Inflammation News and Research

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New experimental growth factor drug appears to prevent worsening of osteoarthritis

More than 10 percent of Americans over age 60 experience knee pain related to osteoarthritis, the most common disease of the knee joint. Osteoarthritis of the knee causes pain, activity limitation, physical disability, reduced health-related quality of life and excess mortality compared with the general population.

8 Oct 2019

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.

8 Oct 2019

UVA researchers uncover key contributor to multiple sclerosis

Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the University of Virginia School of Medicine shows.

8 Oct 2019

Blocking a protein in immune cells may help reduce risk of heart attack and stroke

Blocking the mineralocorticoid receptor (MR)- a protein that helps maintain normal levels of salt and water in the body- in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health.

7 Oct 2019

Study identifies a common denominator that triggers asthma in favorable environments

In recent decades, asthma has become a major public health problem. The exponential increase in asthma cases in industrialized countries over the past 50 years is due to major changes in our environment.

7 Oct 2019

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

Cincinnati Children's Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic gastrointestinal disorders.

7 Oct 2019

New genome-wide association study shines light on genetic risk factors for gout

Researchers, using a method called genome-wide association study, have illuminated the genetic underpinnings of high serum urate, the blood condition that brings on gout.

7 Oct 2019

Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

Dry skin, pain, and itching... Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients.

7 Oct 2019

Study shows association between mushroom consumption and lower risk of prostate cancer

Results from the first long-term cohort study of more than 36,000 Japanese men over decades suggest an association between eating mushrooms and a lower risk of prostate cancer.

7 Oct 2019

Researchers determine how the colon prioritizes gas detox over energy use

Onions, cabbage, garlic. While nutritious, eating these foods can lead to an embarrassing side effect: smelly flatulence. More than just smelly, hydrogen sulfide, the chemical compound responsible for the rotten-egg aroma, is deadly if inhaled at doses of more than 700 parts per million.

7 Oct 2019

Study identifies genetic marker which could personalize treatment for Crohn's disease

The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment.

7 Oct 2019

Exercise can help protect cancer patients' heart from negative effects of therapies

Patients with cancer should receive a tailored exercise prescription to protect their heart, reports a paper published today in the European Journal of Preventive Cardiology, a journal of the European Society of Cardiology.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

New defensive mechanism against bacterial wound infections discovered

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité - Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria.

4 Oct 2019

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Multiple sclerosis, an autoimmune disorder, is known to be driven by "helper" T cells, white blood cells that mount an inflammatory attack on the brain and spinal cord. A new study from Boston Children's Hospital pinpoints the specific subgroup of helper T cells that cause MS, as well as a protein on their surface, called CXCR6, that marks them.

4 Oct 2019

Research supports role of efficacy-first natural regimens to restore and improve skin health

Burt's Bees, a pioneer in natural skin care, today announced research supporting the role of efficacy-first natural regimens to defend, restore and improve skin health.

4 Oct 2019

Researchers are developing new therapy to counter the effects of traumatic brain injury

A blow to the head or powerful shock wave on the battlefield can cause immediate, significant damage to a person's skull and the tissue beneath it.

4 Oct 2019

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome.

4 Oct 2019

Chronic inflammation of the placenta linked to African-American preterm births

African-American infants are twice as likely to die in the first year of life than white infants, for reasons that are complex and not well understood. Results from a recent study suggest that specific abnormalities in the placenta from African-American preterm births may hold clues to the physical mechanisms behind racial disparities in preemie health outcomes.

3 Oct 2019

Researchers observe the working of protein associated with numerous health problems

For the first time, researchers have observed at the molecular level how a protein associated with numerous health problems works.

3 Oct 2019

Inflammation News and Research

New experimental growth factor drug appears to prevent worsening of osteoarthritis

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

UVA researchers uncover key contributor to multiple sclerosis

Blocking a protein in immune cells may help reduce risk of heart attack and stroke

Study identifies a common denominator that triggers asthma in favorable environments

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

New genome-wide association study shines light on genetic risk factors for gout

Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

Study shows association between mushroom consumption and lower risk of prostate cancer

Researchers determine how the colon prioritizes gas detox over energy use

Study identifies genetic marker which could personalize treatment for Crohn's disease

Exercise can help protect cancer patients' heart from negative effects of therapies

Common genetic variant explains why immunotherapy often fails in Crohn's disease

New defensive mechanism against bacterial wound infections discovered

Antibody that targets CXCR6 prevents and reverses multiple sclerosis in mouse model

Research supports role of efficacy-first natural regimens to restore and improve skin health

Researchers are developing new therapy to counter the effects of traumatic brain injury

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

Chronic inflammation of the placenta linked to African-American preterm births

Researchers observe the working of protein associated with numerous health problems

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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