit these tiny molecules -- once considered to be "junk" DNA -- would have a positive effect against obesity.

7 Sep 2012

Harvard experts create biocompatible hydrogel

A team of experts in mechanics, materials science, and tissue engineering at Harvard have created an extremely stretchy and tough gel that may pave the way to replacing damaged cartilage in human joints.

6 Sep 2012

Preliminary research findings from Kessler Foundation’s Ekso device study on SCI

Kessler Foundation has released preliminary research findings from its clinical study of the wearable robotic exoskeletal device, Ekso. Gail Forrest, PhD, assistant director of Human Performance and Engineering Research, presented the Ekso research data on September 3, at the meeting of the Academy of Spinal Cord Injury Professionals at the Rio Suites in Las Vegas. Dr. Forrest directs mobility research at the Foundation, including activity-based locomotor therapy, functional electrical stimulation, and treadmill training with the LokomatPro v6, as well as Ekso.

6 Sep 2012

Scripps Florida designs new compound that shows promise against tremor ataxia syndrome

Scientists on the Florida campus of The Scripps Research Institute have designed a compound that shows promise as a potential therapy for one of the diseases closely linked to fragile X syndrome, a genetic condition that causes mental retardation, infertility, and memory impairment, and is the only known single-gene cause of autism.

6 Sep 2012

Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus

Rigel Pharmaceuticals, Inc. today announced that it has commenced Phase 2 clinical studies with two of the company's most advanced proprietary therapeutic product candidates. R343 is an inhaled SYK inhibitor that is being evaluated as a potential treatment for allergic asthma.

6 Sep 2012

People with generalized anxiety disorder have weak brain connections

A new University of Wisconsin-Madison imaging study shows the brains of people with generalized anxiety disorder (GAD) have weaker connections between a brain structure that controls emotional response and the amygdala, which suggests the brain's "panic button" may stay on due to lack of regulation.

5 Sep 2012

A-kinase anchoring proteins influence levels of glucose in the body

Scientists from the United States and Sweden have discovered a new control point that could be important as a drug target for the treatment of diabetes and other metabolic diseases.

4 Sep 2012

Muscle News and Research

Changes in Troponin I protein can lead to cardiac muscle malfunction and precipitate heart failure

Popular Science magazine names University of Minnesota chemist among ‘Brilliant 10’

APS conference to explore potential mechanisms behind health benefits of exercise

Latinos more likely to store fat in the pancreas and develop type 2 diabetes

Instrument-assisted spinal manipulation shows hypoalgesic effects

Stanford and MBL scientists win prestigious Lasker Awards

MicroRNA-145 gene therapy can drastically reduce severity and progression of atherosclerosis

Cardiac stem cells from newborns show stronger regenerative ability

Automated system for mapping protein-DNA interactions

Novel surgical technique removes invasive facial tumor, recreates functional lower jaw and mouth

Insight into how tissue stiffness drives cancer

Cedars-Sinai receives CIRM grant to continue study of stem cell therapy for heart disease

CIRM awards Cedars-Sinai $1.3M to study stem cell therapy for heart attacks

New findings establish connection between microRNAs and cellular metabolism

Harvard experts create biocompatible hydrogel

Preliminary research findings from Kessler Foundation’s Ekso device study on SCI

Scripps Florida designs new compound that shows promise against tremor ataxia syndrome

Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus

People with generalized anxiety disorder have weak brain connections

A-kinase anchoring proteins influence levels of glucose in the body

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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