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Researchers develop silica nanostructure for selective synthesis of enantiomers in cells

As COVID-19 vaccinations are well underway, people await a return to normal life. However, fears also grow due to unforeseen side effects like rare thrombosis. In the body, life is maintained by the movement of substances or energy.

13 Aug 2021

Camelid nanobody anti-SARS-CoV-2 drug candidates

In a research paper recently published in the journal eLife, researchers from several US institutions have developed a nanobody-based candidate drug that effectively prevents and suppresses severe SARS-CoV-2 infection in animals.

12 Aug 2021

Popular painkillers can be used as personal dosimeters in a radiation emergency

When proper precautions are taken, radioactive substances are extremely safe to use. But what if they leak into the environment in an uncontrolled manner? Then it becomes crucial to find out the dose of radiation people may have absorbed.

12 Aug 2021

Study finds cognitive safety of ketamine and esketamine for patients with treatment-resistant depression

Used for the treatment of depression that does not respond to standard antidepressant medications, the anesthesia drug ketamine – and the related drug esketamine, recently approved for depression treatment – has no important adverse effects on memory, attention, or other cognitive processes, concludes a systematic review of medical research in the September/October issue of Harvard Review of Psychiatry.

12 Aug 2021

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

A team of Massachusetts General Hospital researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies.

12 Aug 2021

Temple researchers receive $1.25M NIH grant to advance understanding of neurodegenerative diseases

Like wear and tear that causes electrical systems to short circuit, neurons in the human nervous system are susceptible to degenerative processes that disrupt the flow of information.

12 Aug 2021

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Antisense oligonucleotide (ASO) therapy has the potential to ameliorate many neurodegenerative diseases at the genetic level to suppress the production of harmful proteins or non-coding RNAs.

12 Aug 2021

Study finds worsening disparities among states in use of HIV-prevention drugs

States with low initial use of HIV-prevention drugs are continuing to fall behind in usage among people at risk for the disease, a new study finds.

12 Aug 2021

Researchers determine the structure of receptor involved in type 2 diabetes and other pathologies

Researchers from the University of Southern California, Merck & Co., Skoltech, MIPT, UCLA, and the Université de Sherbrooke have determined the structure of the human leukotriene B4 receptor 1, involved in inflammatory, infectious, allergic, and tumorigenic diseases.

12 Aug 2021

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Results from a Michigan Medicine study reveal that targeting a protein found in the skin may reduce the severity of psoriasis.

12 Aug 2021

Study finds new pair of gene variants that causes sudden onset of hypertension in pregnant women

An international study, led by researchers from Queen Mary University of London and St Bartholomew's Hospital, has found a unique pair of gene variants that causes sudden onset high blood pressure in pregnant women.

12 Aug 2021

FDA approves a new indication for chronic sleep disorder treatment

The U.S. Food and Drug Administration today approved a new indication for Xywav for idiopathic hypersomnia (IH) in adults.

12 Aug 2021

Study unlocks genetic treasure chest for chronic kidney disease

Despite impacting an estimated 850 million people and being responsible for 1 in 60 deaths worldwide, few treatments are available for chronic kidney disease.

12 Aug 2021

KHN’s ‘What the Health?’: The Senate acts

The Senate has set the stage for a busy fall that will include debate on a broad array of health issues, such as prescription drug prices, Medicare expansion and further expansion of the Affordable Care Act.

12 Aug 2021

National academies’ report took pharma-friendly stance after millions in gifts from drugmakers

To several U.S. senators, it looked wasteful, even outrageous. Every year, taxpayers pay for at least $750 million worth of expensive pharmaceuticals that are simply thrown away. Companies ship many of the drugs in "Costco"-size vials, one lawmaker said, that once opened usually cannot be resealed or saved for other patients. Yet pharma gets paid for every drop.

12 Aug 2021

New research offers hope to increase efficacy of immunotherapy for lung cancer

Lung cancer is the leading cause of cancer-related death. Current treatments employ immunotherapy, often in combination with chemotherapy, but benefits to patients remain slight.

11 Aug 2021

ACR applauds CMS' decision to withdraw the "Most Favored Nation" payment model for Part B drugs

The American College of Rheumatology today applauded the Centers for Medicare and Medicaid Services' decision to withdraw a proposed rule to implement the "Most Favored Nation" payment model for Part B drugs.

11 Aug 2021

Immunogenicity of mRNA vaccine against emerging strains of SARS-CoV-2 in immunocompromised patients

A study measured neutralization of SARS-CoV-2 and vaccine responses in immunocompromised patients with systemic inflammatory diseases.

11 Aug 2021

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

A recent study discusses the clinical characteristics and outcomes of patients with SARDs who were previously vaccinated against SARS-CoV-2.

11 Aug 2021

CBD may reduce the adverse effects of anti-seizure drugs in people with epilepsy

Artisanal (non-pharmaceutical) cannabidiol (CBD) products have become popular in recent years for their apparent therapeutic effects. CBD — a naturally occurring compound of the cannabis plant legally derived from hemp — is used widely as a naturopathic remedy for a number of health conditions, including epilepsy and seizure disorders.

11 Aug 2021

Drugs News and Research

Researchers develop silica nanostructure for selective synthesis of enantiomers in cells

Camelid nanobody anti-SARS-CoV-2 drug candidates

Popular painkillers can be used as personal dosimeters in a radiation emergency

Study finds cognitive safety of ketamine and esketamine for patients with treatment-resistant depression

Researchers discover how PARP inhibitors selectively kill BRCA-mutant cancer cells

Temple researchers receive $1.25M NIH grant to advance understanding of neurodegenerative diseases

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Study finds worsening disparities among states in use of HIV-prevention drugs

Researchers determine the structure of receptor involved in type 2 diabetes and other pathologies

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Study finds new pair of gene variants that causes sudden onset of hypertension in pregnant women

FDA approves a new indication for chronic sleep disorder treatment

Study unlocks genetic treasure chest for chronic kidney disease

KHN’s ‘What the Health?’: The Senate acts

National academies’ report took pharma-friendly stance after millions in gifts from drugmakers

New research offers hope to increase efficacy of immunotherapy for lung cancer

ACR applauds CMS' decision to withdraw the "Most Favored Nation" payment model for Part B drugs

Immunogenicity of mRNA vaccine against emerging strains of SARS-CoV-2 in immunocompromised patients

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

CBD may reduce the adverse effects of anti-seizure drugs in people with epilepsy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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