Immune System News and Research

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Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

Researchers create new compound that appears to activate cancer-fighting T cells

Invariant natural killer T (iNKT) cells are powerful weapons our body's immune systems count on to fight infection and combat diseases like cancer, multiple sclerosis, and lupus. Finding ways to spark these potent cells into action could lead to more effective cancer treatments and vaccines.

2 Apr 2018

Researchers unravel immunopathogenesis of Johne's disease

A research team has unraveled the immunopathogenesis of Johne's disease, a chronic bovine disease that has caused endemics in Japan and many other countries, placing financial burdens on cattle farmers.

2 Apr 2018

Monash scientists discover how gonorrhea-causing superbug evades the immune system

Every year, more than 100 million people worldwide develop the sexually transmitted disease gonorrhea, with health consequences such as infertility, transmission of the disease to newborn babies, and increased risk of HIV infections. There has been a 63 percent rise in gonorrhea in Australia over the past five years.

30 Mar 2018

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

The U.S. Food and Drug Administration granted accelerated approval to Blincyto (blinatumomab) to treat adults and children with B-cell precursor acute lymphoblastic leukemia (ALL) who are in remission but still have minimal residual disease (MRD).

30 Mar 2018

Phase I clinical trial of HIV vaccines to begin in the U.S.

A Phase I clinical trial testing the safety of vaccines that might have the potential to prevent HIV infection will begin this month at four sites in the United States, marking the latest step in a three-decade quest at UMass Medical School to harness the power of DNA vaccines in addressing a major global health threat.

28 Mar 2018

New test detects Zika antibodies with high specificity

A test that detects antibodies against Zika virus in samples of blood serum with high specificity - and hence a low risk of cross-reaction with related microorganisms such as dengue virus - is set to come on to the Brazilian market before 2018 is out.

28 Mar 2018

New 'nanotweezers' could pave way for innovations in health monitoring and mobile technology

It's difficult to conceptualize a world where humans could casually manipulate nanoscale objects at will or even control their own biological matter at a cellular level with light.

27 Mar 2018

Antibiotic use linked to higher risk of severe viral disease in mice

People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show no signs of infection at all. One reason for the different outcomes may lie in the community of microbes that populate their intestinal tracts.

27 Mar 2018

New analysis describes how childhood obesity 'pandemic' promotes cancer

A Case Western Reserve University School of Medicine researcher has compiled evidence from more than 100 publications to show how obesity increases risk of 13 different cancers in young adults.

26 Mar 2018

Two immunotherapies used together for the first time to fight against solid tumors

Two immunotherapies - one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response - are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

26 Mar 2018

Specific immune cells may help slow progression of ALS, research shows

New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the disease, an important step towards developing new therapies to treat patients.

22 Mar 2018

Researchers propose alternative treatment to target lymphoma signaling at its root

Non-Hodgkin lymphomas are cancers that affect white blood cells of the immune system called B-lymphocytes or B cells. Like cells in all cancers, the B cells begin to grow out of control, creating tumors in the lymph nodes, spleen or other tissues. In 2010 alone, it was estimated that non-Hodgkin lymphomas caused 210,000 deaths worldwide.

22 Mar 2018

Researchers prove link between common childhood cancer and inflammation

The team of María Domínguez, researcher for the Neuroscience Institute, joint venture of the Miguel Hernández University in Elche and the Spanish National Research Council, has managed to prove for the first time that an important factor in the development of acute pediatric lymphoblastic leukemia is inflammation.

22 Mar 2018

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Neem Biotech, a Wales-based R&D biotech working in the field of novel antimicrobial drug development, announced today that it will be presenting results of its ongoing development work into the impact of NX-AS-401, its lead candidate,on biofilms in chronic cystic fibrosis lung infections at the 15th European Cystic Fibrosis Basic Science Conference taking place from 21st to 24th March 2018 in LoutrakiKorinthias, Greece.

From Neem Biotech 22 Mar 2018

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Treating people with advanced metastatic kidney cancer using a combination of the immunotherapy drugs nivolumab (Opdivo) and ipilimumab (Yervoy) significantly increased overall survival versus treatment with sunitinib (Sutent) alone, according to new findings from researchers at Memorial Sloan Kettering Cancer Center that were reported today in the New England Journal of Medicine.

22 Mar 2018

Immune cells can repopulate in the retina after elimination, mice study shows

Immune cells called microglia can completely repopulate themselves in the retina after being nearly eliminated, according to a new study in mice from scientists at the National Eye Institute.

21 Mar 2018

High-fat, high-cholesterol diet depletes ranks of artery-protecting immune cells

New research from scientists at the La Jolla Institute for Allergy and Immunology shows how a diet high in fat and cholesterol depletes the ranks of artery-protecting immune cells, turning them into promoters of inflammation, which exacerbate atherosclerotic plaque buildup that occurs in cardiovascular disease.

21 Mar 2018

New study identifies key role for particular gene in 16p11.2 deletion syndrome

In a new study of one of the most common genetic causes of autism, neuroscientists at MIT's Picower Institute for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of neurons in affected mice to properly incorporate changes driven by experience.

20 Mar 2018

Adults skipping vaccines may miss out on effective new shingles shot

Federal officials have recommended a new vaccine that is more effective than an earlier version at protecting older adults against the painful rash called shingles. But persuading many adults to get this and other recommended vaccines continues to be an uphill battle, physicians and vaccine experts say.

20 Mar 2018

Immune System News and Research

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Researchers create new compound that appears to activate cancer-fighting T cells

Researchers unravel immunopathogenesis of Johne's disease

Monash scientists discover how gonorrhea-causing superbug evades the immune system

FDA grants accelerated approval to leukemia drug for patients with MRD-positive ALL

Phase I clinical trial of HIV vaccines to begin in the U.S.

New test detects Zika antibodies with high specificity

New 'nanotweezers' could pave way for innovations in health monitoring and mobile technology

Antibiotic use linked to higher risk of severe viral disease in mice

New analysis describes how childhood obesity 'pandemic' promotes cancer

Two immunotherapies used together for the first time to fight against solid tumors

Specific immune cells may help slow progression of ALS, research shows

Researchers propose alternative treatment to target lymphoma signaling at its root

Researchers prove link between common childhood cancer and inflammation

Neem Biotech to share findings on cystic fibrosis biofilm disruption at ECFS Basic Science Conference

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Immune cells can repopulate in the retina after elimination, mice study shows

High-fat, high-cholesterol diet depletes ranks of artery-protecting immune cells

New study identifies key role for particular gene in 16p11.2 deletion syndrome

Adults skipping vaccines may miss out on effective new shingles shot

Understanding the DNA Damage Response in Innate Immunity eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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