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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Study shows hsa-miR-146a overexpressed in most metastatic tumors

In order to kill, bladder cancer must metastasize, most commonly to the lung - what are the differences between bladder cancers that do and do not make this deadly transition? Research presented by the Director of the University of Colorado Cancer Center at the AACR Annual Meeting 2013 shows that one big difference is a little molecule known as hsa-miR-146a.

11 Apr 2013

Study: microRNA is designed to stop proliferation of prostate cancer cells

The most recent in a series of studies from a team at the UC Davis Comprehensive Cancer Center has shown that a single molecule is at the heart of one of the most basic survival tactics of prostate cancer cells.

10 Apr 2013

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

A dozen Ludwig scientists from around the world presented the latest advancements in basic and clinical cancer research at this week’s American Association for Cancer Research (AACR) Annual Meeting 2013. Progress in immunotherapy and epigenetics led the program with important diagnostic and treatment implications for emerging cancer therapy.

10 Apr 2013

Tiny proteins prevent bacterial gene transcription

In the search for new antibiotics, researchers are taking an unusual approach: They are developing peptides, short chains of protein building blocks that effectively inhibit a key enzyme of bacterial metabolism.

10 Apr 2013

UCSB researchers examine role played by Rhs proteins in bacterial intercellular competition

There's an epic battle taking place that's not on the national radar: intercellular competition. While it's not an Olympic event, new research from UC Santa Barbara demonstrates that this microscopic rivalry can be just as fierce as humans going for the gold.

9 Apr 2013

Study shows genetics could play a role in exercise motivation

Studies show 97 percent of American adults get less than 30 minutes of exercise a day, which is the minimum recommended amount based on federal guidelines. New research from the University of Missouri suggests certain genetic traits may predispose people to being more or less motivated to exercise and remain active.

9 Apr 2013

Relationship between obesity and PCOS may be exaggerated, say researchers

The relationship between obesity and polycystic ovary syndrome may be exaggerated, likely because the women who actively seek care for the condition tend to be heavier than those identified through screening of the general population, researchers report.

9 Apr 2013

Exosome profiling of mRNAs and miRNAs in serum samples presented at AACR meeting

Exosome Diagnostics, a leading developer of biofluid-based molecular diagnostics for use in personalized medicine, today announced that the company is presenting a late-breaking abstract at the AACR Annual Meeting 2013, in Washington D.C.

9 Apr 2013

Three researchers receive 2013 Wiley Prize in Biomedical Sciences

Deborah E. Wiley, Chair of The Wiley Foundation, John Wiley & Sons, Inc. (NYSE: JWa & JWb) today awarded the 2013 Wiley Prize in Biomedical Sciences to Dr. Michael Young, Rockefeller University, Dr. Jeffrey Hall, Brandeis University (Emeritus), and Dr. Michael Rosbash, Brandeis University.

9 Apr 2013

Vertex to conduct two Phase 2 studies of VX-135 in combination with daclatasvir

Vertex Pharmaceuticals Incorporated today announced it has entered into a non-exclusive agreement with Bristol-Myers Squibb Company to conduct Phase 2 studies of once-daily all-oral treatment regimens containing Vertex's nucleotide analogue hepatitis C virus polymerase inhibitor VX-135 and Bristol-Myers Squibb's NS5A replication complex inhibitor daclatasvir for the treatment of hepatitis C.

6 Apr 2013

Overexpression of miR-155 promotes growth of blood vessels in tumors and metastasis

Researchers at Moffitt Cancer Center have determined that the overexpression of microRNA-155 (miR-155), a short, single strand of ribonucleic acid encoded by the miR-155 host gene, promotes the growth of blood vessels in tumors, tumor inflammation, and metastasis.

4 Apr 2013

Illumina releases TruSight Tumor for NGS-based somatic variant detection in solid tumors

Illumina, Inc. today announced the next product in its TruSight line of content sets, TruSight Tumor, for NGS-based somatic variant detection in solid tumors.

From Illumina, Inc. 4 Apr 2013

Clinical trial signals new era in treatment of neurodegererative disorders

The initial clinical trial of a novel approach to treating amyotrophic lateral sclerosis - blocking production of a mutant protein that causes an inherited form of the progressive neurodegererative disease - may be a first step towards a new era in the treatment of such disorders.

4 Apr 2013

TGen to present scientific benefits of whole genome sequencing at myeloma workshop

The scientific benefits of whole genome sequencing at the Translational Genomics Research Institute will be presented at the 14th International Myeloma Workshop, April 3-7 at the Kyoto International Conference Center.

4 Apr 2013

Inovio Pharmaceuticals reports release of phase II clinical trial results of ChronVac-C

Inovio Pharmaceuticals, Inc. today announced the release of preliminary clinical trial results by its collaborator ChronTech AS of their open label phase II clinical study of ChronVac-C, ChronTech's vaccine to treat hepatitis C virus infection.

2 Apr 2013

Neurological researchers discover novel approach for treatment of brain tumor

In a first-of-its-kind experiment using microvesicles generated from mesenchymal bone marrow cells (MSCs) to treat cancer, neurological researchers at Henry Ford Hospital have discovered a novel approach for treatment of tumor.

2 Apr 2013

Exosomes can transfer membrane proteins, study reveals

Important new research from UMass Medical School demonstrates how exosomes shuttle proteins from neurons to muscle cells where they take part in critical signaling mechanisms, an exciting discovery that means these tiny vehicles could one day be loaded with therapeutic agents, such as RNA interference, and directly target disease-carrying cells.

28 Mar 2013

CureVac begins CV9104 Phase 2b clinical trial in patients with castration-resistant prostate cancer

CureVac GmbH, a clinical stage biopharmaceutical company that has pioneered the development of a new class of therapies and vaccines based on messenger RNA, today announced that it has initiated a double-blind, randomized Phase 2b clinical trial of its RNActive cancer vaccine, CV9104, for the treatment of patients with castration-resistant prostate cancer.

28 Mar 2013

Trovagene introduces urine-based HPV-HR DNA test for identifying high-risk HPV strains

Trovagene, Inc., today announced the commercial availability of its urine-based HPV-HR (high-risk) assay, a molecular human papillomavirus test.

27 Mar 2013

Two studies shed light on molecular biology of three blood disorders

Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.

26 Mar 2013

RNA News and Research

Further Reading

Study shows hsa-miR-146a overexpressed in most metastatic tumors

Study: microRNA is designed to stop proliferation of prostate cancer cells

Immunotherapy and epigenetics advancements presented by Ludwig at the American Association for Cancer Research

Tiny proteins prevent bacterial gene transcription

UCSB researchers examine role played by Rhs proteins in bacterial intercellular competition

Study shows genetics could play a role in exercise motivation

Relationship between obesity and PCOS may be exaggerated, say researchers

Exosome profiling of mRNAs and miRNAs in serum samples presented at AACR meeting

Three researchers receive 2013 Wiley Prize in Biomedical Sciences

Vertex to conduct two Phase 2 studies of VX-135 in combination with daclatasvir

Overexpression of miR-155 promotes growth of blood vessels in tumors and metastasis

Illumina releases TruSight Tumor for NGS-based somatic variant detection in solid tumors

Clinical trial signals new era in treatment of neurodegererative disorders

TGen to present scientific benefits of whole genome sequencing at myeloma workshop

Inovio Pharmaceuticals reports release of phase II clinical trial results of ChronVac-C

Neurological researchers discover novel approach for treatment of brain tumor

Exosomes can transfer membrane proteins, study reveals

CureVac begins CV9104 Phase 2b clinical trial in patients with castration-resistant prostate cancer

Trovagene introduces urine-based HPV-HR DNA test for identifying high-risk HPV strains

Two studies shed light on molecular biology of three blood disorders

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