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Exploring human milk oligosaccharides as a method of COVID-19 prevention

New research was conducted to ascertain whether antiviral and immunomodulatory activities of human milk oligosaccharides can be efficacious in the prevention and treatment against COVID-19.

3 Feb 2022

Study underscores the urgent need to accelerate testing to identify undiagnosed children with HIV

Over the past two decades, important progress has been made in implementing services to prevent mother-to-child (vertical) transmission of HIV and to access and uptake of HIV testing for infants and children in countries with a high HIV burden.

2 Feb 2022

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae- chronic complications resulting from COVID-19 infection, according to a review published this week in Clinical Microbiology Reviews, a journal of the American Society for Microbiology.

2 Feb 2022

Study finds higher levels of oxytocin in men with hypersexual disorder

Men with hypersexual disorder may have higher levels of oxytocin in their blood than men without the disorder, according to a small study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

2 Feb 2022

ESHRE publishes new guideline on the diagnosis, treatment of endometriosis

A new guideline on the diagnosis, treatment and management of endometriosis has been published today (Wednesday) by the European Society of Human Reproduction and Embryology ESHRE).

2 Feb 2022

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

Researchers from China summarized the representative structures of SARS-CoV-2 proteins and discussed the development of novel therapeutic agents for targeting these proteins to treat and prevent COVID-19.

2 Feb 2022

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

Researchers at University Hospitals Seidman Cancer Center and Case Western Reserve University have developed a novel approach to chimeric antigen receptor (CAR) T-cell therapy for B-cell cancers that triples the targeted antigens on cancer cells – a "back up" approach that promises to greatly reduce the potential for antigen escape currently found in CAR T therapies that solely target CD19.

2 Feb 2022

America's system of care fails to meet the needs of traumatic brain injury survivors, say experts

Every year, nearly 5 million Americans are evaluated for traumatic brain injury in emergency departments across the country.

2 Feb 2022

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

New research posted to the medRxiv* preprint server finds patients with immune-mediated inflammatory diseases undergoing anti-TNF therapy had the greatest reduction of antibody levels three months after vaccination. In addition, they had weaker neutralization responses towards severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern.

1 Feb 2022

Experimental immunotherapy could help treat some people with metastatic breast cancer

An experimental form of immunotherapy that uses an individual's own tumor-fighting immune cells could potentially be used to treat people with metastatic breast cancer, according to results from an ongoing clinical trial led by researchers at the National Cancer Institute's Center for Cancer Research, part of the National Institutes of Health.

1 Feb 2022

New RNA therapies for the treatment of heart failure and organ fibrosis

RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based compounds is far from being fully tapped, as RNA allows for entirely new therapeutic approaches.

1 Feb 2022

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Exogenous trypsin treatment boosts SARS-CoV-2 infection in Vero E6 cells and promotes viral multiplication in cultured cells.

1 Feb 2022

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

A randomized controlled trial assesses the efficacy and safety of high-dose convalescent plasma in the treatment of severe COVID-19.

1 Feb 2022

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

In a new study, a team of researchers assessed the neutralizing activity of XAV-19, a glyco-humanized polyclonal antibody derived from hyperimmunized animal hosts, against the SARS-CoV-2 Omicron variant.

1 Feb 2022

Colleges struggle to recruit therapists for students in crisis

Early in his first quarter at the University of California-Davis, Ryan Manriquez realized he needed help. A combination of pressures — avoiding covid-19, enduring a breakup, dealing with a disability, trying to keep up with a tough slate of classes — hit him hard.

1 Feb 2022

Researchers develop new technique to open the blood-brain barrier in lab animals

University of Maryland School of Medicine researchers developed a technique in laboratory animals to consistently and reproducibly open the blood-brain barrier.

31 Jan 2022

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

A new study posted to the medRxiv* preprint server has evaluated the effect of mRNA-based COVID-19 vaccination and boosting strategy on serum antibody responses in PAD patients against the original SARS-CoV-2 strain and circulating variants.

31 Jan 2022

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Fusion oncogenes, such as RET- and NTRK-gene fusions, are associated with more invasive pediatric thyroid cancers, correlating with the highest risk of metastases and a lower likelihood of achieving remission one year after initial therapy, according to a new study by researchers at Children's Hospital of Philadelphia (CHOP).

31 Jan 2022

Dexamethasone administration at a late time point could enhance transgene expression

Dexamethasone, a glucocorticoid with anti-inflammatory and immunosuppressive effects, can transiently increase the expression of therapeutic genes delivered using adeno-associated virus (AAV) vectors.

31 Jan 2022

Open-label placebo shows promise as therapy for disorders of gut-brain interaction in children

Pain-predominant disorders of gut-brain interaction (DGBIs) in children - such as functional abdominal pain (FAP) and irritable bowel syndrome (IBS) - can lead to disabling symptoms, poor quality of life and high use of health care resources.

31 Jan 2022

Therapy News and Research

Exploring human milk oligosaccharides as a method of COVID-19 prevention

Study underscores the urgent need to accelerate testing to identify undiagnosed children with HIV

Combined treatment strategy essential to minimize lung sequelae in COVID-19 patients

Study finds higher levels of oxytocin in men with hypersexual disorder

ESHRE publishes new guideline on the diagnosis, treatment of endometriosis

Representative structures of SARS-CoV-2 and development of therapeutic agents for targeting these proteins

New approach to CAR T-cell therapy for B-cell cancers triples the targeted antigens on cancer cells

America's system of care fails to meet the needs of traumatic brain injury survivors, say experts

Research supports the need for a 3rd mRNA COVID vaccine in patients taking immunosuppressants

Experimental immunotherapy could help treat some people with metastatic breast cancer

New RNA therapies for the treatment of heart failure and organ fibrosis

SARS-CoV-2 entry at the cell surface facilitated by trypsin

Study finds that high-dose convalescent plasma does not improve outcomes for severe COVID-19

Assessing the neutralizing ability of polyclonal antibody XAV-19 against SARS-CoV-2 Omicron variant

Colleges struggle to recruit therapists for students in crisis

Researchers develop new technique to open the blood-brain barrier in lab animals

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

Fusion oncogenes associated with more invasive pediatric thyroid cancers, study says

Dexamethasone administration at a late time point could enhance transgene expression

Open-label placebo shows promise as therapy for disorders of gut-brain interaction in children

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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