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Burkitt lymphoma gene expression signature identified

An international research study involving the University of Nebraska Medical Center, the National Cancer Institute and 10 other institutions has successfully identified the gene expression signature for Burkitt lymphoma.

14 Jun 2006

Dasatinib offers new options for leukemia patients

Dasatinib, an experimental drug under development by Bristol-Myers Squibb, reverses the signs and symptoms of patients whose chronic myeloid leukemia has failed to respond to Gleevec, which is considered the standard of treatment for the disorder.

14 Jun 2006

Elevation of fat-derived molecule foretells early insulin resistance

A study in the June 15 issue of The New England Journal of Medicine (NEJM) reveals that elevated levels of a molecule called RBP4 (retinol binding protein 4) can foretell early stages in the development of insulin resistance.

14 Jun 2006

Scientists watch the behavior of a single gene in real time

Scientists at the Albert Einstein College of Medicine of Yeshiva University have observed for the first time that gene expression can occur in the form of discrete "pulses" of gene activity.

14 Jun 2006

Restricting carbohydrates may prevent Alzheimer's disease

A recent study directed by Mount Sinai School of Medicine suggests that experimental dietary regimens might calm or even reverse symptoms of Alzheimer's Disease (AD).

14 Jun 2006

Prozac saves thousands of lives

A new study should help alleviate any concern over a link between the use of certain antidepressants and suicide.

13 Jun 2006

Hospitals, dirty hands and the risk of disease

Thousands of patients in hospitals each year are at risk of potentially fatal infections because health care workers do not wash their hands on enough occasions.

13 Jun 2006

New test identifies patients who benefit from targeted cancer drugs

New lab test accurately identified patients who would benefit from treatment with the molecularly-targeted anti-cancer therapies gefitinib (Iressa, AstraZeneca) and erlotinib (Tarceva, Genentech).

13 Jun 2006

Parkinson's patients stomach new drug better than conventional meds

Several studies conducted at Baylor College of Medicine (BCM) in Houston show that a new kind of orally disintegrating tablets provides improved symptom relief for patients with Parkinson's disease.

13 Jun 2006

The n-of-1 trial: An opportunity for complementary and alternative medicine evaluation

It is an extremely interesting rationale for the use of n-of-1 randomized trials, particularly for complementary and alternative medicine evaluation in the treatment of chronic, difficult to treat disorders.

13 Jun 2006

Coffee may help prevent cirrhosis of the liver

Researchers in the U.S. suggest that drinking coffee may help protect against alcohol-related cirrhosis of the liver.

12 Jun 2006

Mechanism for neurodenegerative diseases linked to transport proteins

Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.

9 Jun 2006

Research explains how pathogenic bacteria evolved over millions of years

Bacteria like Salmonella have a complicated immune system that helps them recognize and isolate foreign DNA trying to invade their cell membrane, according to a University of Washington-led study in the June 8 issue of Science Express.

9 Jun 2006

Japanese researchers using PET imaging detect the beginnings of atherosclerosis

Using positron emission tomography (PET), the medical isotope 15O-water and cold pressor tests, Japanese researchers were able to detect the beginnings of atherosclerosis - before the disease became clinically evident.

9 Jun 2006

How cow warts, clergy sex surveys moved along cervical cancer vaccine

The creation of a successful vaccine against cervical cancer, approved today by the U.S. Food and Drug Administration, is the culmination of research that occurred thanks not only to scientists and physicians, but also to generous farmers and veterinarians, priests and nuns willing to tell all - and some very patient cows.

9 Jun 2006

FDA approves Gardasil as a treatment for cervical cancer

Merck & Co. has announced that the U.S. Food and Drug Administration (FDA) approved Gardasil as a treatment for cervical cancer, vulvar and vaginal pre-cancers caused by HPV types 16 and 18 and to prevent low-grade and pre-cancerous lesions and genital warts caused by HPV types 6, 11, 16 and 18.

9 Jun 2006

The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection

Researchers at Karolinska Institutet in Sweden have succeeded in explaining how the body protects itself against urinary tract infections; with the help of an endogenous antibiotic.

9 Jun 2006

Radionuclide therapy with chemotherapy effective in treating prostate cancer

A new treatment for prostate cancer may provide a distinct advantage over other conventional protocols and induce actual regression of the disease - not just relief from bone pain or a limited control of the disease.

9 Jun 2006

Protein called Elk-1appears to play role in neurodegeneration and schizophrenia

Pprotein called Elk-1 interacts with mitochondria, the energy storehouse of a cell, suggesting that this protein - typically active in the nucleus - could play a role in cell death and mitochondria-related diseases such as neurodegeneration and schizophrenia.

9 Jun 2006

COX enzymes work together in ways that suggest new biological roles

COX enzymes - well-known for their contrasting role in cardiovascular biology - interact physically to form a previously unrecognized biochemical partnership and function in the development of blood vessels in a mouse model.

9 Jun 2006