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Lettuce could protect astronauts from bone density loss in microgravity

Astronauts might one day grow and eat genetically modified plants to ward off disease associated with long spaceflights. Researchers at the University of California, Davis College of Engineering have developed a transgenic, or genetically modified, lettuce producing a drug to protect against bone density loss in microgravity.

22 Mar 2022

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

A human immune system is a lot like the board game Mouse Trap: it's a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub - which, in turn, springs a trap on some plastic mice - proteins trigger other proteins to activate immune cells and direct them toward germs.

22 Mar 2022

Vaccine-induced antibody response to SARS-CoV-2 Omicron variant in patients with B cell malignancies with and without active B cell-targeted therapy

Researchers have determined the effect of booster immunization on the levels of antibodies generated, against SARS-CoV-2 variants, including the Omicron strain, in cancer patients with or without active B cell-targeted therapy.

22 Mar 2022

Researchers identify a protein that protects against breast cancer growth

Researchers at Karolinska Institutet in Sweden have identified a protein that protects against breast tumor growth and that can be linked to a better prognosis in breast cancer patients.

22 Mar 2022

Maternal and infant antibody levels and transplacental transfer following SARS-CoV-2 infection and vaccination

A recent study evaluated maternal antibody responses against SARS-CoV-2 and transplacental transfer.

22 Mar 2022

SARS-CoV-2 nanobody that binds to the receptor-binding domain could prevent COVID-19 in animals

A new study assessed the potential of a nanobody – directly prepared by binding to SARS-CoV-2 spike receptor-binding domain protein, in the treatment of COVID-19.

22 Mar 2022

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Researchers presented a systematic analysis of the affinity and conformational dynamics between the binding of SARS-CoV-2 receptor-binding domain spike protein and the host angiotensin-converting enzyme 2 receptor.

22 Mar 2022

Predatory bacterium can sculpt its own shape to fit inside the prey

Scientists have found that a predatory bacterium, capable of invading and consuming harmful bugs such as E.coli and Salmonella, can sculpt its own shape to fit inside its prey.

22 Mar 2022

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Researchers performed an in situ analysis to evaluate the correlation between CD48 expression and COVID-19.

22 Mar 2022

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Researchers evaluated the importance of the Ex3Lx6L motif in SARS-CoV-2 entry into host cells mediated by the spike protein syncytium formation and membrane fusion.

22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

Waning antibody responses in SARS-CoV-2-infected or vaccinated population

A recent study posted to the bioRxiv* preprint server evaluated the effects of the waning of antibodies after coronavirus disease 2019 (COVID-19) infection or vaccination.

22 Mar 2022

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

A recent study posted to the bioRxiv* preprint server demonstrated the neutralizing capacity of existing SARS-CoV-2 vaccines against the severe acute respiratory coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineages.

22 Mar 2022

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

In a recent study posted to the bioRxiv* preprint server, researchers conducted a phylogenetic investigation of the human parainfluenza type 3 virus strain (HPIV3) that caused an outbreak in South Korea amid the coronavirus disease 2019 (COVID-19) pandemic.

22 Mar 2022

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

The findings of a new study suggest that a ketogenic diet - which is low in carbohydrates and protein, but high in fat - helps to kill pancreatic cancer cells when combined with a triple-drug therapy developed by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

22 Mar 2022

New research proves benefit of vaccination after recovery from COVID-19

When our immune system comes into contact with the SARS-CoV-2 coronavirus, it fights back and produces antibodies.

22 Mar 2022

Association between seropositivity and comorbidities after COVID-19 vaccination

In a recent study posted to the medRxiv* preprint server, researchers demonstrated that comorbidities attenuated the chance of seropositivity following coronavirus disease 2019 (COVID-19) vaccination.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

Novel screening platform flags 95% of stage 1 cancers

A novel screening platform has flagged more than 95 percent of stage 1 cancers, according to a pilot study published in Nature Communications Medicine. If validated by future studies, the approach offers a new way to detect the third-leading cause of U.S. cancer deaths in 2020.

21 Mar 2022

Protein C News and Research

Lettuce could protect astronauts from bone density loss in microgravity

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

Vaccine-induced antibody response to SARS-CoV-2 Omicron variant in patients with B cell malignancies with and without active B cell-targeted therapy

Researchers identify a protein that protects against breast cancer growth

Maternal and infant antibody levels and transplacental transfer following SARS-CoV-2 infection and vaccination

SARS-CoV-2 nanobody that binds to the receptor-binding domain could prevent COVID-19 in animals

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Predatory bacterium can sculpt its own shape to fit inside the prey

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Posaconazole found to be effective as a small molecule fusion inhibitor against SARS-CoV-2 variants

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Waning antibody responses in SARS-CoV-2-infected or vaccinated population

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

New research proves benefit of vaccination after recovery from COVID-19

Association between seropositivity and comorbidities after COVID-19 vaccination

Is COVID-19 on the verge of ending?

Novel screening platform flags 95% of stage 1 cancers

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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