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Largest review of Loeys-Dietz syndrome to date

At least three severe, potentially fatal genetic diseases leave patients with aortas so flimsy that they can rupture in pregnancy and labor or even lesser activities, often without warning.

31 Aug 2006

Hopkins develops online tool to aid research on certain "orphan diseases"

Many people are afflicted with rare illnesses of unknown cause, and finding a common link to such under-studied or "orphaned" diseases as Bardet-Biedl, Alstrom and Meckel-Gruber syndromes can significantly advance the search for causes and treatment.

31 Aug 2006

Most effective treatments for people with coronary artery disease

Medication, angioplasty or surgery? For some heart disease patients, there's no clear-cut choice. The key to getting the best care is to follow your individual doctor's advice, new research shows.

31 Aug 2006

New cell-based targets for treating autoimmune inflammatory diseases

Patients with systemic autoimmune diseases such as lupus and rheumatoid arthritis (RA) often suffer loss of kidney function.

31 Aug 2006

Orange juice could potentially play an important role in the management of kidney stone disease

A daily glass of orange juice can help prevent the recurrence of kidney stones better than other citrus fruit juices such as lemonade, researchers at UT Southwestern Medical Center have discovered.

31 Aug 2006

Researchers analyze increases in medical expenses versus improvements in health

Despite dramatic increases in health expenses since 1960, the return on medical spending is high, according to a new study by researchers at Harvard University and the University of Michigan.

30 Aug 2006

Variation in 3 genes influences risk of age-related macular degeneration

Researchers in Boston have discovered a new common, noncoding variant in the Complement Factor H (CFH) gene that is associated with age-related macular degeneration (AMD), the leading cause of irreversible visual impairment and blindness among persons aged 60 and older.

30 Aug 2006

March of Dimes urges FDA to approve Gestiva

The March of Dimes has urged Food and Drug Administration officials to promptly approve a commercial progesterone therapy that appears to prevent some premature births.

30 Aug 2006

Anger and hostility compromise lung function and hasten the natural decline in lung power

Longstanding anger and hostility compromise lung function and hasten the natural decline in lung power that is a normal part of aging, reveals research published ahead of print in Thorax.

30 Aug 2006

Mitochondrial DNA sequencing tool updated

High-tech laboratory tools, like computers, are often updated publicly as their analytical capabilities expand. In the September issue of the Journal of Molecular Diagnostics, NIH grantees report they have developed a second generation "lab on a silicon chip" called the MitoChip v2.0 that for the first time rapidly and reliably sequences all mitochondrial DNA.

30 Aug 2006

NIH seeks input on proposed repository for genetic information

The National Institutes of Health (NIH) is seeking public input on a proposed new policy designed to facilitate the research community's access to data resulting from NIH-funded, genome-wide association studies.

30 Aug 2006

Purdue Pharma announces agreement to end OxyContin patent lawsuit with Teva Pharmaceuticals

Purdue Pharma L.P. of Stamford, Connecticut and Teva Pharmaceuticals USA, Inc. of North Wales, Pennsylvania have agreed to end their lawsuit concerning certain Purdue Pharma patents on OxyContin (oxycodone HCl controlled-release) Tablets.

30 Aug 2006

Celebrex shown to reduce incidence of potentially pre-malignant colorectal polyps

An international team of scientists reports that a single 400-milligram daily dose of celecoxib, commonly called Celebrex. and manufactured by Pfizer, significantly reduced recurrence of adenomas, or pre-malignant colon tumors - within three years of previous adenoma removal.

30 Aug 2006