Psychiatry News and Research

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Psychiatry is the treatment, study and prevention of mental disorders.

Five common genetic variations linked to metabolic syndrome and HDL cholesterol levels

Nutrition researchers at Washington University School of Medicine in St. Louis have identified five common genetic variations that increase the risk of metabolic syndrome, a group of factors linked to heart disease and diabetes. Another variant they found appeared to protect against the condition.

17 Jun 2008

Alcohol and drug misuse fuels Scottish suicide and homicide rates

Alcohol and drug misuse mean Scots are almost twice as likely to kill or take their own life compared to people living in England and Wales, research published Monday, June 16 reveals.

From The University of Manchester 16 Jun 2008

Antipsychotic drugs get FDA label changes

The U.S. Food and Drug Administration today exercised its new authority under the Food and Drug Administration Amendments Act of 2007 (FDAAA) to require manufacturers of "conventional" antipsychotic drugs to make safety-related changes to prescribing information, or labeling, to warn about an increased risk of death associated with the off-label use of these drugs to treat behavioral problems in older people with dementia.

16 Jun 2008

UT Southwestern investigators test groundbreaking depression research in real-world setting

UT Southwestern Medical Center psychiatry researchers have taken what they learned from their groundbreaking research on treating depression and are applying it to real-world clinical settings.

15 Jun 2008

"HiCy" drug regimen reverses multiple sclerosis symptoms in selected patients

A short-term, very-high dose regimen of the immune-suppressing drug cyclophosphamide seems to slow progression of multiple sclerosis (MS) in most of a small group of patients studied and may even restore neurological function lost to the disease, Johns Hopkins researchers report. The findings in nine people, most of whom had failed all other treatments, suggest new ways to treat a disease that tends to progress relentlessly.

10 Jun 2008

Genetic variation linked to earlier onset of Alzheimer's symptoms

Investigators at Washington University School of Medicine in St. Louis have identified a genetic variation associated with an earlier age of onset in Alzheimer's disease.

9 Jun 2008

Drug used to treat alcohol dependence also works for pathological gamblers

Scientists in the U.S. have found that a drug commonly prescribed for the treatment of alcoholism and drug dependence, also works for pathological gamblers.

8 Jun 2008

Cancer patients report less fatigue while taking narcolepsy drug

A large, phase III clinical study showed the drug modafinil (Provigil) alleviated severe cancer-related fatigue for many patients, paving the way for the first reliable treatment for this debilitating and common side effect.

5 Jun 2008

Nearly one in five teenagers admit eating problems, but anxiety is a bigger problem than appearance

Eighteen per cent of school children who took part in two health surveys carried out a year apart admitted they had eating problems, according to research published in the latest Journal of Advanced Nursing.

4 Jun 2008

How and where fat is stored predicts disease risk better than weight

Young adults who abuse amphetamines may be at greater risk of suffering a heart attack, UT Southwestern Medical Center researchers have found.

3 Jun 2008

Long term dope use shrinks the brain

According to Australian researchers the long term use of marijuana may cause parts of the brain which control memory, emotion and aggression, to shrink.

3 Jun 2008

Exposure-based therapy may help prevent post-traumatic stress disorder

Exposure-based therapy, in which recent trauma survivors are instructed to relive the troubling event, may be effective in preventing the progression from acute stress disorder to post-traumatic stress disorder, according to a report in the June issue of Archives of General Psychiatry.

2 Jun 2008

Long-term, heavy cannabis use may shrink brain's hippocampus and amygdala

Long-term, heavy cannabis use may be associated with structural abnormalities in areas of the brain known as the hippocampus and amygdala, according to a report in the June issue of Archives of General Psychiatry.

2 Jun 2008

Bipolar disorder in adolescents is a huge risk factor for smoking and substance abuse

A study from the Massachusetts General Hospital (MGH) supports previous reports that adolescents with bipolar disorder are at increased risk for smoking and substance abuse.

2 Jun 2008

Distinct clusters of genetic markers linked to treatment responses for smoking cessation

Scientists have identified distinct clusters of genetic markers associated with the likelihood of success or failure of two smoking cessation treatments, nicotine replacement therapy (NRT) and the medication bupropion (Zyban). This study, supported by the National Institute on Drug Abuse (NIDA) and the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), was published in the June issue of the journal Archives of General Psychiatry.

2 Jun 2008

Researchers pinpoint gene mutations responsible for 10 percent of non-familial cases of schizophrenia

Scans of the genome of patients with schizophrenia have revealed rare spontaneous copy number mutations that account for at least 10 percent of the non-familial cases of the disease.

1 Jun 2008

University of Bristol to test effectiveness of cognitive behavioural therapy

A team of researchers, led by Dr Nicola Wiles at the University of Bristol, has been awarded £1.2 million by the National Institute for Health Research Health Technology Assessment (NIHR HTA) programme for a clinical trial to investigate the effectiveness of cognitive behavioural therapy (CBT) for patients with depression who do not respond to treatment with antidepressants.

30 May 2008

Avoiding spleen removal for Cooley's anemia sufferers

Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100,000 African-Americans. The World Health Organization estimates that between 50,000-100,000 children are born with the disease each year.

27 May 2008

Molecular fingerprint of cocaine addiction revealed

The first large-scale analysis of proteins in the brains of monkeys addicted to cocaine reveals new information on how long-term cocaine use changes the amount and activity of various proteins affecting brain function.

27 May 2008

Gene mutations in mice mimic human-like sleep disorder

Mutations in two genes that control electrical excitability in a portion of the brain involved in sleep create a human-like insomnia disorder in mice, UT Southwestern Medical Center researchers have found. The findings may help scientists better understand the disorder and provide an animal model for developing treatments.

20 May 2008