Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

IgM/IgG ratio is useful in diagnosing primary biliary cirrhosis

Previous studies have shown that assessment of immunoglobulin subclasses in plasma cells by immunohistochemistry (IHC) may be useful in the histopathologic evaluation of autoimmune liver diseases. However, further studies are necessary in order to validate the diagnostic utility of IgM and IgG immunohistochemistry in this specific scenario.

10 Feb 2010

East Cooper Medical Center to install LiveData and KARL STORZ Endoscopy- America's Patient-Aware OR solutions

LiveData and KARL STORZ Endoscopy- America, Inc. today announced that East Cooper Medical Center will install the companies' Patient-Aware OR solution in the eight operating rooms in East Cooper's new hospital to be opened this quarter. KARL STORZ is a global leader in minimally invasive endoscopic technologies and operating room integration. LiveData is a leader in real-time data integration and display technology.

9 Feb 2010

Study validates Transgenomic's COLD-PCR technology for colorectal tumor-associated KRAS mutation detection

Transgenomic, Inc. announced today that it has completed a preliminary study with a leading pharmaceutical company that validates the use of its licensed COLD-PCR technology to detect colorectal tumor-associated KRAS mutations that determine efficacy of recently developed therapies. These were detected in plasma samples in which the mutation levels were too low for detection by standard DNA analysis methodologies such as Sanger sequencing.

9 Feb 2010

FDA accepts Psyadon Pharmaceuticals' ecopipam IND for treatment of LND

Psyadon Pharmaceuticals, Inc. today announced that the United States Food and Drug Administration (FDA) has accepted its Investigational New Drug Application (IND) to study ecopipam in patients with Lesch-Nyhan Disease (LND). The first center at which the drug will be evaluated is Emory University under the direction of Dr. Hyder A. Jinnah, MD, PhD. The study is designed to evaluate the safety and tolerability of different doses of ecopipam in adults (group 1), adolescents (group 2) and children (group 3) with LND.

9 Feb 2010

Journal highlights toxic nature of herbal medicines

A University of Adelaide forensic pathologist has sounded a worldwide warning of the potential lethal dangers of herbal medicines if taken in large quantities, injected, or combined with prescription drugs.

9 Feb 2010

Plant-produced antibodies can help prevent infection

The first head-to-head comparison of therapeutic monoclonal antibodies produced from plants versus the same antibodies produced from mammalian cells has shown that plant-produced antibodies can fight infection equally well.

9 Feb 2010

Investigational drug for osteoporosis inhibits serotonin synthesis in the gut

An investigational drug that inhibits serotonin synthesis in the gut, administered orally once daily, effectively cured osteoporosis in mice and rats reports an international team led by researchers from Columbia University Medical Center, in the Feb. 7 issue of Nature Medicine.

7 Feb 2010

Breakthrough research could lead to new potential treatments for malaria

Groundbreaking research done at Singapore's Nanyang Technological University's (NTU) School of Biological Sciences (SBS) could lead to the development of more potent drugs or a vaccine for malaria, which is transmitted to humans by infected mosquitoes and kills up to three million people each year.

6 Feb 2010

In jobs bill, Democrats push to include extension of COBRA benefits, Medicare 'doc fix'

The New York Times reports that Democrats are trying to address some health coverage considerations in their jobs bill even as they grasp "for ideas to keep alive their health care legislation." Negotiators on the Senate Finance Committee may be close to a jobs agreement. "Democrats were also pushing to include an extension of unemployment benefits and of health care coverage for those out of work." Also under discussion was the possibility of "attaching other initiatives, including a provision to prevent a steep cut in Medicare payment rates for doctors" (Hulse and Zeleny, 2/4).

6 Feb 2010

HDC partners with New York surgery center to develop new molecular diagnostic tests for pancreatic cancer

Health Discovery Corporation announced today that the Company has entered into an exclusive agreement with the Pancreas, Biliary and Liver Surgery Center of New York at Saint Vincent Catholic Medical Centers in New York City to develop new molecular diagnostic tests for the early detection of pancreatic cancer. The Pancreas, Biliary and Liver Surgery Center is under the leadership of Drs. Michael Wayne, Franklin Kassim and Avram Cooperman.

6 Feb 2010

Study suggests molecules and pathways in mood regulation and circadian rhythms are intertwined

Scientists at Emory University School of Medicine have discovered unexpected properties for a precursor to melatonin, the hormone that regulates sleep cycles.

5 Feb 2010

Elephantiasis and river blindness: MSU researcher receives $2M for reformulating flubendazole

In an effort to eliminate the tropical diseases elephantiasis and river blindness, a Michigan State University researcher has been awarded $2 million to reformulate an existing drug that could stop the debilitating diseases in their tracks.

5 Feb 2010

ARUP Laboratories adds three downstream cost calculators to its Suite of Utilization Management Services

ARUP Laboratories announced the release of three groundbreaking tools, downstream cost calculators, to its Suite of Utilization Management Services.

5 Feb 2010

Health Discovery receives final patent infringement payment from Vermillion

Health Discovery Corporation announced today that the Company has received the final payment that was due under the agreement that settled the Company’s patent infringement lawsuit against Vermillion, formerly known as Ciphergen Biosystems, Inc.

4 Feb 2010

Court weighs patents for human genes

The American Civil Liberties Union has sued a genetics company that holds patents on breast- and ovarian-cancer-causing genes, saying their claims on the two genes hinders further research by other companies and scientists, the Associated Press/CBS News reports.

4 Feb 2010

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Repros Therapeutics Inc. today announced that the Company has received verbal confirmation from the Division of Metabolic and Endocrine Drug Products of the Food and Drug Agency that the Company may initiate its Investigational New Drug Application for the study of oral Androxal® in the treatment of hypogonadal men with Type II Diabetes (T2D) with a Phase IIa trial.

3 Feb 2010

Study could provide potential therapeutic strategies for treating prostate cancer

Prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally, according to new data from researchers at UT Southwestern Medical Center.

3 Feb 2010

Pandemic H1N1 influenza of swine origin has distinct means of transmission from seasonal flu

Current research suggests that pandemic H1N1 influenza of swine origin has distinct means of transmission from the seasonal flu, yet does not result in the pathogenic severity of avian flu viruses.

2 Feb 2010

Unusual molecule in brain and retina can trigger vision loss

Scientists have identified a double agent in the eye that, once triggered, can morph from neuron protector to neuron killer. The discovery has significant health implications since the neurons killed through this process results in vision loss and blindness.

2 Feb 2010

Study evaluates hepatocyte transplantation as an alternative to liver transplantation

A research team from the National Taiwan University Hospital has evaluated the efficiency of transplanted hepatocyte (liver) cells in animal models severely damaged by two kinds of chemical toxicity to see whether and how transplanted hepatocytes were able to efficiently repopulate the toxin-induced, severely damaged livers.

2 Feb 2010

Pathology News and Research

Further Reading

IgM/IgG ratio is useful in diagnosing primary biliary cirrhosis

East Cooper Medical Center to install LiveData and KARL STORZ Endoscopy- America's Patient-Aware OR solutions

Study validates Transgenomic's COLD-PCR technology for colorectal tumor-associated KRAS mutation detection

FDA accepts Psyadon Pharmaceuticals' ecopipam IND for treatment of LND

Journal highlights toxic nature of herbal medicines

Plant-produced antibodies can help prevent infection

Investigational drug for osteoporosis inhibits serotonin synthesis in the gut

Breakthrough research could lead to new potential treatments for malaria

In jobs bill, Democrats push to include extension of COBRA benefits, Medicare 'doc fix'

HDC partners with New York surgery center to develop new molecular diagnostic tests for pancreatic cancer

Study suggests molecules and pathways in mood regulation and circadian rhythms are intertwined

Elephantiasis and river blindness: MSU researcher receives $2M for reformulating flubendazole

ARUP Laboratories adds three downstream cost calculators to its Suite of Utilization Management Services

Health Discovery receives final patent infringement payment from Vermillion

Court weighs patents for human genes

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Study could provide potential therapeutic strategies for treating prostate cancer

Pandemic H1N1 influenza of swine origin has distinct means of transmission from seasonal flu

Unusual molecule in brain and retina can trigger vision loss

Study evaluates hepatocyte transplantation as an alternative to liver transplantation

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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