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Saint Louis University hunt for a Hepatitis C vaccine

Human clinical trials involving investigational vaccines to prevent Hepatitis C are rare. In the fall of 2003 there was a first-ever study at Saint Louis University Center for Vaccine Development, and an earlier small study at Johns Hopkins School of Medicine.

3 May 2006

Death risks high in younger people with diabetes

People with Type 2 diabetes aged between 35 and 54 are over three times more likely to die than those without the condition according to research published in the journal Diabetic Medicine.

3 May 2006

DARPA grant supports research toward realizing tissue regeneration

While U.S. soldiers fighting in Iraq and Afghanistan are surviving injuries that in previous conflicts likely would have been fatal, the number of wounded with major tissue loss has never before been so high.

3 May 2006

Differential effects of HOXB4 on nonhuman primate short and long-term repopulating cells

Transplantation of hematopoietic stem cells (HSCs, the cells that can give rise to all blood and most immune cell types) can save patients whose own hematopoietic system is defective or has been destroyed (often through radiation or chemotherapy of cancer).

3 May 2006

More effective influenza vaccine

An intranasal influenza vaccine proved to be more effective than the injectable influenza vaccine in children older than 6 months and younger than 5 years of age, according to study data presented at the annual meeting of the Pediatric Academic Societies in San Francisco.

3 May 2006

Obtaining and documenting informed patient consent prior to surgery

Obtaining and documenting informed patient consent prior to surgery is of vital importance, but both the process and documentation of consent can be inadequate.

3 May 2006

Endocannabinoid system shows promise in combating obesity

As the obesity epidemic grows in the United States, the medical community is faced with the significant challenge of properly treating patients before complications such as heart disease arise.

3 May 2006

African American men have fewer, less severe coronary obstructions than white males

While African American men are more likely to die from cardiovascular disease, they paradoxically have fewer cases of coronary obstruction than clinically similar white men, according to a new national study led by a Medical College of Wisconsin researcher.

3 May 2006

Varenicline could increase number who quit smoking

Smokers who try to quit using existing medications, such as nicotine patches or Zyban, are about twice as likely to succeed as those who don't use medication or are prescribed placebos during clinical trials.

3 May 2006

Virtual reality simulation technology improves carotid angiography skills

Cardiologists can learn to perform risky catheter procedures such as carotid angiography on a virtual patient simulator, rather than on real patients, according to a new study in the May 2, 2006, issue of the Journal of the American College of Cardiology.

3 May 2006

Olanzapine appears to lower or delay full-blown psychosis

For young people who clearly seem to be developing early signs of schizophrenia, treatment with the antipsychotic drug olanzapine appears to lower or delay the rate of conversion to full-blown psychosis, according to an article by a Yale School of Medicine researcher in the May issue of The American Journal of Psychiatry.

3 May 2006

Inflammation markers identify fatigue in breast cancer survivors

Researchers at the University of California, Los Angeles have defined conditions associated with disabling fatigue that persists for years in almost a third of breast cancer survivors, according to a study in the May 1 issue of Clinical Cancer Research.

3 May 2006

Current US drug safety system is moving toward a delay in drug approval

In the May 3 issue of the Journal of the American Medical Association, Brian L. Strom, MD, MPH, Professor of Public Health and Preventive Medicine and Chair of the Department of Biostatistics and Epidemiology at the University of Pennsylvania School of Medicine, analyzes the limitations of the current system of drug-safety monitoring and proposes a solution that addresses overly aggressive early marketing practices

3 May 2006

Parents rarely use baby gates

A recent study by researchers in emergency medicine at Cincinnati Children's Hospital Medical Center found parents use baby gates and bath thermometers less than 25 percent of the time and pediatricians are partially to blame.

3 May 2006

New drug lixivaptan reduces excess fluid build-up in patients with congestive heart failure

Researchers believe they may have identified a new agent to reduce the excess fluid build-up in patients with congestive heart failure, one that avoids the relative sodium-depleting effects of diuretics, now the most commonly used drugs for this purpose.

3 May 2006

Traffic, susceptibility and childhood asthma

Young children who live near a major road are significantly more likely to have asthma than children who live only blocks away, according to a study that appears in Environmental Health Perspectives.

3 May 2006

Surgeons exhibit the lowest level of teamwork and nurses the highest in the operating room

A study based on a survey measuring attitudes toward the work environment in the operating room (OR) reveals that surgeons exhibit the lowest level of teamwork and nurses the highest.

3 May 2006

Identification of CPT1c gene that the brain needs to manage body weight

Working with genetically engineered mice, Johns Hopkins scientists have interfered with the brain's ability to control an animal's response to a high-fat diet.

3 May 2006

Obesity in the U.S. greatly underestimated

Researchers at the Harvard School of Public Health (HSPH) analyzed data from health surveys, which are used to estimate obesity levels in states. Because people tend to provide incorrect information about their weight and height, especially in telephone surveys, the researchers concluded that estimates of obesity in individual states have been too low, by more than 50%.

3 May 2006

Researchers recommend national uniform newborn screening tests

In a new study, conducted for the federal government and published in a supplement to the May issue of the journal Pediatrics, Stephen M. Downs, M.D. and Aaron E. Carroll, M.D., of the Indiana University School of Medicine, recommend a national uniform panel of newborn screening tests which they found to be cost saving as well as life saving.

3 May 2006