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Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

A team of researchers led by a biomedical scientist at the University of California, Riverside, has identified a novel mechanism by which loss-of-function mutations in the gene PTPN2, found in many patients with inflammatory bowel disease, or IBD, affect how intestinal epithelial cells maintain a barrier.

3 Sep 2021

Precursor to ulcerative colitis exists several years before disease onset, study shows

After the first symptoms, the diagnosis of the bowel disease ulcerative colitis may take a few months. As shown in a study at örebro University, there is, however, a precursor to the disease already several years before its onset.

3 Sep 2021

Telemedicine abortions offer cheaper options but may also undermine critical clinics

Allison Hansen had just gone through a breakup with her boyfriend last year when she discovered she was pregnant. She already had an 8-year-old son and did not want another child.

3 Sep 2021

Stem-like T cells within certain lymph nodes could be natural cancer fighters, study shows

In a new study by Yale Cancer Center, researchers show stem-like T cells within certain lymph nodes could be natural cancer fighters.

3 Sep 2021

Researchers assess robotic and navigation assisted pedicle screw placement in degenerative spinal surgery

The use of robotics and computer navigation in spinal surgery is rapidly expanding. Increasing numbers of hospitals and spine surgeons are adopting the technology, which aims to enhance precision, accuracy and predictability, according to Darren R. Lebl, MD, MBA, a spine surgeon at Hospital for Special Surgery.

2 Sep 2021

Study establishes a new resource for exploring and understanding Alzheimer's disease

A study led by researchers from Brigham and Women's Hospital has established a new resource for exploring and understanding Alzheimer's disease (AD) on an individualized level.

2 Sep 2021

UTSA receives $3.2 million CPRIT grant for developing new approach to fight against cancer

The University of Texas at San Antonio has been awarded a five-year $3.2 million grant from the Cancer Prevention & Research Institute of Texas.

2 Sep 2021

UCD spin-out company secures €595k in seed funding to advance drug development

BioSimulytics (www.biosimulytics.ai), a University College Dublin (UCD) spin-out company, today announced that it has secured €595k in initial seed funding from a number of strategic angel investors and Enterprise Ireland.

2 Sep 2021

Link discovered between brain’s opioid system and food craving triggered by external stimuli

Brain regulation of feeding behavior traits has remained incompletely understood. In their latest study, researchers at the Turku PET Centre, Finland, discovered a connection between the function of the opioid system and food craving triggered by appetitive external stimuli.

2 Sep 2021

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

New research has uncovered a precision medicine test using blood proteins to identify a novel patient subgroup of idiopathic multicentric Castleman disease (iMCD), a rare blood disorder, who are more likely to respond to siltuximab, the only FDA approved treatment for the disease.

2 Sep 2021

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Immunotherapy is very effective for many cancers, but the treatment can also cause autoimmune side effects. Encephalitis is one of the most serious and difficult-to-diagnose side effects of immunotherapy.

2 Sep 2021

Study could help physicians better manage patients experiencing debilitating stiffness after revision TKA

A new study by researchers at Hospital for Special Surgery in New York City presented today at the American Academy of Orthopaedic Surgeons 2021 annual meeting could help physicians better manage patients who experience debilitating stiffness after they undergo knee replacement surgery.

2 Sep 2021

Simple blood test could determine the right drug, dosage for patients with rheumatoid arthritis

A simple blood test could determine which drug and dosage is more likely to be effective against rheumatoid arthritis, potentially saving sufferers serious side effects and Australian taxpayers millions of dollars.

2 Sep 2021

Study paves the way for developing new treatments to fight gonorrhea superbug

Sexually transmitted infection gonorrhea is on the rise as a major public health burden worldwide, with around 87 million new infections a year largely caused by the superbug Neisseria gonorrhoeae which experts fear will soon be untreatable.

2 Sep 2021

Research investigates how drug-eluting stent affects arterial tissue permeability and blood flow

For patients with symptomatic coronary artery disease, the best course of action often involves implanting a drug-eluting stent into the artery where a plaque buildup is blocking blood flow to the heart.

2 Sep 2021

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

Sepsis is the leading cause of death in Brazil's intensive care units (ICUs). Among patients who progress to the severe form of the disease, 40% die, and the survivors often suffer from cardiovascular and neurological complications, as well as a significant decline in immunity lasting for years after they are discharged from hospital.

2 Sep 2021

UC cosmetic scientist receives grant to explore skin permeation of chemical agents

A researcher at the University of Cincinnati is looking at ways to make products such as anti-aging and skin lightening creams, lotions, and gels more effective.

2 Sep 2021

Review: Remission should be the primary treatment goal of GPs for people with type 2 diabetes

Achieving 'remission' for people with type 2 diabetes through dietary approaches and weight loss should be the primary treatment goal of GPs and healthcare practitioners, concludes a large-scale review of clinical evidence led by researchers at UCL and Aston University.

2 Sep 2021

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week in The Lancet Respiratory Medicine.

1 Sep 2021

Researchers find new reward circuitry beyond dopamine

The key to overcoming addictions and psychiatric disorders lives deep inside the netherworld of our brains and the circuitry that causes us to feel good.

1 Sep 2021

Drugs News and Research

Scientists identify novel mechanism that links genetic defect in IBD patients to gut leakiness

Precursor to ulcerative colitis exists several years before disease onset, study shows

Telemedicine abortions offer cheaper options but may also undermine critical clinics

Stem-like T cells within certain lymph nodes could be natural cancer fighters, study shows

Researchers assess robotic and navigation assisted pedicle screw placement in degenerative spinal surgery

Study establishes a new resource for exploring and understanding Alzheimer's disease

UTSA receives $3.2 million CPRIT grant for developing new approach to fight against cancer

UCD spin-out company secures €595k in seed funding to advance drug development

Link discovered between brain’s opioid system and food craving triggered by external stimuli

Research uncovers test to identify iMCD patients with superior response to FDA-approved treatment

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Study could help physicians better manage patients experiencing debilitating stiffness after revision TKA

Simple blood test could determine the right drug, dosage for patients with rheumatoid arthritis

Study paves the way for developing new treatments to fight gonorrhea superbug

Research investigates how drug-eluting stent affects arterial tissue permeability and blood flow

Newly discovered cell type makes survivors of sepsis more vulnerable to infections

UC cosmetic scientist receives grant to explore skin permeation of chemical agents

Review: Remission should be the primary treatment goal of GPs for people with type 2 diabetes

Rheumatoid arthritis drug plus standard of care may reduce COVID-19 mortality for hospitalized patients

Researchers find new reward circuitry beyond dopamine

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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